Nanoparticle-based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigen

Journal of Acquired Immune Deficiency Syndromes

Volumn 46, Issue 2, 2007, Pages 231-237

  Tang, Shixing ^a   Zhao, Jiangqin ^a   Storhoff, James J ^b   Norris, Philip J ^c   Little, Richard F ^d   Yarchoan, Robert ^d   Stramer, Susan L ^e   Patno, Tim ^b   Domanus, Marc ^b   Dhar, Arindam ^a,d   Mirkin, Chad A ^f   Hewlett, Indira K ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b Nanosphere Inc   (United States)

^c BLOOD SYSTEMS RESEARCH INSTITUTE   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e AMERICAN RED CROSS   (United States)

^f NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Biobarcode; Detection; HIV 1; Nanoparticle; p24 antigen

Indexed keywords

ANTIGEN P24; NANOPARTICLE; STREPTAVIDIN;

ANTIGEN DETECTION; ARTICLE; BIOBARCODE AMPLIFICATION ASSAY; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE AMPLIFICATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INTERMETHOD COMPARISON; LABORATORY DIAGNOSIS; NANOTECHNOLOGY; PRIORITY JOURNAL; SAMPLE; SENSITIVITY AND SPECIFICITY; SEROCONVERSION; SIGNAL TRANSDUCTION;

HIV ANTIBODIES; HIV CORE PROTEIN P24; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOLOGIC TESTS; NANOPARTICLES; NUCLEIC ACID AMPLIFICATION TECHNIQUES; SENSITIVITY AND SPECIFICITY; TIME FACTORS; VIRAL LOAD;

EID: 34748820565     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e31814a554b     Document Type: Article

References (39)

