-
1
-
-
0021923633
-
Efficacy of low-dose methotrexate in rheumatoid arthritis
-
Weinblatt ME, Coblyn JS, Fox DA, Fraser PA, Holdsworth DE, Glass DN, Trentham DE: Efficacy of low-dose methotrexate in rheumatoid arthritis. N Engl J Med 1985, 312:818-822.
-
(1985)
N Engl J Med
, vol.312
, pp. 818-822
-
-
Weinblatt, M.E.1
Coblyn, J.S.2
Fox, D.A.3
Fraser, P.A.4
Holdsworth, D.E.5
Glass, D.N.6
Trentham, D.E.7
-
2
-
-
0035985787
-
Molecular action of methotrexate in inflammatory diseases
-
Chan L, Cronstein BN: Molecular action of methotrexate in inflammatory diseases. Arthritis Res 2002, 4:266-273.
-
(2002)
Arthritis Res
, vol.4
, pp. 266-273
-
-
Chan, L.1
Cronstein, B.N.2
-
3
-
-
0032802514
-
Urinary adenosine and aminoimidazolcarboxamide excretion in methotrexatetreated patients with psoriasis
-
Baggott JE, Morgan SL, Sams WM, Linden J: Urinary adenosine and aminoimidazolcarboxamide excretion in methotrexatetreated patients with psoriasis. Arch Dermatol 1999, 135:813-817.
-
(1999)
Arch Dermatol
, vol.135
, pp. 813-817
-
-
Baggott, J.E.1
Morgan, S.L.2
Sams, W.M.3
Linden, J.4
-
4
-
-
0031452023
-
Adenosine plasma levels after low-dose methotrexate administration
-
Laghi Pasini F, Capecchi PL, Di Perri T: Adenosine plasma levels after low-dose methotrexate administration. J Rheumatol 1997, 24:2492-2493.
-
(1997)
J Rheumatol
, vol.24
, pp. 2492-2493
-
-
Laghi Pasini, F.1
Capecchi, P.L.2
Di Perri, T.3
-
5
-
-
0027983055
-
Adenosine, an endogenous anti-inflammatory agent
-
Cronstein BN: Adenosine, an endogenous anti-inflammatory agent. J Appl Physiol 1994, 76:5-13.
-
(1994)
J Appl Physiol
, vol.76
, pp. 5-13
-
-
Cronstein, B.N.1
-
6
-
-
0031022361
-
Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis
-
Eigler A, Greten TF, Sinha B, Haslberger C, Sullivan GW, Endres S: Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis. Scand J Immunol 1997, 45 132-139.
-
(1997)
Scand J Immunol
, vol.45
, pp. 132-139
-
-
Eigler, A.1
Greten, T.F.2
Sinha, B.3
Haslberger, C.4
Sullivan, G.W.5
Endres, S.6
-
7
-
-
0037453358
-
The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide, is protective in two murine models of colitis
-
Mabley J, Soriano F, Pacher P, Hasko G, Marton A, Wallace R, Salzman A, Szabo C: The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide, is protective in two murine models of colitis. Eur J Pharmacol 2003, 466 323-329.
-
(2003)
Eur J Pharmacol
, vol.466
, pp. 323-329
-
-
Mabley, J.1
Soriano, F.2
Pacher, P.3
Hasko, G.4
Marton, A.5
Wallace, R.6
Salzman, A.7
Szabo, C.8
-
8
-
-
0347093665
-
Adenosine A2A receptor agonists as anti-inflammatory agents
-
Sullivan GW: Adenosine A2A receptor agonists as anti-inflammatory agents. Curr Opin Investig Drugs 2003, 4:1313-1319.
