Is there an effect of food on the biliary secretion of cyclosporine and three in vivo formed metabolites in a porcine model?

Journal of Drug Delivery Science and Technology

Volumn 17, Issue 4, 2007, Pages 253-258

  Persson, E M ^a   Nordgren, A ^b   Forsell, P ^b   Knutson, L ^b   Ohgren C ^c   Zacchari, H ^c   Abrahamsson, B ^c   Lennernas H ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Biliary secretion; Cyclosporine; Drug drug interaction; Food drug interaction; Liver transport bioavailability

Indexed keywords

CYCLOSPORIN; DRUG METABOLITE; GLYCOPROTEIN P; LIPID; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BILE SECRETION; CONTROLLED STUDY; DRUG EXCRETION; DRUG SOLUBILITY; FOOD; FOOD DRUG INTERACTION; IN VIVO STUDY; MALE; NONHUMAN; SWINE;

EID: 34548547213     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(07)50092-4     Document Type: Article

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