Assessment of skin absorption and irritation potential of arachidonic acid and glyceryl arachidonate using in vitro diffusion cell techniques

Food and Chemical Toxicology

Volumn 45, Issue 11, 2007, Pages 2109-2117

  Eppler, A R ^a,b   Kraeling, M E K ^a   Wickett, R R ^b   Bronaugh, R L ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Alternative method; Arachidonic acid (AA); Dermal penetration; Glyceryl arachidonate (GA); Percutaneous absorption; Skin irritation

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ARACHIDONIC ACID; ARACHIDONIC ACID DERIVATIVE; COSMETIC; DODECYL SULFATE SODIUM; ESTER DERIVATIVE; GLYCEROL; GLYCEROL ARACHIDONATE; GLYCEROL DERIVATIVE; INTERLEUKIN 1ALPHA; POLYSORBATE 80; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DEVICE; DIFFUSION; EMULSION; FEMALE; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; NONHUMAN; RAT; SKIN ABSORPTION; SKIN IRRITATION; SKIN PENETRATION; SKIN WATER LOSS; TECHNIQUE;

ANIMALS; ARACHIDONIC ACID; DIFFUSION CHAMBERS, CULTURE; FEMALE; GLYCERIDES; HUMANS; INTERLEUKIN-1ALPHA; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION; SKIN IRRITANCY TESTS; TIME FACTORS;

RATTUS;

EID: 34548831916     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2007.05.004     Document Type: Article

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