Age-dependent differential expression of fibronectin variants in skin and airway mucosal wounds

Archives of Otolaryngology - Head and Neck Surgery

Volumn 133, Issue 9, 2007, Pages 919-924

  Li Korotky, Ha Sheng ^a,b,c   Hebda, Patricia A ^a,b,c   Lo, Chia Yee ^a   Dohar, Joseph E ^a,b,c  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; FIBRONECTIN; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FN1; TRANSCRIPTION FACTOR SRP20; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FETUS; GENETIC VARIABILITY; MOLECULAR CLONING; MOLECULAR GENETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN VARIANT; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INJURY; RNA PROCESSING; RNA TRANSCRIPTION; SKIN INJURY; WOUND HEALING;

AGE FACTORS; ALTERNATIVE SPLICING; ANIMALS; DNA, COMPLEMENTARY; FEMALE; FIBRONECTINS; PREGNANCY; PRENATAL INJURIES; PROTEIN ISOFORMS; RABBITS; RESPIRATORY MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PRECURSORS; RNA, MESSENGER; SKIN; TRANSCRIPTION, GENETIC; VARIATION (GENETICS); WEANING; WOUND HEALING;

EID: 34548721110     PISSN: 08864470     EISSN: 08864470     Source Type: Journal    
DOI: 10.1001/archotol.133.9.919     Document Type: Article

References (52)