-
(2003)
Curr Opin Investig Drugs
, vol.4
, pp. 1313-1319
-
-
Sullivan, G.W.1
-
9
-
-
0037207972
-
Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68
-
Montesinos MC, Desai A, Delano D, Chen JF, Fink JS, Jacobson MA, Cronstein BN: Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68. Arthritis Rheum 2003, 48:240-247.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 240-247
-
-
Montesinos, M.C.1
Desai, A.2
Delano, D.3
Chen, J.F.4
Fink, J.S.5
Jacobson, M.A.6
Cronstein, B.N.7
-
10
-
-
0031691973
-
Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists
-
Szabo C, Scott GS, Virag L, Egnaczyk G, Salzman AL, Shanley TP, Hasko G: Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists Br J Pharmacol 1998, 125:379-387.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 379-387
-
-
Szabo, C.1
Scott, G.S.2
Virag, L.3
Egnaczyk, G.4
Salzman, A.L.5
Shanley, T.P.6
Hasko, G.7
-
11
-
-
15044343787
-
The antiinflammatory effect of A3 adenosine receptor agonists in murine autoimmune arthritis models
-
Baharav E, Bar-Yehuda S, Madi L, Silberman D, Rath-Wolfson L, Halpren M, Ochaion A, Weinberger A, Fishman P: The antiinflammatory effect of A3 adenosine receptor agonists in murine autoimmune arthritis models. J Rheumatol 2005, 32:469-476.
-
(2005)
J Rheumatol
, vol.32
, pp. 469-476
-
-
Baharav, E.1
Bar-Yehuda, S.2
Madi, L.3
Silberman, D.4
Rath-Wolfson, L.5
Halpren, M.6
Ochaion, A.7
Weinberger, A.8
Fishman, P.9
-
12
-
-
70449564383
-
The PI3K-NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IBMECA in adjuvant induced arthritis
-
Fishman P, Bar-Yehuda S, Madi L, Rath-Wolfson L, Ochaion A, Cohen S, Baharav E: The PI3K-NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IBMECA in adjuvant induced arthritis. Arthritis Res Ther 2006, 8:R33.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Fishman, P.1
Bar-Yehuda, S.2
Madi, L.3
Rath-Wolfson, L.4
Ochaion, A.5
Cohen, S.6
Baharav, E.7
-
13
-
-
4444247043
-
Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells
-
Gessi S, Cattabriga E, Avitabile A, Gafa' R, Lanza G, Cavazzini L, Bianchi N, Gambari R, Feo C, Liboni A, et al.: Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells. Clin Cancer Res 2004, 10:5895-5901.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5895-5901
-
-
Gessi, S.1
Cattabriga, E.2
Avitabile, A.3
Gafa', R.4
Lanza, G.5
Cavazzini, L.6
Bianchi, N.7
Gambari, R.8
Feo, C.9
Liboni, A.10
-
14
-
-
6344278503
-
Tolerability, pharmacokinetics and concentration-dependent hemodynamic effects of oral CF101, an A3 adenosine receptor agonist, in healthy young men
-
van Troostenburg AR, Clark EV, Carey WD, Warrington SJ, Kerns WD, Cohn I, Silverman MH, Bar-Yehuda S, Fong KL, Fishman P: Tolerability, pharmacokinetics and concentration-dependent hemodynamic effects of oral CF101, an A3 adenosine receptor agonist, in healthy young men. Int J Clin Pharmacol Ther 2004, 42:534-542.
-
(2004)
Int J Clin Pharmacol Ther
, vol.42
, pp. 534-542
-
-
van Troostenburg, A.R.1
Clark, E.V.2
Carey, W.D.3
Warrington, S.J.4
Kerns, W.D.5
Cohn, I.6
Silverman, M.H.7
Bar-Yehuda, S.8
Fong, K.L.9
Fishman, P.10
-
15
-
-
70350504819
-
Targeting the A3 adenosine receptor to combat arthritis: Early phase II study in RA patients treated with CF101
-
USA Hoboken, NJ: John Wiley & Sons;
-
Nahir MA, Reitblat T, Molad Y, Rosner I, Mader R, Caspi D, Tishler M, Langevitz P, Rubinow A, Green L, et al.: Targeting the A3 adenosine receptor to combat arthritis: Early phase II study in RA patients treated with CF101. In Proceedings of the 2005 ACR/ARHP Annual Scientific Meeting; 12-17 November 2005; San Diego, CA, USA Hoboken, NJ: John Wiley & Sons; 2005:1235.
