메뉴 건너뛰기




Volumn 11, Issue 5, 2005, Pages 283-287

Primary structure, recombinant expression and homology modelling of human brain prolyl oligopeptidase, an important therapeutic target in the treatment of neuropsychiatric diseases

Author keywords

Bipolar affective disorder; Neuropeptides; Prolyl oligopeptidase; Proteomics; Schizophrenia; Structural homology model

Indexed keywords

PROLYL ENDOPEPTIDASE; PROLYL ENDOPEPTIDASE INHIBITOR; S 17092 1; SUAM 14746; UNCLASSIFIED DRUG;

EID: 18844395154     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.676     Document Type: Article
Times cited : (18)

References (28)
  • 1
    • 0016612679 scopus 로고
    • Synthesis and conformational studies in solution of sequential copolypeptides. Poly(L-prolyl-L-α-phenylgiycyl-L-proline)
    • Palumbo M, Rodin RL, Goodman M. Synthesis and conformational studies in solution of sequential copolypeptides. Poly(L-prolyl-L-α-phenylgiycyl-L-proline). Biochemistry 1975; 14: 485-491.
    • (1975) Biochemistry , vol.14 , pp. 485-491
    • Palumbo, M.1    Rodin, R.L.2    Goodman, M.3
  • 2
    • 0014963513 scopus 로고
    • Conformational aspects of polypeptide structure. XXXI. Helical poly[(S)-thiazolidine-4-carboxylic acid] and poly[(S)-oxazolidine-4-carboxylic acid]. Theoretical results
    • Goodman M, Niu GCC, Su K. Conformational aspects of polypeptide structure. XXXI. Helical poly[(S)-thiazolidine-4-carboxylic acid] and poly[(S)-oxazolidine-4-carboxylic acid]. Theoretical results. J. Am. Chem. Soc. 1970; 92: 5219-5220.
    • (1970) J. Am. Chem. Soc. , vol.92 , pp. 5219-5220
    • Goodman, M.1    Niu, G.C.C.2    Su, K.3
  • 7
    • 0036178438 scopus 로고    scopus 로고
    • The prolyl oligopeptidase family
    • Polgar L. The prolyl oligopeptidase family. Cell. Mol. Life Sci. 2002; 59: 349-362.
    • (2002) Cell. Mol. Life Sci. , vol.59 , pp. 349-362
    • Polgar, L.1
  • 8
    • 0141690577 scopus 로고    scopus 로고
    • Structure-function of prolyl oligopeptidase and its role in neurological disorders
    • Polgar L. Structure-function of prolyl oligopeptidase and its role in neurological disorders. Curr. Med. Chem.-Central Nervous System Agents 2002; 2: 251-257.
    • (2002) Curr. Med. Chem.-Central Nervous System Agents , vol.2 , pp. 251-257
    • Polgar, L.1
  • 9
    • 0028802506 scopus 로고
    • Alterations in plasma prolyl endopeptidase activity in depression, mania, and schizophrenia: Effects of antidepressants, mood stabilizers, and antipsychotic drugs
    • Maes M, Goossens F, Scharpe S, Calabrese J, Desnyder R, Meltzer HY. Alterations in plasma prolyl endopeptidase activity in depression, mania, and schizophrenia: effects of antidepressants, mood stabilizers, and antipsychotic drugs. Psychiatry Res. 1995; 58: 217-225.
    • (1995) Psychiatry Res. , vol.58 , pp. 217-225
    • Maes, M.1    Goossens, F.2    Scharpe, S.3    Calabrese, J.4    Desnyder, R.5    Meltzer, H.Y.6
  • 10
    • 0031752029 scopus 로고    scopus 로고
    • Effects of psychological stress on serum prolyl endopeptidase and dipeptidyl peptidase IV activity in humans: Higher serum prolyl endopeptidase activity is related to stress-induced anxiety
    • Maes M, Goossens F, Lin A, De Meester I, Van Gastel A, Scharpe S. Effects of psychological stress on serum prolyl endopeptidase and dipeptidyl peptidase IV activity in humans: higher serum prolyl endopeptidase activity is related to stress-induced anxiety. Psychoneuroendocrinology 1998; 23: 485-495.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 485-495
    • Maes, M.1    Goossens, F.2    Lin, A.3    De Meester, I.4    Van Gastel, A.5    Scharpe, S.6
  • 12
    • 0032563162 scopus 로고    scopus 로고
    • Prolyl oligopeptidase: An unusual Β-propeller domain regulates proteolysis
    • Fulop V, Bocskei Z, Polgar L. Prolyl oligopeptidase: an unusual Β-propeller domain regulates proteolysis. Cell 1998; 94: 161-170.
    • (1998) Cell , vol.94 , pp. 161-170
