Non-invasive time-lapsed monitoring and quantification of engineered bone-like tissue

Annals of Biomedical Engineering

Volumn 35, Issue 10, 2007, Pages 1657-1667

  Hagenmüller, Henri ^a   Hofmann, Sandra ^a   Kohler, Thomas ^a   Merkle, Hans P ^a   Kaplan, David L ^b   Vunjak Novakovic, Gordana ^c   Müller, Ralph ^a   Meinel, Lorenz ^a  

^a ETH ZURICH   (Switzerland)

^b Tufts University   (United States)

^c Columbia University ^*  (United States)

Author keywords

Bone; Human mesenchymal stem cells; Micro computed tomography; Scaffold; Silk; Tissue engineering

Indexed keywords

BONE; COMPUTERIZED TOMOGRAPHY; IMAGING SYSTEMS; PROTEINS; SCAFFOLDS;

HUMAN MESENCHYMAL STEM CELLS; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRY;

TISSUE ENGINEERING;

ARTICLE; BONE; BONE DENSITY; BONE DEVELOPMENT; BONE PROSTHESIS; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; HUMAN; MESENCHYMAL STEM CELL; METHODOLOGY; OSTEOBLAST; PHYSIOLOGY; RADIOGRAPHY; TISSUE ENGINEERING;

BONE AND BONES; BONE DENSITY; BONE SUBSTITUTES; CELL DIFFERENTIATION; CELLS, CULTURED; HUMANS; MESENCHYMAL STEM CELLS; OSTEOBLASTS; OSTEOGENESIS; TISSUE ENGINEERING;

EID: 34548864639     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-007-9338-2     Document Type: Article

References (35)

