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ChemMedChem

Volumn 2, Issue 6, 2007, Pages 801-805

Structure-based calculation of binding affinities of α2A- adrenoceptor agonists

(4) Balogh, Balázs a,b Hetényi, Csaba a,b,c Keseru, Miklós György d Mátyus, Péter a,b

a SEMMELWEIS UNIVERSITY (Hungary)

b Szentagothai Knowledge Center (Hungary)

c UNIVERSITY OF TARTU (Estonia)

d GEDEON RICHTER LTD (Hungary)

Author keywords

Alpha2a adrenerg receptor; Docking; Free energy; Homology modeling; QSAR

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; LIGAND; RECEPTOR, ADRENERGIC, ALPHA 2A; RECEPTOR, ADRENERGIC, ALPHA-2A; RHODOPSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; CATTLE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; DRUG POTENTIATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

ADRENERGIC ALPHA-AGONISTS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATTLE; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, ALPHA-2; RHODOPSIN; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 34548522080 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200600251 Document Type: Article

Times cited : (4)

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