Suppression of epithelial ion transport transcripts during pneumococcal acute otitis media in the rat

Acta Oto-Laryngologica

Volumn 122, Issue 5, 2002, Pages 488-494

  Li, H S ^a,b   Doyle, W J ^a,b   Swarts, J D ^a,b   Hebda, P A ^a,b  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Acute bacterial infection; Gene expression; Middle ear mucosa; Real time polymerase chain reaction; Sodium channel; Sodium pump; Sodium hydrogen exchanger

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA 1; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) BETA; CARRIER PROTEIN; ION; SODIUM CHANNEL; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 2; UNCLASSIFIED DRUG; WATER; SODIUM;

ACIDIFICATION; ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BACTERIAL INFECTION; BASOLATERAL MEMBRANE; CONTROLLED STUDY; DNA MICROARRAY; ELECTROCHEMISTRY; ENZYME SUBUNIT; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETIC SCREENING; GENETIC VARIABILITY; INFLAMMATION; ION TRANSPORT; MALE; MIDDLE EAR; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOSIS; OTITIS MEDIA; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SODIUM CHANNEL BETA 2 SUBUNIT; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE; TRANSCRIPTION REGULATION; ANIMAL; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ACUTE DISEASE; ANIMAL; GENE EXPRESSION; ION TRANSPORT; MALE; OTITIS MEDIA; PNEUMOCOCCAL INFECTIONS; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SODIUM CHANNELS; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS; TRANSCRIPTION, GENETIC; ANIMALS;

EID: 0035994957     PISSN: 00016489     EISSN: None     Source Type: Journal    
DOI: 10.1080/00016480260092273     Document Type: Article

References (21)

1. Increasing importance of viruses in acute otitis media
2. Clinical course, complications and sequelae of acute otitis media
3. The burden of otitis media
4. Upregulation of messenger RNA for inflammatory cytokines in middle ear mucosa in a rat model of acute otitis media
5. Expression of cytokine genes during pneumococcal and nontypeable Haemophilus influenzae acute otitis media in the rat
6. Gene arrays: Acute otitis media in the rat model; AH-HA! There's the forest!
7. Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: Comparison of endpoint and real-time methods
8. Ion transports in the middle ear epithelium
9. + absorption in middle ear epithelium
10. Isozymes of the Na-K-ATPase: Heterogeneity in structure, diversity in function
11. Resurgence of sodium channel research
12. Scn2b, a voltage-gated sodium channel beta2 gene on mouse chromosome 9
13. Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif
14. Na(+)/H(+) exchangers: Linking osmotic dysequilibrium to modified cell function
15. IFN-gamma downregulates expression of Na(+)/H(+) exchangers NHE2 and NHE3 in rat intestine and human Caco-2/bbe cells
16. + conductive transport in epithelia by pH
17. CFTR modulates programmed cell death by decreasing intracellular pH in Chinese hamster lung fibroblasts
18. Epithelial sodium transport: Basic autoregulatory mechanisms
19. Glial cells production of inflammatory mediators induced by Streptococcus pneumoniae: Inhibition by pentoxifylline, low-molecular-weight heparin and dexamethasone
20. Na(+)-K(+)-ATPase expression in alveolar epithelial cells: Upregulation of active ion transport by KGF