Rapid and sensitive high-performance liquid chromatographic assay for 6-hydroxychlorzoxazone and chlorzoxazone in liver microsomes

Journal of Chromatography B: Biomedical Applications

Volumn 693, Issue 2, 1997, Pages 479-483

  Chittur, Sridar V ^a   Tracy, Timothy S ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

6 Hydroxychlorzoxazone; Chlorzoxazone

Indexed keywords

CHLORZOXAZONE; DRUG METABOLITE; PHENACETIN;

ACCURACY; ANIMAL TISSUE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RAT; TECHNIQUE; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; CHLORZOXAZONE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MALE; MICROSOMES, LIVER; MUSCLE RELAXANTS, CENTRAL; RATS; RATS, SPRAGUE-DAWLEY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0030927305     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(97)00024-8     Document Type: Article

References (9)

1. A.H. Conney and J.J. Burns, J. Pharmacol. Exp. Ther., 128 (1960) 340.
2. R. Peter, R. Bocker, P.H. Beaune, M. Iwasaki, F.P. Guengerich and C.S. Yang, Chem. Res. Toxicol., 3 (1990) 566.
3. V. Carriere, T. Goasduff, D. Ratanasavanh, F. Morel, J.-C. Gautier, A. Guillouzo, P. Beaune and F. Berthou, Chem. Res. Toxicol., 6 (1993) 852.
4. R.B. Kim, D. O'Shea and G.R. Wilkinson, Pharmacogenetics, 4 (1994) 162.
5. I.L. Honigberg, J.T. Stewart and J.W. Coldren, J. Pharm. Sci., 68 (1979) 253.
6. R.K. Desiraju, N.L. Renzi, R.K. Nayak and K.T. Ng, J. Pharm. Sci., 72 (1983) 991.
7. J.T. Stewart and H.K. Carter, J. Chromatogr., 380 (1986) 177.
8. C.D. Gaitonde and P.V. Pathak, J. Chromatogr., 528 (1990) 407.
9. D.D. Stiff, R.F. Frye and R.A. Branch, J. Chromatogr., 613 (1993) 127.