Influence of concurrent exercise or nutrition countermeasures on thigh and calf muscle size and function during 60 days of bed rest in women

Acta Physiologica

Volumn 191, Issue 2, 2007, Pages 147-159

  Trappe, T A ^a   Burd, N A ^a   Louis, E S ^a   Lee, G A ^a   Trappe, S W ^a  

^a BALL STATE UNIVERSITY   (United States)

Author keywords

Concurrent exercise; Leucine; Microgravity; Muscle; Weightlessness; WISE 2005

Indexed keywords

LEUCINE;

ADULT; AEROBIC EXERCISE; ARTICLE; BED REST; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MUSCLE BIOPSY; MUSCLE FUNCTION; MUSCLE MASS; MUSCLE STRENGTH; MUSCLE WEAKNESS; NUTRITIONAL ASSESSMENT; PRIORITY JOURNAL; SKELETAL MUSCLE;

ADULT; ANALYSIS OF VARIANCE; BED REST; DIETARY PROTEINS; ERGOMETRY; EXERCISE THERAPY; FEMALE; HEAD-DOWN TILT; HUMANS; ISOMETRIC CONTRACTION; LEG; LEUCINE; MUSCLE, SKELETAL; MUSCULAR ATROPHY; NUTRITION PHYSIOLOGY; SPACE FLIGHT; THIGH; TIME FACTORS; WEIGHTLESSNESS SIMULATION;

EID: 34548594086     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2007.01728.x     Document Type: Article

References (69)