1. Dohar JE, Stool SE. Respiratory mucosa wound healing and its management: an overview. Otolaryngol Clin North Am. 1995;28(5):897-912.
2. Dohar JE, Klein EC, Betsch JL, Hebda PA. Acquired subglottic stenosis - depth and not extent of the insult is key. Int J Pediatr Otorhinolaryngol. 1998;46(3):159-170.
3. Kadilak PR, Vanasse S, Sheridan RL. Favorable short- and long-term outcomes of prolonged translaryngeal intubation in critically ill children. J Burn Care Rehabil. 2004;25(3):262-265.
4. Lorenz RR. Adult laryngotracheal stenosis: etiology and surgical management. Curr Opin Otolaryngol Head Neck Surg. 2003;11(6):467-472.
5. Dohar JE, Klein EC, Betsch JL, Hebda PA. Fetal airway wound repair: a new frontier. Arch Otolaryngol Head Neck Surg. 1998;124(1):25-29.
6. Li-Korotky HS, Hebda PA, Kelly LA, Lo CY, Dohar JE. Identification of a premRNA splicing factor, arginine/serine-rich 3 (Sfrs3), and its co-expression with fibronectin in fetal and postnatal rabbit airway mucosal and skin wounds. Biochim Biophys Acta. 2006;1762(1):34-45.
7. Clemmensen I. Significance of plasma fibronectin. Haematologia (Budap). 1984;17(1):101-106.
8. Vaheri A. Fibronectin (cold-insoluble globulin): role in defense. Schweiz Med Wochenschr. 1980;110(40):1437-1440.
9. Clark RA, Winn HJ, Dvorak HF, Colvin RB. Fibronectin beneath reepithelializing epidermis in vivo: sources and significance. J Invest Dermatol. 1983;80:26s-30s.
10. Kornblihtt AR, Pesce CG, Alonso CR, et al. The fibronectin gene as a model for splicing and transcription studies. FASEB J. 1996;10(2):248-257.
11. Pankov R, Yamada KM. Fibronectin at a glance. J Cell Sci. 2002;115(pt 20):3861-3863.
12. Kornblihtt AR, Umezawa K, Vibe-Pedersen K, Baralle FE. Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene. EMBO J. 1985;4(7):1755-1759.
13. Schwarzbauer JE. Alternative splicing of fibronectin: three variants, three functions. Bioessays. 1991;13(10):527-533.
14. Arai H, Hirano H, Mushiake S, Nakayama M, Takada G, Sekiguchi K. Loss of EDB+ fibronectin isoform is associated with differentiation of alveolar epithelial cells in human fetal lung. Am J Pathol. 1997;151(2):403-412.
15. Gutman A, Kornblihtt AR. Identification of a third region of cell-specific alternative splicing in human fibronectin mRNA. Proc Natl Acad Sci U S A. 1987;84(20):7179-7182.
16. Couchman JR, Austria MR, Woods A. Fibronectin-cell interactions. J Invest Dermatol. 1990;94(6)(suppl):7S-14S.
17. Maniscalco WM, Watkins RH, Campbell MH. Expression of fibronectin mRNA splice variants by rabbit lung in vivo and by alveolar type II cells in vitro. Am J Physiol. 1996;271(6, pt 1):L972-L980.
18. Paolella G, Henchcliffe C, Sebastio G, Baralle FE. Sequence analysis and in vivo expression show that alternative splicing of ED-B and ED-A regions of the human fibronectin gene are independent events. Nucleic Acids Res. 1988;16(8):3545-3557.
19. Huh GS, Hynes RO. Elements regulating an alternatively spliced exon of the rat fibronectin gene. Mol Cell Biol. 1993;13(9):5301-5314.
20. Vibe-Pedersen K, Magnusson S, Baralle FE. Donor and acceptor splice signals within an exon of the human fibronectin gene: a new type of differential splicing. FEBS Lett. 1986;207(2):287-291.
21. Rairkar A, Rubino HM, Lockard RE. Revised primary structure of rabbit 18S ribosomal RNA. Nucleic Acids Res. 1988;16(7):3113.
22. Li HS, Doyle WJ, Swarts JD, Hebda PA. Suppression of epithelial ion transport transcripts during pneumococcal acute otitis media in the rat. Acta Otolaryngol. 2002;122(5):488-494.
23. Schmittgen TD, Zakrajsek BA, Mills AG, Gorn V, Singer MJ, Reed MW. Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods. Anal Biochem. 2000;285(2):194-204.
24. F-French-Constant C, Van de Water L, Dvorak HF, Hynes RO. Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat. J Cell Biol. 1989;109(2):903-914.
25. Brown LF, Dubin D, Lavigne L, Logan B, Dvorak HF, Van de Water L. Macrophages and fibroblasts express embryonic fibronectins during cutaneous wound healing. Am J Pathol. 1993;142(3):793-801.
26. Singh P, Reimer CL, Peters JH, Stepp MA, Hynes RO, Van De Water L. The spatial and temporal expression patterns of integrin alpha9beta1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing. J Invest Dermatol. 2004;123(6):1176-1181.
27. Cai X, Foster CS, Liu JJ, et al. Alternatively spliced fibronectin molecules in the wounded cornea: analysis by PCR. Invest Ophthalmol Vis Sci. 1993;34(13):3585-3592.