    • Fulop, V.1    Bocskei, Z.2    Polgar, L.3
  • 14
    • 0028198616 scopus 로고
    • Molecular cloning and characterization of prolyl endopeptidase from human T cells
    • Shirasawa Y, Osawa T, Hirashima A. Molecular cloning and characterization of prolyl endopeptidase from human T cells. J. BioChem. (Tokyo) 1994; 115: 724-729.
    • (1994) J. BioChem. (Tokyo) , vol.115 , pp. 724-729
    • Shirasawa, Y.1    Osawa, T.2    Hirashima, A.3
  • 15
    • 0037870490 scopus 로고    scopus 로고
    • Schizophrenia: From phenomenology to neurobiology
    • Wong AH, Van Tol HH. Schizophrenia: from phenomenology to neurobiology. Neurosci. Biobehav. Rev. 2003; 27: 269-306.
    • (2003) Neurosci. Biobehav. Rev. , vol.27 , pp. 269-306
    • Wong, A.H.1    Van Tol, H.H.2
  • 16
    • 0037342917 scopus 로고    scopus 로고
    • Effect of S 17092, a novel prolyl endopeptidase inhibitor, on substance P and α-melanocyte-stimulating hormone breakdown in the rat brain
    • Bellemere G, Morain P, Vaudry H, Jegou S. Effect of S 17092, a novel prolyl endopeptidase inhibitor, on substance P and α-melanocyte-stimulating hormone breakdown in the rat brain. J. Neurochem. 2003; 84: 919-929.
    • (2003) J. Neurochem. , vol.84 , pp. 919-929
    • Bellemere, G.1    Morain, P.2    Vaudry, H.3    Jegou, S.4
  • 17
    • 0036163440 scopus 로고    scopus 로고
    • A prolyl endopeptidase-inhibiting benzofuran dimer from Polyozellus multiflex
    • Song KS, Raskin I. A prolyl endopeptidase-inhibiting benzofuran dimer from Polyozellus multiflex. J. Nat. Prod. 2002; 65: 76-78.
    • (2002) J. Nat. Prod. , vol.65 , pp. 76-78
    • Song, K.S.1    Raskin, I.2
  • 19
    • 0034003936 scopus 로고    scopus 로고
    • Substrate- and pH-dependent contribution of oxyanion binding site to the catalysis of prolyl oligopeptidase, a paradigm of the serine oligopeptidase family
    • Szeltner Z, Renner V, Polgar L. Substrate- and pH-dependent contribution of oxyanion binding site to the catalysis of prolyl oligopeptidase, a paradigm of the serine oligopeptidase family. Protein Sci. 2000; 9: 353-360.
    • (2000) Protein Sci. , vol.9 , pp. 353-360
    • Szeltner, Z.1    Renner, V.2    Polgar, L.3
  • 21
    • 1542571783 scopus 로고    scopus 로고
    • Electrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate binding
    • Szeltner Z, Rea D, Renner V, Juliano L, Fulop V, Polgar L. Electrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate binding. J. Biol. Chem. 2003; 278: 48 786-48 793.
    • (2003) J. Biol. Chem. , vol.278 , pp. 48786-48793
    • Szeltner, Z.1    Rea, D.2    Renner, V.3    Juliano, L.4    Fulop, V.5    Polgar, L.6
  • 24
    • 0029125636 scopus 로고
    • Increase in the septal vasopressin content by prolyl endopeptidase inhibitors in rats
    • Miura N, Shibata S, Watanabe S. Increase in the septal vasopressin content by prolyl endopeptidase inhibitors in rats. Neurosci. Lett. 1995; 196: 128-130.
    • (1995) Neurosci. Lett. , vol.196 , pp. 128-130
    • Miura, N.1    Shibata, S.2    Watanabe, S.3
  • 26
    • 0025117586 scopus 로고
    • Synthesis and inhibitory activity of acyl-peptidyl-prolinal derivatives toward post-proline cleaving enzyme as nootropic agents
    • Saito M, Hashimoto M, Kawaguchi N, Fukami H, Tanaka T, Higuchi N. Synthesis and inhibitory activity of acyl-peptidyl-prolinal derivatives toward post-proline cleaving enzyme as nootropic agents. J. Enzyme Inhib. 1990; 3: 163-178.
    • (1990) J. Enzyme Inhib. , vol.3 , pp. 163-178
    • Saito, M.1    Hashimoto, M.2    Kawaguchi, N.3    Fukami, H.4    Tanaka, T.5    Higuchi, N.6
  • 28
    • 2542543509 scopus 로고    scopus 로고
    • Molecular modeling of protein function regions
    • DeWeese-Scott C, Moult J. Molecular modeling of protein function regions. Proteins 2004; 55: 942-961.
    • (2004) Proteins , vol.55 , pp. 942-961
    • DeWeese-Scott, C.1    Moult, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.