1. Alkner, B.A. Tesch, P.A. 2004a. Efficacy of a gravity-independent resistance exercise device as a countermeasure to muscle atrophy during 29-day bed rest. Acta Physiol Scand 181, 345 357.
2. Alkner, B.A. Tesch, P.A. 2004b. Knee extensor and plantar flexor muscle size and function following 90 days of bed rest with or without resistance exercise. Eur J Appl Physiol 93, 294 305.
3. Bell, G.J., Syrotuik, D., Martin, T.P., Burnham, R. Quinney, H.A. 2000. Effect of concurrent strength and endurance training on skeletal muscle properties and hormone concentrations in humans. Eur J Appl Physiol 81, 418 427.
4. Berg, H.E. Tesch, P.A. 1994. A gravity-independent ergometer to be used for resistance training in space. Aviat Space Environ Med, 65, 752 756.
5. Berg, H.E., Tedner, B. Tesch, P.A. 1993. Changes in lower limb muscle cross-sectional area and tissue fluid volume after transition from standing to supine. Acta Physiol Scand 148, 379 385.
6. Biolo, G., Tipton, K.D., Klein, S. Wolfe, R.R. 1997. An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol 273, E122 E129.
7. Biolo, G., Ciocchi, B., Lebenstedt, M. et al. 2004. Short-term bed rest impairs amino acid-induced protein anabolism in humans. J Physiol 558, 381 388.
8. Bohe, J., Low, J.F., Wolfe, R.R. Rennie, M.J. 2001. Latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids. J Physiol 532, 575 579.
9. Booth, F.W. Baldwin, K.M. 1996. Muscle plasticity: energy demand and supply process. In : M.J. Fregly C.M. Blatteis (eds) Handbook of Physiology, Section 4: Environmental Physiology, pp. 1075 1123. Oxford University Press, New York.
10. Buse, M.G. Reid, S.S. 1975. Leucine. A possible regulator of protein turnover in muscle. J Clin Invest 56, 1250 1261.
11. Cao, P., Kimura, S., Macias, B.R., Ueno, T., Watenpaugh, D.E. Hargens, A.R. 2005. Exercise within lower body negative pressure partially counteracts lumbar spine deconditioning associated with 28-day bed rest. J Appl Physiol 99, 39 44.
12. Carroll, C.C., Fluckey, J.D., Williams, R.H., Sullivan, D.H. Trappe, T.A. 2005. Human soleus and vastus lateralis muscle protein metabolism with an amino acid infusion. Am J Physiol Endocrinol Metab 288, E479 E485.
13. Combaret, L., Dardevet, D., Rieu, I. et al. 2005. A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle. J Physiol 569, 489 499.
14. Convertino, V.A. 1996. Exercise and adaptation to microgravity environments. In : M.J. Fregly C.M. Blatteis (eds) Handbook of Physiology, Section 4: Environmental Physiology, pp. 815 843. Oxford University Press, New York.
15. Duchateau, J. Enoka, R.M. 2002. Neural adaptations with chronic activity patterns in able-bodied humans. Am J Phys Med Rehabil, 81, S17 S27.
16. Dudley, G.A. Djamil, R. 1985. Incompatibility of endurance- and strength-training modes of exercise. J Appl Physiol, 59, 1446 1451.
17. Edgerton, V.R., Bodine-Fowler, S.C., Roy, R.R., Ishihara, A. Hodgson, J.A. 1996. Neuromuscular adaptation. In : L.B. Rowell J.T. Sheperd (eds) Handbook of Physiology, Section 12: Exercise: Regulation and Integration of Multiple Systems, pp. 54 88. Oxford University Press, New York.
18. Fortney, S.M., Schneider, V.S. Greenleaf, J.E. 1996. The physiology of bed rest. In : M.J. Fregly C.M. Blatteis (eds) Handbook of Physiology, Section 4: Environmental Physiology, pp. 889 939. Oxford University Press, New York.
19. Frexes-Steed, M., Lacy, D.B., Collins, J. Abumrad, N.N. 1992. Role of leucine and other amino acids in regulating protein metabolism in vivo. Am J Physiol 262, E925 935.
20. Gabriel, D.A., Kamen, G. Frost, G. 2006. Neural adaptations to resistive exercise: mechanisms and recommendations for training practices. Sports Med 36, 133 149.
21. Hargens, A.R., Groppo, E.R., Lee, S.M. et al. 2002. The gravity of LBNP exercise: preliminary lessons learned from identical twins in bed for 30 days. J Gravit Physiol 9, P59 62.
22. Harm, D.L., Jennings, R.T., Meck, J.V. et al. 2001. Invited review: gender issues related to spaceflight: a NASA perspective. J Appl Physiol 91, 2374 2383.
