Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells

International Journal of Cancer

Volumn 121, Issue 8, 2007, Pages 1670-1679

  Ko, Ching Huai ^a   Shen, Shing Chuan ^b,c   Yang, Liang Yo ^a   Lin, Cheng Wei ^a   Chen, Yen Chou ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Apoptosis inducing factor; Cytochrome c; Gossypol; Mitochondria; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ALLOPURINOL; APOPTOSIS INDUCING FACTOR; CATALASE; CYTOCHROME C; DIPHENYLIODONIUM SALT; DNA; ETHIDIUM BROMIDE; GOSSYPOL; GOSSYPOL ACETIC ACID; MELATONIN; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; TEMPOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CHROMOSOME CONDENSATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-ASSOCIATED DEATH PROTEIN; BCL-X PROTEIN; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; COLLAGEN TYPE XI; COLORECTAL NEOPLASMS; CYTOCHROMES C; ENZYME ACTIVATION; ETHIDIUM; FLOW CYTOMETRY; GOSSYPOL; HUMANS; MICE; MICE, NUDE; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 34548680503     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22910     Document Type: Article

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