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Volumn 76, Issue 2, 2007, Pages 150-158

The human fatty acid synthase: A new therapeutic target for coxsackievirus B3-induced diseases?

Author keywords

c75; Cerulenin; Coxsackievirus; Fatty acid synthase (FAS); TOFA

Indexed keywords

5 (TETRADECYOXY) 2 FUROIC ACID; C75 PROTEIN; CERULENIN; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 34548610648     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2007.06.011     Document Type: Article
Times cited : (21)

References (58)
  • 1
    • 33744990410 scopus 로고    scopus 로고
    • Current status of anti-picornavirus therapies
    • Barnard D.L. Current status of anti-picornavirus therapies. Curr. Pharm. Des. 12 (2006) 1379-1390
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 1379-1390
    • Barnard, D.L.1
  • 2
    • 0027500350 scopus 로고
    • Coupled translation and replication of poliovirus RNA in vitro: synthesis of functional 3D polymerase and infectious virus
    • Barton D.J., and Flanegan J.B. Coupled translation and replication of poliovirus RNA in vitro: synthesis of functional 3D polymerase and infectious virus. J. Virol. 67 (1993) 822-831
    • (1993) J. Virol. , vol.67 , pp. 822-831
    • Barton, D.J.1    Flanegan, J.B.2
  • 3
    • 0030820126 scopus 로고    scopus 로고
    • Synchronous replication of poliovirus RNA: initiation of negative-strand RNA synthesis requires the guanidine-inhibited activity of protein 2C
    • Barton D.J., and Flanegan J.B. Synchronous replication of poliovirus RNA: initiation of negative-strand RNA synthesis requires the guanidine-inhibited activity of protein 2C. J. Virol. 71 (1997) 8482-8489
    • (1997) J. Virol. , vol.71 , pp. 8482-8489
    • Barton, D.J.1    Flanegan, J.B.2
  • 4
    • 0029155434 scopus 로고
    • Complete replication of poliovirus in vitro: preinitiation RNA replication complexes require soluble cellular factors for the synthesis of VPg-linked RNA
    • Barton D.J., Black E.P., and Flanegan J.B. Complete replication of poliovirus in vitro: preinitiation RNA replication complexes require soluble cellular factors for the synthesis of VPg-linked RNA. J. Virol. 69 (1995) 5516-5527
    • (1995) J. Virol. , vol.69 , pp. 5516-5527
    • Barton, D.J.1    Black, E.P.2    Flanegan, J.B.3
  • 6
    • 0022600645 scopus 로고
    • Detection of coxsackie-B-virus-specific RNA sequences in myocardial biopsy samples from patients with myocarditis and dilated cardiomyopathy
    • Bowles N.E., Richardson P.J., Olsen E.G., and Archard L.C. Detection of coxsackie-B-virus-specific RNA sequences in myocardial biopsy samples from patients with myocarditis and dilated cardiomyopathy. Lancet 1 (1986) 1120-1123
    • (1986) Lancet , vol.1 , pp. 1120-1123
    • Bowles, N.E.1    Richardson, P.J.2    Olsen, E.G.3    Archard, L.C.4
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0024352246 scopus 로고
    • Inhibition of bacterially expressed HIV protease activity determined by an in vitro cleavage assay with MuLV Pr65gag
    • Bu M., Oroszlan S., and Luftig R.B. Inhibition of bacterially expressed HIV protease activity determined by an in vitro cleavage assay with MuLV Pr65gag. AIDS Res. Hum. Retroviruses 5 (1989) 259-268
    • (1989) AIDS Res. Hum. Retroviruses , vol.5 , pp. 259-268
    • Bu, M.1    Oroszlan, S.2    Luftig, R.B.3
  • 9
