Stable insertion of Alzheimer Aβ peptide into the ER membrane strongly correlates with its length

FEBS Letters

Volumn 581, Issue 20, 2007, Pages 3809-3813

  Lundin, Carolina ^a   Johansson, Sofia ^a   Johnson, Arthur E ^c,d   Näslund, Jan ^b   von Heijne, Gunnar ^a   Nilsson, IngMarie ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c TEXAS A AND M UNIVERSITY SYSTEM   (United States)

^d TEXAS A AND M UNIVERSITY   (United States)

Author keywords

A peptide; Amyloid protein precursor; Membrane insertion; Translocon mediated

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; BETA SECRETASE; GAMMA SECRETASE; MEMBRANE PROTEIN; POLYPEPTIDE; TRANSLOCON; AMYLOID PRECURSOR PROTEIN; PEPTIDE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; ENDOPLASMIC RETICULUM; GENE INSERTION; HYDROPHOBICITY; MICROSOME MEMBRANE; NONHUMAN; PRIORITY JOURNAL; BIOLOGICAL MODEL; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROSOME; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ENDOPLASMIC RETICULUM; MEMBRANE PROTEINS; MICROSOMES; MODELS, BIOLOGICAL; MUTAGENESIS, INSERTIONAL; PEPTIDES; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY;

EID: 34548654198     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.07.003     Document Type: Article

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