Circadian rhythm of cytochrome P4502E1 and its effect on disposition kinetics of chlorzoxazone in rats

European Journal of Pharmacology

Volumn 574, Issue 1, 2007, Pages 71-76

  Khemawoot, Phisit ^a   Nishino, Kousuke ^b   Ishizaki, Junko ^b   Yokogawa, Koichi ^a,b   Miyamoto, Ken ichi ^a,b  

^a Graduate School of Human Health Science   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Chlorzoxazone; Circadian rhythm; Cytochrome P4502E1

Indexed keywords

6 HYDROXYCHLORZOXAZONE; CHLORZOXAZONE; CYTOCHROME P450 2E1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DRUG HALF LIFE; ENZYME ACTIVITY; ENZYME KINETICS; HYDROXYLATION; KIDNEY MICROSOME; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WISTAR RAT;

ANIMALS; AREA UNDER CURVE; CHLORZOXAZONE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCADIAN RHYTHM; CYTOCHROME P-450 CYP2E1; HALF-LIFE; HYDROXYLATION; KIDNEY; LIVER; MALE; MICROSOMES; MUSCLE RELAXANTS, CENTRAL; RATS; RATS, WISTAR; RNA, MESSENGER; TISSUE DISTRIBUTION;

EID: 34848844043     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.06.032     Document Type: Article

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