28. Vitale AT, Pedroza-Seres M, Arrunategui-Correa V, et al. Differential expression of alternatively spliced fibronectin in normal and wounded rat corneal stroma versus epithelium. Invest Ophthalmol Vis Sci. 1994;35(10):3664-3672.
29. Nickeleit V, Kaufman AH, Zagachin L, Dutt JE, Foster CS, Colvin RB. Healing corneas express embryonic fibronectin isoforms in the epithelium, subepithelial stroma, and endothelium. Am J Pathol. 1996;149(2):549-558.
30. Havrlikova K, Mellott M, Kaufman AH, et al. Expression of fibronectin isoforms bearing the alternatively spliced EIIIA, EIIIB, and V segments in corneal alkali burn and keratectomy wound models in the rat. Cornea. 2004;23(8):812-818.
31. Tominaga K, Higuchi K, Watanabe T, et al. Expression of gene for EIIIA- and EIIIB-fibronectin, fetal types of fibronectin, during gastric ulcer healing in rats. Dig Dis Sci. 2001;46(2):311-317.
32. George J, Wang SS, Sevcsik AM, et al. Transforming growth factor-beta initiates wound repair in rat liver through induction of the EIIIA-fibronectin splice isoform. Am J Pathol. 2000;156(1):115-124.
33. Jarnagin WR, Rockey DC, Koteliansky VE, Wang SS, Bissell DM. Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J Cell Biol. 1994;127(6, pt 2):2037-2048.
34. Ulrich MM, Janssen AM, Daemen MJ, et al. Increased expression of fibronectin isoforms after myocardial infarction in rats. J Mol Cell Cardiol. 1997;29(9):2533-2543.
35. Peters JH, Loredo GA, Chen G, et al. Plasma levels of fibronectin bearing the alternatively spliced EIIIB segment are increased after major trauma. J Lab Clin Med. 2003;141(6):401-410.
36. Barnes JL, Torres ES, Mitchell RJ, Peters JH. Expression of alternatively spliced fibronectin variants during remodeling in proliferative glomerulonephritis. Am J Pathol. 1995;147(5):1361-1371.
37. Alonso J, Gomez-Chiarri M, Ortiz A, et al. Glomerular up-regulation of EIIIA and V120 fibronectin isoforms in proliferative immune complex nephritis. Kidney Int. 1996;50(3):908-919.
38. Mathews GA, Ffrench-Constant C. Embryonic fibronectins are up-regulated following peripheral nerve injury in rats. J Neurobiol. 1995;26(2):171-188.
39. Powell FS, Doran JE. Current status of fibronectin in transfusion medicine: focus on clinical studies. Vox Sang. 1991;60(4):193-202.
40. Yoder MC. Therapeutic administration of fibronectin: current uses and potential applications. Clin Perinatol. 1991;18(2):325-341.
41. Orem C, Orem A, Calapoglu M, Baykan M, Uydu HA, Erdol C. Plasma fibronectin level and its relationships with lipids, lipoproteins and C-reactive protein in patients with dyslipidaemia during lipid-lowering therapy. Acta Cardiol. 2002;57(6):421-425.
42. Koenn ME. Fetal fibronectin. Clin Lab Sci. 2002;15(2):96-98.
43. Pagani F, Zagato L, Vergani C, Casari G, Sidoli A, Baralle FE. Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat. J Cell Biol. 1991;113(5):1223-1229.
44. Norton PA, Hynes RO. Alternative splicing of chicken fibronectin in embryos and in normal and transformed cells. Mol Cell Biol. 1987;7(12):4297-4307.
45. Barone MV, Henchcliffe C, Baralle FE, Paolella G. Cell type specific trans-acting factors are involved in alternative splicing of human fibronectin pre-mRNA. EMBO J. 1989;8(4):1079-1085.
46. Longaker MT, Whitby DJ, Ferguson MW, et al. Studies in fetal wound healing: III. Early deposition of fibronectin distinguishes fetal from adult wound healing. J Pediatr Surg. 1989;24(8):799-805.
47. Whitby DJ, Ferguson MW. The extracellular matrix of lip wounds in fetal, neonatal and adult mice. Development. 1991;112(2):651-668.
48. van der Straaten HM, Canninga-van Dijk MR, Verdonck LF, et al. Extradomain-A fibronectin: a new marker of fibrosis in cutaneous graft-versus-host disease. J Invest Dermatol. 2004;123(6):1057-1062.
49. Kilian O, Dahse R, Alt V, et al. Expression of EDA+ and EDB+ fibronectin splice variants in bone. Bone. 2004;35(6):1334-1345.
50. Astrof S, Crowley D, George EL, et al. Direct test of potential roles of EIIIA and EIIIB alternatively spliced segments of fibronectin in physiological and tumor angiogenesis. Mol Cell Biol. 2004;24(19):8662-8670.
51. Muro AF, Chauhan AK, Gajovic S, et al. Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan. J Cell Biol. 2003;162(1):149-160.
52. Tan MH, Sun Z, Opitz SL, Schmidt TE, Peters JH, George EL. Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis. Blood. 2004;104(1):11-18.