    • 0031887006 scopus 로고    scopus 로고
    • Analysis of changes in acute-phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two-dimensional gel electrophoresis
    • Doherty N.S., Littman B.H., Reilly K., Swindell A.C., Buss J.M., and Anderson N.L. Analysis of changes in acute-phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two-dimensional gel electrophoresis. Electrophoresis 19 (1998) 355-363
    • (1998) Electrophoresis , vol.19 , pp. 355-363
    • Doherty, N.S.1    Littman, B.H.2    Reilly, K.3    Swindell, A.C.4    Buss, J.M.5    Anderson, N.L.6
  • 10
    • 0036100578 scopus 로고    scopus 로고
    • Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
    • Egger D., Wölk B., Gosert R., Bianchi L., Blum H.E., Moradpour D., and Bienz K. Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J. Virol. 76 (2002) 5974-5984
    • (2002) J. Virol. , vol.76 , pp. 5974-5984
    • Egger, D.1    Wölk, B.2    Gosert, R.3    Bianchi, L.4    Blum, H.E.5    Moradpour, D.6    Bienz, K.7
  • 11
    • 0142092456 scopus 로고    scopus 로고
    • Membrane requirements for uridylylation of the poliovirus VPg protein and viral RNA synthesis in vitro
    • Fogg M.H., Teterina N.L., and Ehrenfeld E. Membrane requirements for uridylylation of the poliovirus VPg protein and viral RNA synthesis in vitro. J. Virol. 77 (2003) 11408-11416
    • (2003) J. Virol. , vol.77 , pp. 11408-11416
    • Fogg, M.H.1    Teterina, N.L.2    Ehrenfeld, E.3
  • 12
    • 0021212082 scopus 로고
    • Reverse radioimmunoassays of IgM and IgG antibodies to coxsackie B viruses in patients with acute myopericarditis
    • Frisk G., Torfason E.G., and Diderholm H. Reverse radioimmunoassays of IgM and IgG antibodies to coxsackie B viruses in patients with acute myopericarditis. J. Med. Virol. 14 (1984) 191-200
    • (1984) J. Med. Virol. , vol.14 , pp. 191-200
    • Frisk, G.1    Torfason, E.G.2    Diderholm, H.3
  • 14
    • 0031830709 scopus 로고    scopus 로고
    • Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance
    • Gebhard J.R., Perry C.M., Harkins S., Lane T., Mena I., Asensio V.C., Campbell I.L., and Whitton J.L. Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance. Am. J. Pathol. 153 (1998) 417-428
    • (1998) Am. J. Pathol. , vol.153 , pp. 417-428
    • Gebhard, J.R.1    Perry, C.M.2    Harkins, S.3    Lane, T.4    Mena, I.5    Asensio, V.C.6    Campbell, I.L.7    Whitton, J.L.8
  • 15
    • 0022627231 scopus 로고
    • Idiopathic cardiomyopathy in the United States 1970-1982
    • Gillum R.F. Idiopathic cardiomyopathy in the United States 1970-1982. Am. Heart J. 111 (1986) 752-755
    • (1986) Am. Heart J. , vol.111 , pp. 752-755
    • Gillum, R.F.1
  • 16
    • 0037563355 scopus 로고    scopus 로고
    • Very alkaline immobilized pH gradients for two-dimensional electrophoresis of ribosomal and nuclear proteins
    • Görg A., Obermaier C., Boguth G., Csordas A., Diaz J.J., and Madjar J.J. Very alkaline immobilized pH gradients for two-dimensional electrophoresis of ribosomal and nuclear proteins. Electrophoresis 18 (1997) 328-337
    • (1997) Electrophoresis , vol.18 , pp. 328-337
    • Görg, A.1    Obermaier, C.2    Boguth, G.3    Csordas, A.4    Diaz, J.J.5    Madjar, J.J.6
  • 17
    • 0025328822 scopus 로고
    • Phospholipid biosynthesis and poliovirus genome replication, two coupled phenomena
