-
1
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon D.J., Godolphin W., Jones L.A., Holt J.A., Wong S.G., Keith D.E., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244 4905 (1989) 707-712
-
(1989)
Science
, vol.244
, Issue.4905
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
-
2
-
-
0026545620
-
(c-erbB-2) oncogene is frequently amplified in in situ carcinomas of the breast
-
Liu E., Thor A., He M., Barcos M., Ljung B.M., Benz C., et al. (c-erbB-2) oncogene is frequently amplified in in situ carcinomas of the breast. Oncogene 7 (1992) 1027-1034
-
(1992)
Oncogene
, vol.7
, pp. 1027-1034
-
-
Liu, E.1
Thor, A.2
He, M.3
Barcos, M.4
Ljung, B.M.5
Benz, C.6
-
3
-
-
34447306848
-
Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer
-
Valabrega G., Montemurro F., and Aglietta M. Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer. Ann Oncol (2007)
-
(2007)
Ann Oncol
-
-
Valabrega, G.1
Montemurro, F.2
Aglietta, M.3
-
4
-
-
33846627223
-
Progress and new standards of care in the management of HER-2 positive breast cancer
-
Demonty G., Bernard-Marty C., Puglisi F., Mancini I., and Piccart M. Progress and new standards of care in the management of HER-2 positive breast cancer. Eur J Cancer 43 3 (2007) 497-509
-
(2007)
Eur J Cancer
, vol.43
, Issue.3
, pp. 497-509
-
-
Demonty, G.1
Bernard-Marty, C.2
Puglisi, F.3
Mancini, I.4
Piccart, M.5
-
5
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon D.J., Leyland-Jones B., Shak S., Fuchs H., Paton V., Bajamonde A., et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344 11 (2001) 783-792
-
(2001)
N Engl J Med
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
-
6
-
-
22344446208
-
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group
-
Marty M., Cognetti F., Maraninchi D., Snyder R., Mauriac L., Tubiana-Hulin M., et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group. J Clin Oncol 23 19 (2005) 4265-4274
-
(2005)
J Clin Oncol
, vol.23
, Issue.19
, pp. 4265-4274
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
Snyder, R.4
Mauriac, L.5
Tubiana-Hulin, M.6
-
7
-
-
0031932303
-
Human HER-2/neu protein immunization circumvents tolerance to rat neu: a vaccine strategy for 'self' tumour antigens
-
Disis M.L., Shiota F.M., and Cheever M.A. Human HER-2/neu protein immunization circumvents tolerance to rat neu: a vaccine strategy for 'self' tumour antigens. Immunology 93 2 (1998) 192-199
-
(1998)
Immunology
, vol.93
, Issue.2
, pp. 192-199
-
-
Disis, M.L.1
Shiota, F.M.2
Cheever, M.A.3
-
8
-
-
0033048807
-
Generation of immunity to the HER-2/neu oncogenic protein in patients with breast and ovarian cancer using a peptide-based vaccine
-
Disis M.L., Grabstein K.H., Sleath P.R., and Cheever M.A. Generation of immunity to the HER-2/neu oncogenic protein in patients with breast and ovarian cancer using a peptide-based vaccine. Clin Cancer Res 5 6 (1999) 1289-1297
-
(1999)
Clin Cancer Res
, vol.5
, Issue.6
, pp. 1289-1297
-
-
Disis, M.L.1
Grabstein, K.H.2
Sleath, P.R.3
Cheever, M.A.4
-
9
-
-
0037089223
-
Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu-overexpressing cancers
-
Disis M.L., Rinn K., Knutson K.L., Davis D., Caron D., Dela R.C., et al. Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu-overexpressing cancers. Blood 99 8 (2002) 2845-2850
-
(2002)
Blood
, vol.99
, Issue.8
, pp. 2845-2850
-
-
Disis, M.L.1
Rinn, K.2
Knutson, K.L.3