1. Alsberg E., E. E. Hill, D. J. Mooney. Craniofacial tissue engineering. Crit. Rev. Oral Biol. Med. 12:64-75, 2001
2. Asakura A., M. Komaki, M. Rudnicki. Muscle satellite cells are multipotential stem cells that exhibit myogenic, osteogenic, and adipogenic differentiation. Differentiation 68:245-253, 2001
3. Beetz A., G. Messer, T. Oppel, D. van Beuningen, R. U. Peter, P. Kind. Induction of interleukin 6 by ionizing radiation in a human epithelial cell line: control by corticosteroids. Int. J. Radiat. Biol. 72:33-43, 1997
4. Cartmell S., K. Huynh, A. Lin, S. Nagaraja, R. Guldberg. Quantitative microcomputed tomography analysis of mineralization within three-dimensional scaffolds in vitro. J. Biomed. Mater. Res. A 69:97-104, 2004
5. Demarteau O., D. Wendt, A. Braccini, M. Jakob, D. Schafer, M. Heberer, I. Martin. Dynamic compression of cartilage constructs engineered from expanded human articular chondrocytes. Biochem. Biophys. Res. Commun. 310:580-588, 2003
6. Enomoto A., N. Suzuki, Y. Kang, K. Hirano, Y. Matsumoto, J. Zhu, A. Morita, Y. Hosoi, K. Sakai, H. Koyama. Decreased c-Myc expression and its involvement in X-ray-induced apoptotic cell death of human T-cell leukaemia cell line MOLT-4. Int. J. Radiat. Biol. 79:589-600, 2003
7. Freyria A. M., Y. Yang, H. Chajra, C. F. Rousseau, M. C. Ronziere, D. Herbage, A. J. El Haj. Optimization of dynamic culture conditions: effects on biosynthetic activities of chondrocytes grown in collagen sponges. Tissue Eng. 11:674-684, 2005
8. Hallahan D. E., E. Dunphy, J. Kuchibhotla, A. Kraft, T. Unlap, R. R. Weichselbaum. Prolonged c-jun expression in irradiated ataxia telangiectasia fibroblasts. Int. J. Radiat. Oncol. Biol. Phys. 36:355-360, 1996
9. Hildebrand T., A. Laib, R. Müller, J. Dequeker, P. Rüegsegger. Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus. J. Bone Miner. Res. 14:1167-1174, 1999
10. Hildebrand T., P. Ruegsegger. Quantification of bone microarchitecture with the structure model index. Comput. Methods Biomech. Biomed. Eng. 1:15-23, 1997
11. Hofmann S., H. Hagenmuller, A. M. Koch, R. Muller, G. Vunjak-Novakovic, D. L. Kaplan, H. P. Merkle, L. Meinel. Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds. Biomaterials 28:1152-1162, 2007
12. Hollinger J. O., S. Winn, J. Bonadio. Options for tissue engineering to address challenges of the aging skeleton. Tissue Eng. 6:341-350, 2000
13. Ishaug S. L., G. M. Crane, M. J. Miller, A. W. Yasko, M. J. Yaszemski, A. G. Mikos. Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds. J. Biomed. Mater. Res. 36:17-28, 1997
14. Ishaug-Riley S. L., G. M. Crane-Kruger, M. J. Yaszemski, A. G. Mikos. Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers. Biomaterials 19:1405-1412, 1998
15. Karageorgiou, V., M. Tomkins, R. Fajardo, L. Meinel, B. Snyder, K. Wade, J. Chen, G. Vunjak-Novakovic, D. L. Kaplan. Porous silk fibroin 3-D scaffolds for delivery of bone morphogenetic protein-2 in vitro and in vivo. J. Biomed. Mater. Res. A 78:324-334, 2006
16. Martin I., D. Wendt, M. Heberer. The role of bioreactors in tissue engineering. Trends Biotechnol. 22:80-86, 2004
17. Meinel L., R. Fajardo, S. Hofmann, R. Langer, J. Chen, B. Snyder, G. Vunjak-Novakovic, D. Kaplan. Silk implants for the healing of critical size bone defects. Bone 37:688-698, 2005
18. Meinel L., S. Hofmann, O. Betz, R. Fajardo, H. P. Merkle, R. Langer, C. H. Evans, G. Vunjak-Novakovic, D. L. Kaplan. Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: comparison of adenovirus mediated gene transfer and protein delivery of BMP-2. Biomaterials 27:4993-5002, 2006
19. Meinel L., V. Karageorgiou, R. Fajardo, B. Snyder, V. Shinde-Patil, L. Zichner, D. Kaplan, R. Langer, G. Vunjak-Novakovic. Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow. Ann. Biomed. Eng. 32:112-122, 2004
20. Meinel L., V. Karageorgiou, S. Hofmann, R. Fajardo, B. Snyder, C. Li, L. Zichner, R. Langer, G. Vunjak-Novakovic, D. L. Kaplan. Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds. J. Biomed. Mater. Res. A 71:25-34, 2004
21. Müller R., T. Hildebrand, P. Rüegsegger. Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone. Phys. Med. Biol. 39:145-164, 1994
22. Müller R., P. Rüegsegger. Micro-tomographic imaging for the nondestructive evaluation of trabecular bone architecture. Stud. Health Technol. Inform. 40:61-79, 1997
23. Nazarov R., H. J. Jin, D. L. Kaplan. Porous 3-D scaffolds from regenerated silk fibroin. Biomacromolecules 5:718-726, 2004
24. Neuhof D., A. Ruess, F. Wenz, K. J. Weber. Induction of telomerase activity by irradiation in human lymphoblasts. Radiat. Res. 155:693-697, 2001
25. Pittenger M. F., A. M. Mackay, S. C. Beck, R. K. Jaiswal, R. Douglas, J. D. Mosca, M. A. Moorman, D. W. Simonetti, S. Craig, D. R. Marshak. Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147, 1999
26. Risbud M. V., M. Sittinger. Tissue engineering: advances in in vitro cartilage generation. Trends Biotechnol. 20:351-356, 2002
27. Ritman E. L. Micro-computed tomography-current status and developments. Annu. Rev. Biomed. Eng. 6:185-208, 2004
28. Rogakou E. P., C. Boon, C. Redon, W. M. Bonner. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146:905-916, 1999
29. Rüegsegger P., B. Koller, R. Müller. A microtomographic system for the nondestructive evaluation of bone architecture. Calcif. Tissue Int. 58:24-29, 1996
30. Seifert B., G. Mihanetzis, T. Groth, W. Albrecht, K. Richau, Y. Missirlis, D. Paul, G. von Sengbusch. Polyetherimide: a new membrane-forming polymer for biomedical applications. Artif. Organs 26:189-199, 2002
31. Sikavitsas V. I., G. N. Bancroft, J. J. Lemoine, M. A. Liebschner, M. Dauner, A. G. Mikos. Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds. Ann. Biomed. Eng. 33:63-70, 2005
32. Singh H., S. H. Teoh, H. T. Low, D. W. Hutmacher. Flow modelling within a scaffold under the influence of uni-axial and bi-axial bioreactor rotation. J. Biotechnol. 119:181-196, 2005
33. Vunjak-Novakovic G., L. Meinel, G. Altman, D. Kaplan. Bioreactor cultivation of osteochondral grafts. Orthod. Craniofac. Res. 8:209-218, 2005
34. Wang Y., U. J. Kim, D. J. Blasioli, H. J. Kim, D. L. Kaplan. In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells. Biomaterials 26:7082-7094, 2005
35. Washburn N. R., M. Weir, P. Anderson, K. Potter. Bone formation in polymeric scaffolds evaluated by proton magnetic resonance microscopy and X-ray microtomography. J. Biomed. Mater. Res. A 69:738-747, 2004