    • Guinea R., and Carrasco L. Phospholipid biosynthesis and poliovirus genome replication, two coupled phenomena. EMBO J. 9 (1990) 2011-2016
    • (1990) EMBO J. , vol.9 , pp. 2011-2016
    • Guinea, R.1    Carrasco, L.2
  • 18
    • 0021715781 scopus 로고
    • Inhibition of fatty acid synthesis in isolated adipocytes by 5-(tetradecyloxy)-2-furoic acid
    • Halvorson D.L., and McCune S.A. Inhibition of fatty acid synthesis in isolated adipocytes by 5-(tetradecyloxy)-2-furoic acid. Lipids 19 (1984) 851-856
    • (1984) Lipids , vol.19 , pp. 851-856
    • Halvorson, D.L.1    McCune, S.A.2
  • 19
    • 0036733979 scopus 로고    scopus 로고
    • Key role of mitochondria in cerulenin-mediated apoptosis
    • Heiligtag S.J., Bredehorst R., and David K.A. Key role of mitochondria in cerulenin-mediated apoptosis. Cell Death Differ. 9 (2002) 1017-1025
    • (2002) Cell Death Differ. , vol.9 , pp. 1017-1025
    • Heiligtag, S.J.1    Bredehorst, R.2    David, K.A.3
  • 20
    • 0028818233 scopus 로고
    • The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis
    • Henke A., Huber S., Stelzner A., and Whitton J.L. The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis. J. Virol. 69 (1995) 6720-6728
    • (1995) J. Virol. , vol.69 , pp. 6720-6728
    • Henke, A.1    Huber, S.2    Stelzner, A.3    Whitton, J.L.4
  • 21
    • 0033993955 scopus 로고    scopus 로고
    • Apoptosis in coxsackievirus B3-caused diseases: interaction between the capsid protein VP2 and the proapoptotic protein siva
    • Henke A., Launhardt H., Klement K., Stelzner A., Zell R., and Munder T. Apoptosis in coxsackievirus B3-caused diseases: interaction between the capsid protein VP2 and the proapoptotic protein siva. J. Virol. 74 (2000) 4284-4290
    • (2000) J. Virol. , vol.74 , pp. 4284-4290
    • Henke, A.1    Launhardt, H.2    Klement, K.3    Stelzner, A.4    Zell, R.5    Munder, T.6
  • 22
    • 0035840791 scopus 로고    scopus 로고
    • The apoptotic capability of coxsackievirus B3 is influenced by the efficient interaction between the capsid protein VP2 and the proapoptotic host protein Siva
    • Henke A., Nestler M., Strunze S., Saluz H.P., Hortschansky P., Menzel B., Martin U., Zell R., Stelzner A., and Munder T. The apoptotic capability of coxsackievirus B3 is influenced by the efficient interaction between the capsid protein VP2 and the proapoptotic host protein Siva. Virology 289 (2001) 15-22
    • (2001) Virology , vol.289 , pp. 15-22
    • Henke, A.1    Nestler, M.2    Strunze, S.3    Saluz, H.P.4    Hortschansky, P.5    Menzel, B.6    Martin, U.7    Zell, R.8    Stelzner, A.9    Munder, T.10
  • 23
    • 0029925841 scopus 로고    scopus 로고
    • Modulation of cytokine expression by CD4+ T cells during coxsackievirus B3 infections of BALB/c mice initiated by cells expressing the gamma delta + T-cell receptor
    • Huber S.A., Mortensen A., and Moulton G. Modulation of cytokine expression by CD4+ T cells during coxsackievirus B3 infections of BALB/c mice initiated by cells expressing the gamma delta + T-cell receptor. J. Virol. 70 (1996) 3039-3044
    • (1996) J. Virol. , vol.70 , pp. 3039-3044
    • Huber, S.A.1    Mortensen, A.2    Moulton, G.3
  • 24
    • 0033039491 scopus 로고    scopus 로고
    • gamma delta+ T cells regulate major histocompatibility complex class II(IA and IE)-dependent susceptibility to coxsackievirus B3-induced autoimmune myocarditis