Davis, D.4
Caron, D.5
Dela, R.C.6
-
10
-
-
0036605567
-
Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines
-
Disis M.L., Gooley T.A., Rinn K., Davis D., Piepkorn M., Cheever M.A., et al. Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines. J Clin Oncol 20 11 (2002) 2624-2632
-
(2002)
J Clin Oncol
, vol.20
, Issue.11
, pp. 2624-2632
-
-
Disis, M.L.1
Gooley, T.A.2
Rinn, K.3
Davis, D.4
Piepkorn, M.5
Cheever, M.A.6
-
11
-
-
4544252430
-
Humoral epitope-spreading following immunization with a HER-2/neu peptide based vaccine in cancer patients
-
Disis M.L., Goodell V., Schiffman K., and Knutson K.L. Humoral epitope-spreading following immunization with a HER-2/neu peptide based vaccine in cancer patients. J Clin Immunol 24 5 (2004) 571-578
-
(2004)
J Clin Immunol
, vol.24
, Issue.5
, pp. 571-578
-
-
Disis, M.L.1
Goodell, V.2
Schiffman, K.3
Knutson, K.L.4
-
12
-
-
3042745485
-
Effect of dose on immune response in patients vaccinated with an her-2/neu intracellular domain protein-based vaccine
-
Disis M.L., Schiffman K., Guthrie K., Salazar L.G., Knutson K.L., Goodell V., et al. Effect of dose on immune response in patients vaccinated with an her-2/neu intracellular domain protein-based vaccine. J Clin Oncol 22 10 (2004) 1916-1925
-
(2004)
J Clin Oncol
, vol.22
, Issue.10
, pp. 1916-1925
-
-
Disis, M.L.1
Schiffman, K.2
Guthrie, K.3
Salazar, L.G.4
Knutson, K.L.5
Goodell, V.6
-
13
-
-
0345060456
-
Immunization of cancer patients with HER-2/neu-derived peptides demonstrating high-affinity binding to multiple class II alleles
-
Salazar L.G., Fikes J., Southwood S., Ishioka G., Knutson K.L., Gooley T.A., et al. Immunization of cancer patients with HER-2/neu-derived peptides demonstrating high-affinity binding to multiple class II alleles. Clin Cancer Res 9 15 (2003) 5559-5565
-
(2003)
Clin Cancer Res
, vol.9
, Issue.15
, pp. 5559-5565
-
-
Salazar, L.G.1
Fikes, J.2
Southwood, S.3
Ishioka, G.4
Knutson, K.L.5
Gooley, T.A.6
-
14
-
-
0036098003
-
Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity
-
Knutson K.L., Schiffman K., Cheever M.A., and Disis M.L. Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity. Clin Cancer Res 8 5 (2002) 1014-1018
-
(2002)
Clin Cancer Res
, vol.8
, Issue.5
, pp. 1014-1018
-
-
Knutson, K.L.1
Schiffman, K.2
Cheever, M.A.3
Disis, M.L.4
-
15
-
-
0037285797
-
Pilot study of an HLA-A2 peptide vaccine using flt3 ligand as a systemic vaccine adjuvant
-
McNeel D.G., Knutson K.L., Schiffman K., Davis D.R., Caron D., and Disis M.L. Pilot study of an HLA-A2 peptide vaccine using flt3 ligand as a systemic vaccine adjuvant. J Clin Immunol 23 1 (2003) 62-72
-
(2003)
J Clin Immunol
, vol.23
, Issue.1
, pp. 62-72
-
-
McNeel, D.G.1
Knutson, K.L.2
Schiffman, K.3
Davis, D.R.4
Caron, D.5
Disis, M.L.6
-
16
-
-
27144464759
-
Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients
-
Peoples G.E., Gurney J.M., Hueman M.T., Woll M.M., Ryan G.B., Storrer C.E., et al. Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients. J Clin Oncol 23 30 (2005) 7536-7545
-
(2005)
J Clin Oncol
, vol.23
, Issue.30
, pp. 7536-7545
-
-
Peoples, G.E.1
Gurney, J.M.2
Hueman, M.T.3
Woll, M.M.4
Ryan, G.B.5
Storrer, C.E.6
-
17
-
-
27144559991
-
Phase I clinical trial of a HER-2/neu peptide (E75) vaccine for the prevention of prostate-specific antigen recurrence in high-risk prostate cancer patients
-
