-
1
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344:1031-7.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
2
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001; 344:1038-42.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
-
3
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al. Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 2001; 344:1052-6.
-
(2001)
N Engl J Med
, vol.344
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
-
4
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri GD, von Mehren M, Blanke CD, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002; 347:472-80.
-
(2002)
N Engl J Med
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
Von Mehren, M.2
Blanke, C.D.3
-
5
-
-
0035960428
-
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: A phase 1 study
-
van Oosterom AT, Judson I, Verweij J, et al. Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase 1 study. Lancet 2001; 358:1421-3.
-
(2001)
Lancet
, vol.358
, pp. 1421-1423
-
-
Van Oosterom, A.T.1
Judson, I.2
Verweij, J.3
-
6
-
-
0021430551
-
The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor
-
Johnsson A, Heldin CH, Wasteson A, et al. The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor. Embo J 1984; 3:921-8.
-
(1984)
Embo J
, vol.3
, pp. 921-928
-
-
Johnsson, A.1
Heldin, C.H.2
Wasteson, A.3
-
7
-
-
0022447025
-
cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines
-
Betsholtz C, Johnsson A, Heldin CH, et al. cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines. Nature 1986; 320:695-9.
-
(1986)
Nature
, vol.320
, pp. 695-699
-
-
Betsholtz, C.1
Johnsson, A.2
Heldin, C.H.3
-
8
-
-
0033776193
-
PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
-
Li X, Ponten A, Aase K, et al. PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor. Nat Cell Biol 2000; 2:302-9.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 302-309
-
-
Li, X.1
Ponten, A.2
Aase, K.3
-
9
-
-
0025765803
-
SH2 and SH3 domains: Elements that control interactions of cytoplasmic signaling proteins
-
668-674
-
Koch CA, Anderson D, Moran MF, Ellis C, Pawson T. SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science 1991; 252:668-74.
-
(1991)
Science
, vol.252
-
-
Koch, C.A.1
Anderson, D.2
Moran, M.F.3
Ellis, C.4
Pawson, T.5
-
10
-
-
0022541219
-
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
-
Yarden Y, Escobedo JA, Kuang WJ, et al. Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature 1986; 323:226-32.
-
(1986)
Nature
, vol.323
, pp. 226-232
-
-
Yarden, Y.1
Escobedo, J.A.2
Kuang, W.J.3
-
11
-
-
0028429961
-
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
-
Wennstrom S, Hawkins P, Cooke F, et al. Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr Biol 1994; 4:385-93.
-
(1994)
Curr Biol
, vol.4
, pp. 385-393
-
-
Wennstrom, S.1
Hawkins, P.2
Cooke, F.3
-
12
-
-
0028089005
-
Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3′ kinase
-
Wennstrom S, Siegbahn A, Yokote K, et al. Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3′ kinase. Oncogene 1994; 9:651-60.
-
(1994)
Oncogene
, vol.9
, pp. 651-660
-
-
Wennstrom, S.1
Siegbahn, A.2
Yokote, K.3
-
14
-
-
0023505080
-
Polypeptide growth factors: Roles in normal and abnormal cell growth
-
Deuel TF. Polypeptide growth factors: roles in normal and abnormal cell growth. Annu Rev Cell Biol 1987; 3:443-92.
-
(1987)
Annu Rev Cell Biol
, vol.3
, pp. 443-492
-
-
Deuel, T.F.1
-
15
-
-
0033763567
-
Involvement of platelet-derived growth factor in disease: Development of specific antagonists
-
Ostman A, Heldin CH. Involvement of platelet-derived growth factor in disease: development of specific antagonists. Adv Cancer Res 2001; 80:1-38.
-
(2001)
Adv Cancer Res
, vol.80
, pp. 1-38
-
-
Ostman, A.1
Heldin, C.H.2
-
16
-
-
0027744498
-
Microvascular pericytes express platelet-derived growth factor-beta receptors in human healing wounds and colorectal adenocarcinoma
-
Sundberg C, Ljungstrom M, Lindmark G, Gerdin B, Rubin K. Microvascular pericytes express platelet-derived growth factor-beta receptors in human healing wounds and colorectal adenocarcinoma. Am J Pathol 1993; 143:1377-88.
-
(1993)
Am J Pathol
, vol.143
, pp. 1377-1388
-
-
Sundberg, C.1
Ljungstrom, M.2
Lindmark, G.3
Gerdin, B.4
Rubin, K.5
-
17
-
-
0035297541
-
Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
-
Pietras K, Ostman A, Sjoquist M, et al. Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res 2001; 61:2929-34.
-
(2001)
Cancer Res
, vol.61
, pp. 2929-2934
-
-
Pietras, K.1
Ostman, A.2
Sjoquist, M.3
-
18
-
-
0033613119
-
Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase signaling
-
Heuchel R, Berg A, Tallquist M, et al. Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase signaling. Proc Natl Acad Sci U S A 1999; 96:11410-5.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11410-11415
-
-
Heuchel, R.1
Berg, A.2
Tallquist, M.3
-
19
-
-
0026793260
-
Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors
-
Fleming TP, Saxena A, Clark WC, et al. Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors. Cancer Res 1992; 52:4550-3.
-
(1992)
Cancer Res
, vol.52
, pp. 4550-4553
-
-
Fleming, T.P.1
Saxena, A.2
Clark, W.C.3
-
20
-
-
0028911678
-
Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop
-
Guha A, Dashner K, Black PM, Wagner JA, Stiles CD. Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. Int J Cancer 1995; 60:168-73.