    • Huber S.A., Stone J.E., Wagner D.H., Kupperman J., Pfeiffer L., David C., O'Brien R.L., Davis G.S., and Newell M.K. gamma delta+ T cells regulate major histocompatibility complex class II(IA and IE)-dependent susceptibility to coxsackievirus B3-induced autoimmune myocarditis. J. Virol. 73 (1999) 5630-5636
    • (1999) J. Virol. , vol.73 , pp. 5630-5636
    • Huber, S.A.1    Stone, J.E.2    Wagner, D.H.3    Kupperman, J.4    Pfeiffer, L.5    David, C.6    O'Brien, R.L.7    Davis, G.S.8    Newell, M.K.9
  • 25
    • 0029843593 scopus 로고    scopus 로고
    • A mutation in the puff region of VP2 attenuates the myocarditic phenotype of an infectious cDNA of the Woodruff variant of coxsackievirus B3
    • Knowlton K.U., Jeon E.S., Berkley N., Wessely R., and Huber S. A mutation in the puff region of VP2 attenuates the myocarditic phenotype of an infectious cDNA of the Woodruff variant of coxsackievirus B3. J. Virol. 70 (1996) 7811-7818
    • (1996) J. Virol. , vol.70 , pp. 7811-7818
    • Knowlton, K.U.1    Jeon, E.S.2    Berkley, N.3    Wessely, R.4    Huber, S.5
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 29
    • 0033508486 scopus 로고    scopus 로고
    • Coxsackievirus B3-induced myocarditis in MHC class II-deficient mice
    • Leipner C., Borchers M., Merkle I., and Stelzner A. Coxsackievirus B3-induced myocarditis in MHC class II-deficient mice. J. Hum. Virol. 2 (1999) 102-114
    • (1999) J. Hum. Virol. , vol.2 , pp. 102-114
    • Leipner, C.1    Borchers, M.2    Merkle, I.3    Stelzner, A.4
  • 30
    • 1842431670 scopus 로고    scopus 로고
    • Fatty acid synthase expression is induced by the Epstein-Barr virus immediate-early protein BRLF1 and is required for lytic viral gene expression
    • Li Y., Webster-Cyriaque J., Tomlinson C.C., Yohe M., and Kenney S. Fatty acid synthase expression is induced by the Epstein-Barr virus immediate-early protein BRLF1 and is required for lytic viral gene expression. J. Virol. 78 (2004) 4197-4206
    • (2004) J. Virol. , vol.78 , pp. 4197-4206
    • Li, Y.1    Webster-Cyriaque, J.2    Tomlinson, C.C.3    Yohe, M.4    Kenney, S.5
  • 34
    • 0033525885 scopus 로고    scopus 로고
    • Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase
    • Moche M., Schneider G., Edwards P., Dehesh K., and Lindqvist Y. Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase. J. Biol. Chem. 274 (1999) 6031-6034
    • (1999) J. Biol. Chem. , vol.274 , pp. 6031-6034
    • Moche, M.1    Schneider, G.2    Edwards, P.3    Dehesh, K.4    Lindqvist, Y.5
  • 35
    • 0027323262 scopus 로고
    • Effects of temperature and lipophilic agents on poliovirus formation and RNA synthesis in a cell-free system
    • Molla A., Paul A.V., and Wimmer E. Effects of temperature and lipophilic agents on poliovirus formation and RNA synthesis in a cell-free system. J. Virol. 67 (1993) 5932-5938
    • (1993) J. Virol. , vol.67 , pp. 5932-5938
    • Molla, A.1    Paul, A.V.2    Wimmer, E.3
  • 38
    • 0342614498 scopus 로고
    • Processing of the structural proteins of human immunodeficiency virus type 1 in the presence of monensin and cerulenin
    • Pal R., Gallo R.C., and Sarngadharan M.G. Processing of the structural proteins of human immunodeficiency virus type 1 in the presence of monensin and cerulenin. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 9283-9286