Hueman M.T., Dehqanzada Z.A., Novak T.E., Gurney J.M., Woll M.M., Ryan G.B., et al. Phase I clinical trial of a HER-2/neu peptide (E75) vaccine for the prevention of prostate-specific antigen recurrence in high-risk prostate cancer patients. Clin Cancer Res 11 20 (2005) 7470-7479
-
(2005)
Clin Cancer Res
, vol.11
, Issue.20
, pp. 7470-7479
-
-
Hueman, M.T.1
Dehqanzada, Z.A.2
Novak, T.E.3
Gurney, J.M.4
Woll, M.M.5
Ryan, G.B.6
-
18
-
-
0036847689
-
Toxicity, immunogenicity, and induction of E75-specific tumor-lytic CTLs by HER-2 peptide E75 (369-377) combined with granulocyte macrophage colony-stimulating factor in HLA-A2+ patients with metastatic breast and ovarian cancer
-
Murray J.L., Gillogly M.E., Przepiorka D., Brewer H., Ibrahim N.K., Booser D.J., et al. Toxicity, immunogenicity, and induction of E75-specific tumor-lytic CTLs by HER-2 peptide E75 (369-377) combined with granulocyte macrophage colony-stimulating factor in HLA-A2+ patients with metastatic breast and ovarian cancer. Clin Cancer Res 8 11 (2002) 3407-3418
-
(2002)
Clin Cancer Res
, vol.8
, Issue.11
, pp. 3407-3418
-
-
Murray, J.L.1
Gillogly, M.E.2
Przepiorka, D.3
Brewer, H.4
Ibrahim, N.K.5
Booser, D.J.6
-
19
-
-
0032213456
-
Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptide-specific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors
-
Zaks T.Z., and Rosenberg S.A. Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptide-specific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors. Cancer Res 58 21 (1998) 4902-4908
-
(1998)
Cancer Res
, vol.58
, Issue.21
, pp. 4902-4908
-
-
Zaks, T.Z.1
Rosenberg, S.A.2
-
20
-
-
16444377935
-
CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer
-
Daniel D., Chiu C., Giraudo E., Inoue M., Mizzen L.A., Chu N.R., et al. CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer. Cancer Res 65 5 (2005) 2018-2025
-
(2005)
Cancer Res
, vol.65
, Issue.5
, pp. 2018-2025
-
-
Daniel, D.1
Chiu, C.2
Giraudo, E.3
Inoue, M.4
Mizzen, L.A.5
Chu, N.R.6
-
21
-
-
17944379652
-
Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma
-
Dudley M.E., Wunderlich J., Nishimura M.I., Yu D., Yang J.C., Topalian S.L., et al. Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma. J Immunother 24 4 (2001) 363-373
-
(2001)
J Immunother
, vol.24
, Issue.4
, pp. 363-373
-
-
Dudley, M.E.1
Wunderlich, J.2
Nishimura, M.I.3
Yu, D.4
Yang, J.C.5
Topalian, S.L.6
-
22
-
-
0036569592
-
Human CD4+ effector T cells mediate indirect interleukin-12- and interferon-gamma-dependent suppression of autologous HLA-negative lung tumor xenografts in severe combined immunodeficient mice
-
Egilmez N.K., Hess S.D., Chen F.A., Takita H., Conway T.F., and Bankert R.B. Human CD4+ effector T cells mediate indirect interleukin-12- and interferon-gamma-dependent suppression of autologous HLA-negative lung tumor xenografts in severe combined immunodeficient mice. Cancer Res 62 9 (2002) 2611-2617
-
(2002)
Cancer Res
, vol.62
, Issue.9
, pp. 2611-2617
-
-
Egilmez, N.K.1
Hess, S.D.2
Chen, F.A.3
Takita, H.4
Conway, T.F.5
Bankert, R.B.6
-
23
-
-
0021826670
-
Therapy of disseminated murine leukemia with cyclophosphamide and immune Lyt-1+,2- T cells. Tumor eradication does not require participation of cytotoxic T cells
-
Greenberg P.D., Kern D.E., and Cheever M.A. Therapy of disseminated murine leukemia with cyclophosphamide and immune Lyt-1+,2- T cells. Tumor eradication does not require participation of cytotoxic T cells. J Exp Med 161 5 (1985) 1122-1134