23. Hickson, R.C. 1980. Interference of strength development by simultaneously training for strength and endurance. Eur J Appl Physiol 45, 255 263.
24. Hunter, G., Demment, R. Miller, D. 1987. Development of strength and maximum oxygen uptake during simultaneous training for strength and endurance. J Sports Med Phys Fitness 27, 269 275.
25. Jones, N. 2005. Space physiology: lie back and think of science. Nature 435, 730 731.
26. Katsanos, C.S., Kobayashi, H., Sheffield-Moore, M., Aarsland, A. Wolfe, R.R. 2006. A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab 291, E381 387.
27. Koopman, R., Wagenmakers, A.J., Manders, R.J. et al. 2005. Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects. Am J Physiol Endocrinol Metab 288, E645 653.
28. Koryak, Y. 1999. The effects of long-term simulated microgravity on neuromuscular performance in men and women. Eur J Appl Physiol Occup Physiol 79, 168 175.
29. Kozlovskaya, I.B. Grigoriev, A.I. 2004. Russian system of countermeasures on board of the International Space Station (ISS): the first results. Acta Astronaut 55, 233 237.
30. Kozlovskaya, I.B., Grigoriev, A.I. Stepantzov, V.I. 1995. Countermeasure of the negative effects of weightlessness on physical systems in long-term space flights. Acta Astronaut 36, 661 668.
31. Kraemer, W.J., Patton, J.F., Gordon, S.E. et al. 1995. Compatibility of high-intensity strength and endurance training on hormonal and skeletal muscle adaptations. J Appl Physiol, 78, 976 989.
32. Leblanc, A.D., Schneider, V.S., Evans, H.J., Pientok, C., Rowe, R. Spector, E. 1992. Regional changes in muscle mass following 17 weeks of bed rest. J Appl Physiol 73, 2172 2178.
33. Leblanc, A., Lin, C., Shackelford, L. et al. 2000a. Muscle volume, MRI relaxation times (T2), and body composition after spaceflight. J Appl Physiol 89, 2158 2164.
34. Leblanc, A., Schneider, V., Shackelford, L. et al. 2000b. Bone mineral and lean tissue loss after long duration space flight. J Musculoskelet Neuronal Interact 1, 157 160.
35. Lee, S.M., Bennett, B.S., Hargens, A.R. et al. 1997. Upright exercise or supine lower body negative pressure exercise maintains exercise responses after bed rest. Med Sci Sports Exerc 29, 892 900.
36. Michel, E.L., Rummel, J.A. Sawin, C.F. 1975. Skylab experiment M-171 "Metabolic activity" results of the first manned mission. Acta Astronaut 2, 351 365.
37. Mittendorfer, B., Andersen, J.L., Plomgaard, P. et al. 2005. Protein synthesis rates in human muscles: neither anatomical location nor fibre-type composition are major determinants. J Physiol 563, 203 211.
38. Nakashima, K., Ishida, A., Yamazaki, M. Abe, H. 2005. Leucine suppresses myofibrillar proteolysis by down-regulating ubiquitin-proteasome pathway in chick skeletal muscles. Biochem Biophys Res Commun 336, 660 666.
39. Paddon-Jones, D., Sheffield-Moore, M., Urban, R.J. et al. 2004. Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bed rest. J Clin Endocrinol Metab 89, 4351 4358.
40. Phillips, S.M., Tipton, K.D., Aarsland, A., Wolf, S.E. Wolfe, R.R. 1997. Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol 273, E99 107.
41. Rambaut, P.C., Leach, C.S. Leonard, J.I. 1977. Observations in energy balance in man during spaceflight. Am J Physiol 233, R208 212.
42. Rennie, M.J., Wackerhage, H., Spangenburg, E.E. Booth, F.W. 2004. Control of the size of the human muscle mass. Annu Rev Physiol 66, 799 828.
43. Rieu, I., Balage, M., Sornet, C. et al. 2006. Leucine supplementation improves muscle protein synthesis in the elderly men independently of hyperaminoacidemia. J Physiol 575, 305 315.
44. Rummel, J.A., Sawin, C.F., Michel, E.L., Buderer, M.C. Thornton, W.T. 1975. Exercise and long duration space flight through 84 days. J Am Med Womens Assoc 30, 173 187.
45. Saltin, B. Gollnick, P.D. 1983. Skeletal muscle adaptability: significance for metabolism and performance. In : L.D. Peachey, R.H. Adrian S.R. Geiger (eds) Handbook of Physiology-Skeletal Muscle, pp. 555 631. American Physiological Society, Bethesda, MD.
46. Sandler, H. Winter, D.L. 1978. Physiological responses of women to simulated weightlessness: a review of the significant findings of the first female bed-rest study, pp. 1 87. National Aeronautics and Space Administration, Washington, DC.