-
(2005)
Proceedings of the 2005 ACR/ARHP Annual Scientific Meeting; 12-17 November 2005; San Diego, CA
, pp. 1235
-
-
Nahir, M.A.1
Reitblat, T.2
Molad, Y.3
Rosner, I.4
Mader, R.5
Caspi, D.6
Tishler, M.7
Langevitz, P.8
Rubinow, A.9
Green, L.10
-
16
-
-
30844434332
-
Real-world effectiveness of select biologic and DMARD monotherapy and combination therapy in the treatment of rheumatoid arthritis: Results from the RADIUS observational registry
-
Weaver AL, Lautzenheiser RL, Schiff MH, Gibofsky A, Perruquet JL, Luetkemeyer J, Paulus HE, Xia HA, Leff JA: Real-world effectiveness of select biologic and DMARD monotherapy and combination therapy in the treatment of rheumatoid arthritis: Results from the RADIUS observational registry. Curr Med Res Opin 2006, 22:185-198.
-
(2006)
Curr Med Res Opin
, vol.22
, pp. 185-198
-
-
Weaver, A.L.1
Lautzenheiser, R.L.2
Schiff, M.H.3
Gibofsky, A.4
Perruquet, J.L.5
Luetkemeyer, J.6
Paulus, H.E.7
Xia, H.A.8
Leff, J.A.9
-
17
-
-
0010105962
-
Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates
-
Allegra CJ, Drake JC, Jolivet J, Chabner BA: Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates. Proc Natl Acad Sci USA 1985, 82:4881-4885.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 4881-4885
-
-
Allegra, C.J.1
Drake, J.C.2
Jolivet, J.3
Chabner, B.A.4
-
18
-
-
0023280787
-
Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate
-
Allegra CJ, Hoang K, Yeh GC, Drake JC, Baram J: Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate. J Biol Chem 1987, 262:13520-13526.
-
(1987)
J Biol Chem
, vol.262
, pp. 13520-13526
-
-
Allegra, C.J.1
Hoang, K.2
Yeh, G.C.3
Drake, J.C.4
Baram, J.5
-
19
-
-
0022637441
-
Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5′-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide
-
Baggott JE, Vaughn WH, Hudson BB: Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5′-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide. Biochem J 1986, 236:193-200.
-
(1986)
Biochem J
, vol.236
, pp. 193-200
-
-
Baggott, J.E.1
Vaughn, W.H.2
Hudson, B.B.3
-
20
-
-
0036841404
-
Regulation of the A3 adenosine receptor gene in vascular smooth muscle cells: Role of a cAMP and GATA element
-
Yaar R, Cataldo LM, Tzatsos A, Francis CE, Zhao Z, Ravid K: Regulation of the A3 adenosine receptor gene in vascular smooth muscle cells: Role of a cAMP and GATA element. Mol Pharmacol 2002, 62:1167-1176.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1167-1176
-
-
Yaar, R.1
Cataldo, L.M.2
Tzatsos, A.3
Francis, C.E.4
Zhao, Z.5
Ravid, K.6
-
21
-
-
0037178739
-
Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptor
-
Black RG Jr, Guo Y, Ge ZD, Murphree SS, Prabhu SD, Jones WK, Bolli R, Auchampach JA: Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptor. Circ Res 2002, 91:165-172.
-
(2002)
Circ Res
, vol.91
, pp. 165-172
-
-
Black Jr, R.G.1
Guo, Y.2
Ge, Z.D.3
Murphree, S.S.4
Prabhu, S.D.5
Jones, W.K.6
Bolli, R.7
Auchampach, J.A.8
-
22
-
-
0031760622
-
Cardiac myocytes rendered ischemia resistant by expressing the human adenosine A1 or A3 receptor
-
Dougherty C, Barucha J, Schofield PR, Jacobson KA, Liang BT: Cardiac myocytes rendered ischemia resistant by expressing the human adenosine A1 or A3 receptor. FASEB J 1998, 12:1785-1792.