-
(1985)
J Exp Med
, vol.161
, Issue.5
, pp. 1122-1134
-
-
Greenberg, P.D.1
Kern, D.E.2
Cheever, M.A.3
-
24
-
-
0036134856
-
Cutting edge: IL-10-producing CD4+ T cells mediate tumor rejection
-
[(GENERIC) Ref Type: Generic]
-
Segal B.M., Glass D.D., and Shevach E.M. Cutting edge: IL-10-producing CD4+ T cells mediate tumor rejection. J Immunol 168 1-4 (2002) [(GENERIC) Ref Type: Generic]
-
(2002)
J Immunol
, vol.168
, Issue.1-4
-
-
Segal, B.M.1
Glass, D.D.2
Shevach, E.M.3
-
25
-
-
0037432787
-
Requirement for CD4 T cell help in generating functional CD8 T cell memory
-
Shedlock D.J., and Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300 5617 (2003) 337-339
-
(2003)
Science
, vol.300
, Issue.5617
, pp. 337-339
-
-
Shedlock, D.J.1
Shen, H.2
-
26
-
-
0037432776
-
Defective CD8 T cell memory following acute infection without CD4 T cell help
-
Sun J.C., and Bevan M.J. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300 5617 (2003) 339-342
-
(2003)
Science
, vol.300
, Issue.5617
, pp. 339-342
-
-
Sun, J.C.1
Bevan, M.J.2
-
27
-
-
0042346039
-
HER-2 DNA and protein vaccines containing potent Th cell epitopes induce distinct protective and therapeutic antitumor responses in HER-2 transgenic mice
-
Renard V., Sonderbye L., Ebbehoj K., Rasmussen P.B., Gregorius K., Gottschalk T., et al. HER-2 DNA and protein vaccines containing potent Th cell epitopes induce distinct protective and therapeutic antitumor responses in HER-2 transgenic mice. J Immunol 171 3 (2003) 1588-1595
-
(2003)
J Immunol
, vol.171
, Issue.3
, pp. 1588-1595
-
-
Renard, V.1
Sonderbye, L.2
Ebbehoj, K.3
Rasmussen, P.B.4
Gregorius, K.5
Gottschalk, T.6
-
28
-
-
33847038268
-
Generation of autoreactive CTL by tumour vaccines containing foreign T helper epitopes
-
Steinaa L., Rasmussen P.B., Rygaard J., Mouritsen S., and Gautam A. Generation of autoreactive CTL by tumour vaccines containing foreign T helper epitopes. Scand J Immunol 65 3 (2007) 240-248
-
(2007)
Scand J Immunol
, vol.65
, Issue.3
, pp. 240-248
-
-
Steinaa, L.1
Rasmussen, P.B.2
Rygaard, J.3
Mouritsen, S.4
Gautam, A.5
-
29
-
-
21244435520
-
Linked foreign T-cell help activates self-reactive CTL and inhibits tumor growth
-
Steinaa L., Rasmussen P.B., Wegener A.M., Sonderbye L., Leach D.R., Rygaard J., et al. Linked foreign T-cell help activates self-reactive CTL and inhibits tumor growth. J Immunol 175 1 (2005) 329-334
-
(2005)
J Immunol
, vol.175
, Issue.1
, pp. 329-334
-
-
Steinaa, L.1
Rasmussen, P.B.2
Wegener, A.M.3
Sonderbye, L.4
Leach, D.R.5
Rygaard, J.6
-
30
-
-
0035478849
-
Active vaccination against IL-5 bypasses immunological tolerance and ameliorates experimental asthma
-
Hertz M., Mahalingam S., Dalum I., Klysner S., Mattes J., Neisig A., et al. Active vaccination against IL-5 bypasses immunological tolerance and ameliorates experimental asthma. J Immunol 167 7 (2001) 3792-3799
-
(2001)
J Immunol
, vol.167
, Issue.7
, pp. 3792-3799
-
-
Hertz, M.1
Mahalingam, S.2
Dalum, I.3
Klysner, S.4
Mattes, J.5
Neisig, A.6
-
31
-
-
0033018740
-
Therapeutic antibodies elicited by immunization against TNF-alpha
-
Dalum I., Butler D.M., Jensen M.R., Hindersson P., Steinaa L., Waterston A.M., et al. Therapeutic antibodies elicited by immunization against TNF-alpha. Nat Biotechnol 17 7 (1999) 666-669
-
(1999)
Nat Biotechnol
