The natural product berberine is a human prolyl oligopeptidase inhibitor

ChemMedChem

Volumn 2, Issue 3, 2007, Pages 354-359

  Tarrago, Teresa ^a   Kichik, Nessim ^a   Segu, Josep ^b   Giralt, Ernest ^a,b  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Berberine; Fluorine NMR spectroscopy; Prolyl oligopeptidase; Schizophrenia; Traditional Chinese medicine

Indexed keywords

BERBERINE; BIOLOGICAL PRODUCT; PROLYL ENDOPEPTIDASE; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR;

ARTICLE; BINDING SITE; CHEMISTRY; CHINESE MEDICINE; DRUG EFFECT; HUMAN; METABOLISM; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; SCHIZOPHRENIA;

BERBERINE; BINDING SITES; BIOLOGICAL PRODUCTS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MEDICINE, CHINESE TRADITIONAL; NERVOUS SYSTEM DISEASES; SCHIZOPHRENIA; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS;

EID: 34748916412     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200600303     Document Type: Article

References (39)

1. L. M. Brzustowicz, K. A. Hodgkinson, E. W. Chow, W. G. Honer, A. S. Bassett, Science 2000, 288, 678-682.
2. J. Bobes, F. Canas, F. Rejas, J. Mackell, Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2004, 28, 1287-1297.
3. D. A. Lewis, J. A. Lieberman, Neuron. 2000, 28, 325-334.
4. T. S. Stroup, W. M. Alves, R. M. Hamer, J. A. Lieberman, Nat. Rev. Drug Discov. 2006, 5, 133-146.
5. S. A. Castner, P. S. Goldman-Rakic, G. V. Williams, Psychopharm. 2004, 174, 111-125.
6. S. B. Floresco, M. A. Geyer, L. H. Gold, A. A. Grace, Schizophrenia 2005, 31, 888-894.
7. L. Cheng, M. Lumb, L. Polgar, A. W. Mudge, Mol Cell Neurosci. 2005, 29, 155-161.
8. Y. Komatsu, J. Neurosci. 1996, 16, 6342-6352.
9. I. Schulz, B. Gerhartz, A. Neubauer, A. Holloschi, U. Heiser, M. Hafner, H. U. Demuth, Eur. J. Biochem. 2002, 269, 5813-5820.
10. R. S. Williams, M. Eames, W. J. Ryves, J. Viggars, A. J. Harwood, Embo J. 1999, 18, 2734-2745.
11. R. S. Williams, L. Cheng, A. W. Mudge, A. J. Harwood, Nature 2002, 417, 292-295.
12. M. Maes, F. Goossens, S. Scharpe, J. Calabrese, R. Desnyder, H. Y. Meltzer, Psychiatry 1995, 58, 217-225.
13. K. Toide, Y. Iwamoto, T. Fujiwara, H. Abe, J. Pharmacol. Exp. Ther. 1995, 274, 1370-1378.
14. M. Shinoda, A. Matsuo, K. Toide, Eur. J. Pharmacol. 1996, 305, 31-38.
15. Y. Shishido, M. Furushiro, S. Tanabe, S. Shibata, S. Hashimoto, T. Yokokura, Eur. J. Pharmacol. 1999, 372, 135-142.
16. P. Morain, J. L. Robin, G. De Nanteuil, R. Jochensemsen, V. Heidet, D. Guez, Br. J. Clin Pharmacol. 2000, 50, 350-359.
17. L. Polgar, Cell Mol. Life Sci. 2002, 59, 349-362.
18. L. Polgar, Curr. Cancer Drug Targets Curr. Med. Che.-Central Nervous System Agents 2002, 2, 251-257.
19. T. Tarrago, E. Sabido, M. J. Kogan, E. de Oliveira, E. Giralt, J. Pept. Sci. 2005, 11, 283-287.
20. T. Yanai, Y. Suzuki, M. Sato, Biosci. Biotechnol. Biochem. 2003, 67, 380-382.
21. R. Sorensen, E. Kildal, L. Stepaniak, A. H. Pripp, T. Sorhaug, Nahrung 2004, 48, 53-56.
22. Y. Tezuka, W. Fan, R. Kasimu, S. Kadota, Phytomedicine 1999, 6, 197-203.
23. Y. Z. Chen, S. Y. Chen Introduction of chemical methods in study of modernization of traditional Chinese medicines, Science Publishing, Beijing, 2003, pp. 1.
24. Pharmacopoeia of the People's Republic of China, Chemical Industry Publishing, 2000, Beijing.
25. X. Huang, L. Kong, X. Li, X. Chen, M. Guo, H. Zou, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2004, 812, 71-84.
26. T. Tarrago, S. Frutos, R. A. Rodriguez-Mias, E. Giralt, ChemBioChem 2006. 7, 827-833.
27. C. Liu, A. Tseng, Chinese Herbal Medicine, Modern Applications of Traditional Formulas, CRC Press. Boca Raton, USA, 2005.
28. S. Frutos, T. Tarrago, E. Giralt. Bioorg. Med. Lett. 2006, 16, 2677-2681.
29. P. L. Tsai, T. H. Tsai, Drug Metab. Dispos. 2004, 32, 405-412.
30. K. Yamamoto, H. Takase, K. Abe, Y. Saito, A. Suzuki, Nippo. Yakurigaku Zasshi. 1993, 101, 169-175.
31. Y. Wang, X. Yao, Y. H. Tan, J. Cardiovasc. Pharmacol. 1994, 23, 716-722.
32. Y. Kondo, F. Kondo, M. Asanuma, N. Ogawa, Neurochem. Res. 2000, 25, 205-209.
33. J. Xu, Y. Murakami, K. Matsumoto, M. Tohda, H. Watanabe, S. Zhang, Q. Yu, J. Shen, J. Ethnopharmacol. 2000, 73, 405-413.
34. X. Wang, D. Xing, W. Wang, F. Lei, H. Su, L. Du, Neurosc. Letters 2005, 379, 132-137.
35. I. Schulz, U. Zeitschel, T. Rudolph, D. Ruiz-Carrillo, J. U. Rahfeld, B. Gerhartz, V. Bigl, H. U. Demuth, S. Rossner, J. Neurochem. 2005, 94, 970-979.
36. X. Wang, R. Wang, D. Xing, H. Su, C. Ma, Y. Ding, L. Du, Life Sciences 2005, 77, 3058-3067.
37. X. Wang, D. Xing, W. Wang, F. Lei, H. Sui, L. Du. Neurosc. Letters 2005, 379, 132-137.
38. X. H. Zeng, X. J. Zeng, Y. Y. Li, Am. J. Cardiol. 2003, 92, 173-176.
39. W. Kong, J. Wei. , P. Abidi, M. Lin, S. Inaba, C. Li, Y. Wang, Z. Wang, S. Si, H. Pan, S. Wang, J. Wu, Y. Wang, Z. Li, J. Liu, J.-D. Jiang, Nature Med. 2004, 10, 1344-1351.