-
(1995)
Int J Cancer
, vol.60
, pp. 168-173
-
-
Guha, A.1
Dashner, K.2
Black, P.M.3
Wagner, J.A.4
Stiles, C.D.5
-
21
-
-
0026772431
-
Platelet-derived growth factor and its receptors in human glioma tissue: Expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops
-
Hermanson M, Funa K, Hartman M, et al. Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res 1992; 52:3213-9.
-
(1992)
Cancer Res
, vol.52
, pp. 3213-3219
-
-
Hermanson, M.1
Funa, K.2
Hartman, M.3
-
22
-
-
0029966854
-
The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways
-
Carroll M, Tomasson MH, Barker GF, Golub TR, Gilliland DG. The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways. Proc Natl Acad Sci U S A 1996; 93:14845-50.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14845-14850
-
-
Carroll, M.1
Tomasson, M.H.2
Barker, G.F.3
Golub, T.R.4
Gilliland, D.G.5
-
23
-
-
17144463437
-
A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein
-
Jousset C, Carron C, Boureux A, et al. A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein. Embo J 1997; 16:69-82.
-
(1997)
Embo J
, vol.16
, pp. 69-82
-
-
Jousset, C.1
Carron, C.2
Boureux, A.3
-
24
-
-
0031726412
-
Virocrine transformation: The intersection between viral transforming proteins and cellular signal transduction pathways
-
DiMaio D, Lai CC, Klein O. Virocrine transformation: the intersection between viral transforming proteins and cellular signal transduction pathways. Annu Rev Microbiol 1998; 52:397-421.
-
(1998)
Annu Rev Microbiol
, vol.52
, pp. 397-421
-
-
DiMaio, D.1
Lai, C.C.2
Klein, O.3
-
25
-
-
0031893168
-
Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages
-
Crosby JR, Seifert RA, Soriano P, Bowen-Pope DF. Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages. Nat Genet 1998; 18:385-8.
-
(1998)
Nat Genet
, vol.18
, pp. 385-388
-
-
Crosby, J.R.1
Seifert, R.A.2
Soriano, P.3
Bowen-Pope, D.F.4
-
26
-
-
0030756325
-
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
-
Lindahl P, Johansson BR, Leveen P, Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 1997; 277:242-5.
-
(1997)
Science
, vol.277
, pp. 242-245
-
-
Lindahl, P.1
Johansson, B.R.2
Leveen, P.3
Betsholtz, C.4
-
27
-
-
0029804549
-
Platelet-derived growth factor A and B chains and the alpha and beta receptors in prostatic intraepithelial neoplasia
-
Fudge K, Bostwick DG, Stearns ME. Platelet-derived growth factor A and B chains and the alpha and beta receptors in prostatic intraepithelial neoplasia. Prostate 1996; 29:282-6.
-
(1996)
Prostate
, vol.29
, pp. 282-286
-
-
Fudge, K.1
Bostwick, D.G.2
Stearns, M.E.3
-
28
-
-
0028455715
-
Immunohistochemistry analysis of platelet-derived growth factor A and B chains and platelet-derived growth factor alpha and beta receptor expression in benign prostatic hyperplasias and Gleason-graded human prostate adenocarcinomas
-
Fudge K, Wang CY, Stearns ME. Immunohistochemistry analysis of platelet-derived growth factor A and B chains and platelet-derived growth factor alpha and beta receptor expression in benign prostatic hyperplasias and Gleason-graded human prostate adenocarcinomas. Mod Pathol 1994; 7:549-54.
-
(1994)
Mod Pathol
, vol.7
, pp. 549-554
-
-
Fudge, K.1
Wang, C.Y.2
Stearns, M.E.3
-
29
-
-
0032877615
-
Tyrosine kinases expressed in vivo by human prostate cancer bone marrow metastases and loss of the type 1 insulin-like growth factor receptor
-
Chott A, Sun Z, Morganstern D, et al. Tyrosine kinases expressed in vivo by human prostate cancer bone marrow metastases and loss of the type 1 insulin-like growth factor receptor. Am J Pathol 1999; 155:1271-9.
-
(1999)
Am J Pathol
, vol.155
, pp. 1271-1279
-
-
Chott, A.1
Sun, Z.2
Morganstern, D.3
-
30
-
-
19044391072
-
Gene expression correlates of clinical prostate cancer behavior
-
Singh D, Febbo PG, Ross K, et al. Gene expression correlates of clinical prostate cancer behavior. Cancer Cell 2002; 1:203-9.
-
(2002)
Cancer Cell
, vol.1
, pp. 203-209
-
-
Singh, D.1
Febbo, P.G.2
Ross, K.3
-
31
-
-
0034900427
-
A multi-institutional phase ii study of SU101, a platelet-derived growth factor receptor inhibitor, for patients with hormone-refractory prostate cancer
-
Ko YJ, Small EJ, Kabbinavar F, et al. A multi-institutional phase ii study of SU101, a platelet-derived growth factor receptor inhibitor, for patients with hormone-refractory prostate cancer. Clin Cancer Res 2001; 7:800-5.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 800-805
-
-
Ko, Y.J.1
Small, E.J.2
Kabbinavar, F.3
-
32
-
-
0032747375
-
Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: Recommendations from the Prostate-Specific Antigen Working Group
-
Bubley GJ, Carducci M, Dahut W, et al. Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group. J Clin Oncol 1999; 17:3461-7.
-
(1999)
J Clin Oncol
, vol.17
, pp. 3461-3467
-
-
Bubley, G.J.1
Carducci, M.2
Dahut, W.3
-
33
-
-
0032538069
-
Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer
-
D'Amico AV, Whittington R, Malkowicz SB, et al. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. Jama 1998; 280:969-74.
-
(1998)
Jama
, vol.280
, pp. 969-974
-
-
D'Amico, A.V.1
Whittington, R.2
Malkowicz, S.B.3
|