47. Schneider, S.M., Amonette, W.E., Blazine, K. et al. 2003. Training with the International Space Station interim resistive exercise device. Med Sci Sports Exerc 35, 1935 1945.
48. Schulze, K., Gallagher, P. Trappe, S. 2002. Resistance training preserves skeletal muscle function during unloading in humans. Med Sci Sports Exerc 34, 303 313.
49. Shackelford, L.C., Leblanc, A.D., Driscoll, T.B. et al. 2004. Resistance exercise as a countermeasure to disuse-induced bone loss. J Appl Physiol 97, 119 129.
50. Sides, M.B., Vernikos, J., Convertino, V.A. et al. 2005. The Bellagio Report: cardiovascular risks of spaceflight: implications for the future of space travel. Aviat Space Environ Med 76, 877 895.
51. Smith, K., Barua, J.M., Watt, P.W., Scrimgeour, C.M. Rennie, M.J. 1992. Flooding with L-[1-13C]leucine stimulates human muscle protein incorporation of continuously infused L-[1-13C]valine. Am J Physiol 262, E372 376.
52. Smith, S.M., Zwart, S.R., Block, G., Rice, B.L. Davis-Street, J.E. 2005. The nutritional status of astronauts is altered after long-term space flight aboard the International Space Station. J Nutr 135, 437 443.
53. Stein, T.P., Leskiw, M.J., Schluter, M.D., Donaldson, M.R. Larina, I. 1999a. Protein kinetics during and after long-duration spaceflight on MIR. Am J Physiol, 276, E1014 1021.
54. Stein, T.P., Leskiw, M.J., Schluter, M.D. et al. 1999b. Energy expenditure and balance during spaceflight on the space shuttle. Am J Physiol 276, R1739 1748.
55. Stein, T.P., Schluter, M.D., Leskiw, M.J. Boden, G. 1999c. Attenuation of the protein wasting associated with bed rest by branched-chain amino acids. Nutrition 15, 656 660.
56. Stuart, C.A., Shangraw, R.E., Peters, E.J. Wolfe, R.R. 1990. Effect of dietary protein on bed-rest-related changes in whole-body-protein synthesis. Am J Clin Nutr, 52, 509 514.
57. Tesch, P.A., Trieschmann, J.T. Ekberg, A. 2004. Hypertrophy of chronically unloaded muscle subjected to resistance exercise. J Appl Physiol 96, 1451 1458.
58. Tischler, M.E., Desautels, M. Goldberg, A.L. 1982. Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle? J Biol Chem 257, 1613 1621.
59. Trappe, S.W., Trappe, T.A., Lee, G.A., Widrick, J.J., Costill, D.L. Fitts, R.H. 2001a. Comparison of a space shuttle flight (STS-78) and bed rest on human muscle function. J Appl Physiol 91, 57 64.
60. Trappe, T.A., Lindquist, D.M. Carrithers, J.A. 2001b. Muscle-specific atrophy of the quadriceps femoris with aging. J Appl Physiol, 90, 2070 2074.
61. Trappe, S., Trappe, T., Gallagher, P., Harber, M., Alkner, B. Tesch, P. 2004a. Human single muscle fibre function with 84 day bed-rest and resistance exercise. J Physiol 557, 501 513.
62. Trappe, T.A., Raue, U. Tesch, P.A. 2004b. Human soleus muscle protein synthesis following resistance exercise. Acta Physiol Scand 182, 189 196.
63. Trappe, S.W., Harber, M., Creer, A. et al. 2006a. Single muscle fiber adaptations with marathon training. J Appl Physiol 101, 721 727.
64. Trappe, T., Trappe, S., Lee, G., Widrick, J., Fitts, R. Costill, D. 2006b. Cardiorespiratory responses to physical work during and following 17 days of bed rest and spaceflight. J Appl Physiol 100, 951 957.
65. Watenpaugh, D.E. Hargens, A.R. 1996. The cardiovascular system in microgravity. In : M.J. Fregly C.M. Blatteis (eds) Handbook of Physiology, Section 4: Environmental Physiology, pp. 631 674. Oxford University Press, New York.
66. Watenpaugh, D.E., Ballard, R.E., Schneider, S.M. et al. 2000. Supine lower body negative pressure exercise during bed rest maintains upright exercise capacity. J Appl Physiol 89, 218 227.
67. Wolfe, R.R. 2002. Regulation of muscle protein by amino acids. J Nutr 132, 3219S 3224S.
68. Wolfe, R.R. Chinkes, D.L. 2005. Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis, pp. 299 420. Wiley-Liss, New Jersey.
69. Yasuda, N., Glover, E.I., Phillips, S.M., Isfort, R.J. Tarnopolsky, M.A. 2005. Sex-based differences in skeletal muscle function and morphology with short-term limb immobilization. J Appl Physiol 99, 1085 1092.