Effect of JP-8 jet fuel on molecular and histological parameters related to acute skin irritation

Toxicology and Applied Pharmacology

Volumn 175, Issue 1, 2001, Pages 83-88

  Kabbur, Mahendra B ^a   Rogers, James V ^b   Gunasekar, Palur G ^c   Garrett, Carol M ^b   Geiss, Kevin T ^b   Brinkley, William W ^a   McDougal, James N ^b,c  

^a AIR FORCE RESEARCH LABORATORY   (United States)

^b SCIENCE APPLICATIONS INTERNATIONAL CORPORATION   (United States)

^c WRIGHT STATE UNIVERSITY   (United States)

Author keywords

Inducible nitric oxide synthase; Interleukin 1 ; JP 8; Skin

Indexed keywords

FUEL; INTERLEUKIN 1 DERIVATIVE; NITRIC OXIDE SYNTHASE; NITRITE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL INFILTRATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GRANULOCYTE; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SKIN IRRITATION; TIME; WESTERN BLOTTING;

EID: 0035880926     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2001.9248     Document Type: Article

References (37)

1. Identification of early biomarkers of inflammation produced by keratinocytes exposed to jet fuels Jet A, JP-8, and JP-8(100)
2. Cytokine induction as a measure of cutaneous toxicity in primary and immortalized porcine keratinocytes exposed to jet fuels, and their relationship to normal human epidermal keratinocytes
3. Regulation of inducible nitric oxide synthase mRNA levels by differentiation and cytokines in human keratinocytes
4. Peroxynitrite: Mediator of the toxic action of nitric oxide
5. Irritants - Organic solvents
6. Endogenous interleukin-1α is associated with skin irritation induced by tributyltin
7. Cytokines and irritant contact dermatitis
8. Cytokine fingerprinting: Characterization of chemical allergens
9. Epidermal cytokines in murine cutaneous irritant responses
10. Large induction of the chemotactic cytokine RANTES during cutaneous wound repair: A regulatory role for nitric oxide in keratinocyte-derived RANTES expression
11. Evaluation of the contribution of chronic skin irritation and selected compositional parameters to the tumorigenicity of petroleum middle distillates in mouse skin
12. A 90-day toxicity study of the effects of petroleum middle distillates on the skin of C3H mice
13. Different pathways in irritant contact eczma? Early differences in the epidermal elemental content and expression of cytokines after application of 2 different irritants
14. Physiologically based modeling of nonsteady state dermal absorption of halogenated methanes from an aqueous solution
15. Evaluation of skin sensitization potential of jet fuels by murine local lymph node assay
16. Acute irritation and sensitization potential of JP-8 jet fuel
17. Reactive nitrogen intermediates and antimicrobial activity - Role of nitrite
18. Immune and inflammatory processes in cutaneous tissues
19. The interleukin-1 axis and cutaneous inflammation
20. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
21. Protective role of nitric oxide-mediated inflammatory response against lipid peroxidation in ultraviolet B-irradiated skin
22. Inflammatory damage to skin by prolonged contact with 1,2-dichlorobenzene and chloropentafluorobenzene
23. Assessment of skin absorption and penetration of JP-8 jet fuel and its components
24. Interleukin-1 and cutaneous inflammation: A crucial link between innate and acquired immunity
25. Inducible nitric oxide synthase demonstrated in allergic and irritant contact dermatitis
26. Mechanisms of chemically induced skin irritation: Studies of time course, dose response, and components of inflammation in the laboratory mouse
27. Inhalation exposure to JP-8 jet fuel alters pulmonary function and substance P levels in Fischer 344 rats
28. Involvement of NO in contact hypersensitivity
29. Supplemental dietary arginine enhances wound healing in normal but not inducible nitric oxide synthase knockout mice
30. Effect of chronic low-level exposure to jet fuel on postural balance of US Air Force personnel
31. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and applications
32. Dermal application of JP-8 jet fuel induces immune suppression
33. Biology and clinical relevance of nitric oxide
34. Barrier disruption stimulates interleukin-1 alpha expression and release from a pre-formed pool in murine epidermis
35. Ultraviolet B radiation downregulates inducible nitric oxide synthase expression induced by interferon-γ or tumor necrosis factor-α in murine keratinocytes Pam 212 cells