, vol.17
, Issue.7
, pp. 666-669
-
-
Dalum, I.1
Butler, D.M.2
Jensen, M.R.3
Hindersson, P.4
Steinaa, L.5
Waterston, A.M.6
-
32
-
-
0024796883
-
Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells
-
Panina-Bordignon P., Tan A., Termijtelen A., Demotz S., Corradin G., and Lanzavecchia A. Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur J Immunol 19 12 (1989) 2237-2242
-
(1989)
Eur J Immunol
, vol.19
, Issue.12
, pp. 2237-2242
-
-
Panina-Bordignon, P.1
Tan, A.2
Termijtelen, A.3
Demotz, S.4
Corradin, G.5
Lanzavecchia, A.6
-
33
-
-
0023713558
-
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
-
Muller W.J., Sinn E., Pattengale P.K., Wallace R., and Leder P. Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 54 1 (1988) 105-115
-
(1988)
Cell
, vol.54
, Issue.1
, pp. 105-115
-
-
Muller, W.J.1
Sinn, E.2
Pattengale, P.K.3
Wallace, R.4
Leder, P.5
-
34
-
-
0026033441
-
Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex
-
Kensil C.R., Patel U., Lennick M., and Marciani D. Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. J Immunol 146 2 (1991) 431-437
-
(1991)
J Immunol
, vol.146
, Issue.2
, pp. 431-437
-
-
Kensil, C.R.1
Patel, U.2
Lennick, M.3
Marciani, D.4
-
35
-
-
85013689055
-
Immunopotentiators in modern vaccines
-
Kensil C.R., Schijns V., and O'Hagan D. (Eds), Elsevier, London
-
Immunopotentiators in modern vaccines. In: Kensil C.R., Schijns V., and O'Hagan D. (Eds). Immunomodulatory adjuvants from Quillaja saponaria (2006), Elsevier, London 109-122
-
(2006)
Immunomodulatory adjuvants from Quillaja saponaria
, pp. 109-122
-
-
-
36
-
-
0022630369
-
Long-term follow-up of general immune competence in breast cancer. II. Sequential pre- and post-treatment levels: a 10 year study
-
Shukla H.S., Hughes L.E., Whitehead R.H., and Newcombe R.G. Long-term follow-up of general immune competence in breast cancer. II. Sequential pre- and post-treatment levels: a 10 year study. Cancer Immunol Immunother 21 1 (1986) 6-11
-
(1986)
Cancer Immunol Immunother
, vol.21
, Issue.1
, pp. 6-11
-
-
Shukla, H.S.1
Hughes, L.E.2
Whitehead, R.H.3
Newcombe, R.G.4
-
37
-
-
0030446572
-
Structure/function studies on QS-21, a unique immunological adjuvant from Quillaja saponaria
-
Kensil C.R., Soltysik S., Wheeler D.A., and Wu J.Y. Structure/function studies on QS-21, a unique immunological adjuvant from Quillaja saponaria. Adv Exp Med Biol 404 (1996) 165-172
-
(1996)
Adv Exp Med Biol
, vol.404
, pp. 165-172
-
-
Kensil, C.R.1
Soltysik, S.2
Wheeler, D.A.3
Wu, J.Y.4
-
38
-
-
0035339880
-
High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801
-
Kirkwood J.M., Ibrahim J.G., Sosman J.A., Sondak V.K., Agarwala S.S., Ernstoff M.S., et al. High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J Clin Oncol 19 9 (2001) 2370-2380
-
(2001)
J Clin Oncol
, vol.19
, Issue.9
, pp. 2370-2380
-
-
Kirkwood, J.M.1
Ibrahim, J.G.2
Sosman, J.A.3
Sondak, V.K.4
Agarwala, S.S.5
Ernstoff, M.S.6
-
39
-
-
0031775979
-
A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: report of a pilot clinical trial
-
Gonzalez G., Crombet T., Catala M., Mirabal V., Hernandez J.C., Gonzalez Y., et al. A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: report of a pilot clinical trial. Ann Oncol 9 4 (1998) 431-435
-
(1998)
Ann Oncol
, vol.9
, Issue.4
, pp. 431-435
-
-
Gonzalez, G.1
Crombet, T.2
Catala, M.3
Mirabal, V.4
Hernandez, J.C.5
Gonzalez, Y.6
|