The effect of site-directed mutagenesis of two transmembrane serine residues on agonist-specific coupling of a cloned human α(2A)-adrenoceptor to adenylyl cyclase

British Journal of Pharmacology

Volumn 127, Issue 4, 1999, Pages 877-886

  Rudling, Jane E ^a   Kennedy, Karen ^a   Evans, Peter D ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Adenylyl cyclase; Cyclic AMP; In vitro mutagenesis; Noradrenaline; Octopamine; (2A) Adrenoceptor

Indexed keywords

ADENYLATE CYCLASE; ADRENERGIC RECEPTOR STIMULATING AGENT; ALANINE; ALPHA 2A ADRENERGIC RECEPTOR; CYCLIC AMP; NORADRENALIN; OCTOPAMINE; PERTUSSIS TOXIN; SERINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHO CELL; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

EID: 0033023546     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702614     Document Type: Article

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