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 9283-9286
    • Pal, R.1    Gallo, R.C.2    Sarngadharan, M.G.3
  • 39
    • 0037223676 scopus 로고    scopus 로고
    • Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus
    • Paul A.V., Peters J., Mugavero J., Yin J., van Boom J.H., and Wimmer E. Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus. J. Virol. 77 (2003) 891-904
    • (2003) J. Virol. , vol.77 , pp. 891-904
    • Paul, A.V.1    Peters, J.2    Mugavero, J.3    Yin, J.4    van Boom, J.H.5    Wimmer, E.6
  • 40
    • 0032444156 scopus 로고    scopus 로고
    • Inhibition of Mayaro virus replication by cerulenin in Aedes albopictus cells
    • Pereira H.S., and Rebello M.A. Inhibition of Mayaro virus replication by cerulenin in Aedes albopictus cells. Acta Virol. 42 (1998) 383-388
    • (1998) Acta Virol. , vol.42 , pp. 383-388
    • Pereira, H.S.1    Rebello, M.A.2
  • 41
    • 0034650757 scopus 로고    scopus 로고
    • Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts
    • Pizer E.S., Thupari J., Han W.F., Pinn M.L., Chrest F.J., Frehywot G.L., Townsend C.A., and Kuhajda F.P. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. Cancer Res. 60 (2000) 213-218
    • (2000) Cancer Res. , vol.60 , pp. 213-218
    • Pizer, E.S.1    Thupari, J.2    Han, W.F.3    Pinn, M.L.4    Chrest, F.J.5    Frehywot, G.L.6    Townsend, C.A.7    Kuhajda, F.P.8
  • 42
    • 0030998441 scopus 로고    scopus 로고
    • CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein
    • Prasad K.V., Ao Z., Yoon Y., Wu M.X., Rizk M., Jacquot S., and Schlossman S.F. CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 6346-6351
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 6346-6351
    • Prasad, K.V.1    Ao, Z.2    Yoon, Y.3    Wu, M.X.4    Rizk, M.5    Jacquot, S.6    Schlossman, S.F.7
  • 43
    • 0028603364 scopus 로고
    • Sample application by in-gel rehydration improves the resolution of two-dimensional electrophoresis with immobilized pH gradients in the first dimension
    • Rabilloud T., Valette C., and Lawrence J.J. Sample application by in-gel rehydration improves the resolution of two-dimensional electrophoresis with immobilized pH gradients in the first dimension. Electrophoresis 15 (1994) 1552-1558
    • (1994) Electrophoresis , vol.15 , pp. 1552-1558
    • Rabilloud, T.1    Valette, C.2    Lawrence, J.J.3
  • 45
    • 33745158157 scopus 로고
    • A simple method of estimating fifty per cent endpoints
    • Reed L.J., and Muench H. A simple method of estimating fifty per cent endpoints. Am. J. Hyg. 27 (1938) 493-497
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 46
    • 21744439458 scopus 로고    scopus 로고
    • Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates
    • Rendina A.R., and Cheng D. Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. Biochem. J. 388 (2005) 895-903
    • (2005) Biochem. J. , vol.388 , pp. 895-903
    • Rendina, A.R.1    Cheng, D.2
  • 47
    • 0022257703 scopus 로고
    • Coxsackievirus myocarditis-with special reference to acute and chronic effects
    • Reyes M.P., and Lerner A.M. Coxsackievirus myocarditis-with special reference to acute and chronic effects. Prog. Cardiovasc. Dis. 27 (1985) 373-394
    • (1985) Prog. Cardiovasc. Dis. , vol.27 , pp. 373-394
    • Reyes, M.P.1    Lerner, A.M.2
  • 50
    • 0033995576 scopus 로고    scopus 로고