-
(1998)
FASEB J
, vol.12
, pp. 1785-1792
-
-
Dougherty, C.1
Barucha, J.2
Schofield, P.R.3
Jacobson, K.A.4
Liang, B.T.5
-
23
-
-
0038481982
-
Pharmacology and Therapeutic application of A1 adenosine receptor ligands
-
Dhalla AK, Shryock JC, Shreeniwas R, Belardinelli L: Pharmacology and Therapeutic application of A1 adenosine receptor ligands. Curr Top Med Chem 2003, 3:369-385.
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 369-385
-
-
Dhalla, A.K.1
Shryock, J.C.2
Shreeniwas, R.3
Belardinelli, L.4
-
24
-
-
0142211261
-
A3 adenosine receptor activation in melanoma cells: Association between receptor fate and tumor growth inhibition
-
Madi L, Bar-Yehuda S, Barer F, Ardon E, Ochaion A, Fishman P: A3 adenosine receptor activation in melanoma cells: Association between receptor fate and tumor growth inhibition. J Biol Chem 2003, 278:42121-42130.
-
(2003)
J Biol Chem
, vol.278
, pp. 42121-42130
-
-
Madi, L.1
Bar-Yehuda, S.2
Barer, F.3
Ardon, E.4
Ochaion, A.5
Fishman, P.6
-
25
-
-
0042807352
-
Targeting the A3 adenosine receptor for cancer therapy: Inhibition of Prostate carcinoma cell growth by A3AR agonist
-
Fishman P, Bar-Yehuda S, Ardon E, Rath-Wolfson L, Barrer F, Ochaion A, Madi L: Targeting the A3 adenosine receptor for cancer therapy: inhibition of Prostate carcinoma cell growth by A3AR agonist. Anticancer Res 2003, 23:2077-2083.
-
(2003)
Anticancer Res
, vol.23
, pp. 2077-2083
-
-
Fishman, P.1
Bar-Yehuda, S.2
Ardon, E.3
Rath-Wolfson, L.4
Barrer, F.5
Ochaion, A.6
Madi, L.7
-
26
-
-
0035209620
-
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
-
Fredholm BB, Ijzerman AP, Jacobson KA, Klotz KN, Linden J: International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 2001, 53:527-552.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 527-552
-
-
Fredholm, B.B.1
Ijzerman, A.P.2
Jacobson, K.A.3
Klotz, K.N.4
Linden, J.5
-
27
-
-
22144475862
-
Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma
-
Schlotzer-Schrehardt U, Zenkel M, Decking U, Haubs D, Kruse FE, Junemann A, Coca-Prados M, Naumann GO: Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma Invest Ophthalmol Vis Sci 2005, 46:2023-2034.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 2023-2034
-
-
Schlotzer-Schrehardt, U.1
Zenkel, M.2
Decking, U.3
Haubs, D.4
Kruse, F.E.5
Junemann, A.6
Coca-Prados, M.7
Naumann, G.O.8
-
28
-
-
0031132545
-
Adenosine A3 receptor expression and function in eosinophils
-
Walker BA, Jacobson MA, Knight DA, Salvatore CA, Weir T, Zhou D, Bai TR: Adenosine A3 receptor expression and function in eosinophils. Am J Respir Cell Mol Biol 1997, 16:531-537.
-
(1997)
Am J Respir Cell Mol Biol
, vol.16
, pp. 531-537
-
-
Walker, B.A.1
Jacobson, M.A.2
Knight, D.A.3
Salvatore, C.A.4
Weir, T.5
Zhou, D.6
Bai, T.R.7
-
29
-
-
10744223679
-
Expression of A3 adenosine receptors in human lymphocytes: Up-regulation in T cell activation
-
Gessi S, Varani K, Merighi S, Cattabriga E, Avitabile A, Gavioli R, Fortini C, Leung E, Mac Lennan S, Borea PA: Expression of A3 adenosine receptors in human lymphocytes: Up-regulation in T cell activation. Mol Pharmacol 2004, 65:711-719.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 711-719
-
-
Gessi, S.1
Varani, K.2
Merighi, S.3
Cattabriga, E.4
Avitabile, A.5
Gavioli, R.6
Fortini, C.7
Leung, E.8
Mac Lennan, S.9
Borea, P.A.10
|