1. Fiebig EW, Wright DJ, Rawal BD, et al. Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS. 2003;17:1871-1879.
2. Petersen LR, Satten GA, Dodd R, et al. Duration of time from onset of human immunodeficiency virus type 1 infectiousness to development of detectable antibody. The HIV Seroconversion Study Group. Transfusion. 1994;34:283-289.
3. Stramer SL, Caglioti S, Strong DM. NAT of the United States and Canadian blood supply. Transfusion. 2000;40:1165-1168.
4. Schupbach J, Flepp M, Pontelli D, et al. Heat-mediated immune complex dissociation and enzyme-linked immunosorbent assay signal amplification render p24 antigen detection in plasma as sensitive as HIV-1 RNA detection by polymerase chain reaction. AIDS. 1996;10:1085-1090.
5. Nishanian P, Huskins KR, Stehn S, et al. A simple method for improved assay demonstrates that HIV p24 antigen is present as immune complexes in most sera from HIV-infected individuals. J Infect Dis. 1990;162:21-28.
6. Schupbach J, Tomasik Z, Knuchel M, et al. Optimized virus disruption improves detection of HIV-1 p24 in particles and uncovers a p24 reactivity in patients with undetectable HIV-1 RNA under long-term HAART. J Med Virol. 2006;78:1003-1010.
7. Bobrow MN, Harris TD, Shaughnessy KJ, et al. Catalyzed reporter deposition, a novel method of signal amplification. Application to immunoassays. J Immunol Methods. 1989;125:279-285.
8. Schupbach J, Boni J, Tomasik Z, et al. Sensitive detection and early prognostic significance of p24 antigen in heat-denatured plasma of human immunodeficiency virus type 1-infected infants. Swiss Neonatal HIV Study Group. J Infect Dis. 1994;170:318-324.
9. Sutthent R, Gaudart N, Chokpaibulkit K, et al. p24 Antigen detection assay modified with a booster step for diagnosis and monitoring of human immunodeficiency virus type 1 infection. J Clin Microbiol. 2003;41:1016-1022.
10. Layne SP, Merges MJ, Dembo M, et al. Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virus. Virology. 1992;189:695-714.
11. Barletta JM, Edelman DC, Constantine NT. Lowering the detection limits of HIV-1 viral load using real-time immuno-PCR for HIV-1 p24 antigen. Am J Clin Pathol. 2004;122:20-27.
12. Schupbach J, Boni J, Bisset LR, et al. HIV-1 p24 antigen is a significant inverse correlate of CD4 T-cell change in patients with suppressed viremia under long-term antiretroviral therapy. J Acquir Immune Defic Syndr. 2003;33:292-299.
13. Mirkin CA, Letsinger RL, Mucic RC, et al. A DNA-based method for rationally assembling nanoparticles into macroscopic materials. Nature. 1996;382:607-609.
14. Rosi NL, Mirkin CA. Nanostructures in biodiagnostics. Chem Rev. 2005;105:1547-1562.
15. Nam JM, Thaxton CS, Mirkin CA. Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science. 2003;301:1884-1886.
16. Nam JM, Stoeva SI, Mirkin CA. Bio-bar-code-based DNA detection with PCR-like sensitivity. J Am Chem Soc. 2004;126:5932-5933.
17. Bao YP, Wei TF, Lefebvre PA, et al. Detection of protein analytes via nanoparticle-based bio bar code technology. Anal Chem. 2006;78:2055-2059.
18. Georganopoulou DG, Chang L, Nam JM, et al. Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease. Proc Natl Acad Sci USA. 2005;102:2273-2276.
19. Nam JM, Wise AR, Groves JT. Colorimetric bio-barcode amplification assay for cytokines. Anal Chem. 2005;77:6985-6988.
20. Stoeva SI, Lee JS, Smith JE, et al. Multiplexed detection of protein cancer markers with biobarcoded nanoparticle probes. J Am Chem Soc. 2006;128:8378-8379.
21. Oh BK, Nam JM, Lee SW, et al. A fluorophore-based bio-barcode amplification assay for proteins. Small. 2006;2:103-108.
22. Stoeva SI, Lee JS, Thaxton CS, et al. Multiplexed DNA detection with biobarcoded nanoparticle probes. Angew Chem Int Ed Engl. 2006;45:3303-3306.
23. Thaxton CS, Georganopoulou DG, Mirkin CA. Gold nanoparticle probes for the detection of nucleic acid targets. Clin Chim Acta. 2006;363:120-126.
24. Wehrly K, Chesebro B. p24 antigen capture assay for quantification of human immunodeficiency virus using readily available inexpensive reagents. Methods. 1997;12:288-293.
25. Simon JH, Fouchier RA, Southerling TE, et al. The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells. J Virol. 1997;71:5259-5267.
26. Bounou S, Leclerc JE, Tremblay MJ. Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo. J Virol. 2002;76:1004-1014.
27. Taton TA, Mirkin CA, Letsinger RL. Scanometric DNA array detection with nanoparticle probes. Science. 2000;289:1757-1760.
28. Storhoff JJ, Marla SS, Bao P, et al. Gold nanoparticle-based detection of genomic DNA targets on microarrays using a novel optical detection system. Biosens Bioelectron. 2004;19:875-883.
29. Summers MF, Henderson LE, Chance MR, et al. Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1. Protein Sci. 1992;1:563-574.
30. Terwilliger EF, Cohen EA, Lu YC, et al. Functional role of human immunodeficiency virus type 1 vpu. Proc Natl Acad Sci USA. 1989;86:5163-5167.
31. Vogt VM, Simon MN. Mass determination of rous sarcoma virus virions by scanning transmission electron microscopy. J Virol. 1999;73:7050-7055.
32. Yerly S, Kaiser L, Perneger TV, et al. Time of initiation of antiretroviral therapy: impact on HIV-1 viraemia. The Swiss HIV Cohort Study. AIDS. 2000;14:243-249.
33. Kolk DP, Dockter J, Linnen J, et al. Significant closure of the human immunodeficiency virus type 1 and hepatitis C virus preseroconversion detection windows with a transcription-mediated-amplification-driven assay. J Clin Microbiol. 2002;40:1761-1766.
34. Piwowar-Manning EM, Henderson TA, Brisbin L, et al. A modified ultrasensitive assay to detect quantified HIV-1 RNA of fewer than 50 copies per milliliter. Am J Clin Pathol. 2003;120:268-270.
35. Schier R, McCall A, Adams GP, et al. Isolation of picomolar affinity antic-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site. J Mol Biol. 1996;263:551-567.
36. Saviranta P, Okon R, Brinker A, et al. Evaluating sandwich immunoassays in microarray format in terms of the ambient analyte regime. Clin Chem. 2004;50:1907-1920.
37. Fauci AS. Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science. 1993;262:1011-1018.
38. Ledergerber B, Flepp M, Boni J, et al. Human immunodeficiency virus type 1 p24 concentration measured by boosted ELISA of heat-denatured plasma correlates with decline in CD4 cells, progression to AIDS, and survival: comparison with viral RNA measurement. J Infect Dis. 2000;181:1280-1288.
39. Schupbach J. Viral RNA and p24 antigen as markers of HIV disease and antiretroviral treatment success. Int Arch Allergy Immunol. 2003;132:196-209.