    • Mutations in the 2C region of poliovirus responsible for altered sensitivity to benzimidazole derivatives
    • Shimizu H., Agoh M., Agoh Y., Yoshida H., Yoshii K., Yoneyama T., Hagiwara A., and Miyamura T. Mutations in the 2C region of poliovirus responsible for altered sensitivity to benzimidazole derivatives. J. Virol. 74 (2000) 4146-4154
    • (2000) J. Virol. , vol.74 , pp. 4146-4154
    • Shimizu, H.1    Agoh, M.2    Agoh, Y.3    Yoshida, H.4    Yoshii, K.5    Yoneyama, T.6    Hagiwara, A.7    Miyamura, T.8
  • 53
    • 0021443382 scopus 로고
    • Cerulenin resistance in a cerulenin-producing fungus. II. Characterization of fatty acid synthetase from Cephalosporium caerulens
    • Tomoda H., Kawaguchi A., Omura S., and Okuda S. Cerulenin resistance in a cerulenin-producing fungus. II. Characterization of fatty acid synthetase from Cephalosporium caerulens. J. Biochem. (Tokyo) 95 (1984) 1705-1712
    • (1984) J. Biochem. (Tokyo) , vol.95 , pp. 1705-1712
    • Tomoda, H.1    Kawaguchi, A.2    Omura, S.3    Okuda, S.4
  • 54
    • 0034766782 scopus 로고    scopus 로고
    • Rapid detection of enterovirus RNA in cerebrospinal fluid specimens with a novel single-tube real-time reverse transcription-PCR assay
    • Verstrepen W.A., Kuhn S., Kockx M.M., Van De Vyvere M.E., and Mertens A.H. Rapid detection of enterovirus RNA in cerebrospinal fluid specimens with a novel single-tube real-time reverse transcription-PCR assay. J. Clin. Microbiol. 39 (2001) 4093-4096
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 4093-4096
    • Verstrepen, W.A.1    Kuhn, S.2    Kockx, M.M.3    Van De Vyvere, M.E.4    Mertens, A.H.5
  • 55
    • 0024315871 scopus 로고
    • Fatty acid synthase, a proficient multifunctional enzyme
    • Wakil S.J. Fatty acid synthase, a proficient multifunctional enzyme. Biochemistry 28 (1989) 4523-4530
    • (1989) Biochemistry , vol.28 , pp. 4523-4530
    • Wakil, S.J.1
  • 56
    • 0032483055 scopus 로고    scopus 로고
    • Low-level expression of a mutant coxsackieviral cDNA induces a myocytopathic effect in culture: an approach to the study of enteroviral persistence in cardiac myocytes
    • Wessely R., Henke A., Zell R., Kandolf R., and Knowlton K.U. Low-level expression of a mutant coxsackieviral cDNA induces a myocytopathic effect in culture: an approach to the study of enteroviral persistence in cardiac myocytes. Circulation 98 (1998) 450-457
    • (1998) Circulation , vol.98 , pp. 450-457
    • Wessely, R.1    Henke, A.2    Zell, R.3    Kandolf, R.4    Knowlton, K.U.5
  • 57
    • 0032189260 scopus 로고    scopus 로고
    • Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy
    • Wessely R., Klingel K., Santana L.F., Dalton N., Hongo M., Jonathan Lederer W., Kandolf R., and Knowlton K.U. Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy. J. Clin. Invest. 102 (1998) 1444-1453
    • (1998) J. Clin. Invest. , vol.102 , pp. 1444-1453
    • Wessely, R.1    Klingel, K.2    Santana, L.F.3    Dalton, N.4    Hongo, M.5    Jonathan Lederer, W.6    Kandolf, R.7    Knowlton, K.U.8
  • 58
    • 0019201765 scopus 로고
    • Viral myocarditis. A review
    • Woodruff J.F. Viral myocarditis. A review. Am. J. Pathol. 101 (1980) 425-484
    • (1980) Am. J. Pathol. , vol.101 , pp. 425-484
    • Woodruff, J.F.1


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