Sensitization of central trigeminovascular neurons: Blockade by intravenous naproxen infusion

Neuroscience

Volumn 148, Issue 2, 2007, Pages 573-583

  Jakubowski, M ^a   Levy, D ^a   Kainz, V ^a   Zhang, X C ^a   Kosaras, B ^a   Burstein, R ^a,b  

^a HARVARD INSTITUTES OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

headache; migraine; nociception; NSAID; pain; trigeminal

Indexed keywords

NAPROXEN; TRIPTAN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL INNERVATION; CONTROLLED STUDY; DURA MATER; EMERGENCY CARE; IN VIVO STUDY; INFLAMMATION; INHIBITION KINETICS; MALE; MECHANICAL STIMULATION; MENINX; MIGRAINE; NOCICEPTIVE RECEPTOR; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION; SPINAL CORD DORSAL HORN; THERMAL STIMULATION; TREATMENT OUTCOME; TREATMENT RESPONSE; TRIGEMINAL NERVE;

ACTION POTENTIALS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DISEASE MODELS, ANIMAL; INFUSIONS, INTRAVENOUS; MALE; MIGRAINE DISORDERS; NAPROXEN; PAIN; PAIN THRESHOLD; PHYSICAL STIMULATION; POSTERIOR HORN CELLS; RATS; RATS, SPRAGUE-DAWLEY; SKIN; TIME FACTORS; TRIGEMINAL NERVE;

EID: 34548448564     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2007.04.064     Document Type: Article

References (43)

1. Andreeva L., and Rang H.P. Effect of bradykinin and prostaglandins on the release of calcitonin gene-related peptide-like immunoreactivity from the rat spinal cord in vitro. Br J Pharmacol 108 (1993) 185-190
2. Baba H., Kohno T., Moore K.A., and Woolf C.J. Direct activation of rat spinal dorsal horn neurons by prostaglandin E2. J Neurosci 21 (2001) 1750-1756
3. Beiche F., Brune K., Geisslinger G., and Goppelt-Struebe M. Expression of cyclooxygenase isoforms in the rat spinal cord and their regulation during adjuvant-induced arthritis. Inflamm Res 47 (1998) 482-487
4. Beiche F., Scheuerer S., Brune K., Geisslinger G., and Goppelt-Struebe M. Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation. FEBS Lett 390 (1996) 165-169
5. Burstein R., and Jakubowski M. Analgesic triptan action in an animal model of intracranial pain: A race against the development of central sensitization. Ann Neurol 55 (2004) 27-36
6. Burstein R., Jakubowski M., and Collins B. Defeating migraine pain with triptans: A race against the development of cutaneous allodynia. Ann Neurol 55 (2004) 19-26
7. Burstein R., Levy D., Jakubowski M., and Woolf C. Peripheral and central sensitization related to headache. In: Olesen P., et al. (Ed). The headaches Vol. 3 (2006), Lippincott Williams & Wilkins, Philadelphia 121-129
8. Burstein R., Yamamura H., Malick A., and Strassman A.M. Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons. J Neurophysiol 79 (1998) 964-982
9. Chapman V., and Dickenson A.H. The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat. Eur J Pharmacol 219 (1992) 427-433
10. Dirig D.M., and Yaksh T.L. In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin. Br J Pharmacol 126 (1999) 1333-1340
11. Ellrich J., Schepelmann K., Pawlak M., and Messlinger K. Acetylsalicylic acid inhibits meningeal nociception in rat. Pain 81 (1999) 7-14
12. Ferreira S.H., and Lorenzetti B.B. Intrathecal administration of prostaglandin E2 causes sensitization of the primary afferent neuron via the spinal release of glutamate. Inflammation Res 45 (1996) 499-502
13. Ghilardi J.R., Svensson C.I., Rogers S.D., Yaksh T.L., and Mantyh P.W. Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia. J Neurosci 24 (2004) 2727-2732
14. Jakubowski M., Levy D., Goor-Aryeh I., Collins B., Bajwa Z., and Burstein R. Terminating migraine with allodynia and ongoing central sensitization using parenteral administration of COX1/COX2 inhibitors. Headache 45 (2005) 850-861
15. Ji R.R., Kohno T., Moore K.A., and Woolf C.J. Central sensitization and LTP: do pain and memory share similar mechanisms?. Trends Neurosci 26 (2003) 696-705
16. Jung D., Mroszczak E., and Bynum L. Pharmacokinetics of ketorolac tromethamine in humans after intravenous, intramuscular and oral administration. Eur J Clin Pharmacol 35 (1988) 423-425
17. Kaube H., Hoskin K.L., and Goadsby P.J. Intravenous acetylsalicylic acid inhibits central trigeminal neurons in the dorsal horn of the upper cervical spinal cord in the cat. Headache 33 (1993) 541-544
18. Levy D., Jakubowski M., and Burstein R. Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT 1B/1D receptor agonists. Proc Natl Acad Sci U S A 101 (2004) 4274-4279
19. Levy D., and Strassman A.M. Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors. J Physiol 538 (2002) 483-493
20. Malmberg A.B., Hamberger A., and Hedner T. Effects of prostaglandin E2 and capsaicin on behavior and cerebrospinal fluid amino acid concentrations of unanesthetized rats: a microdialysis study. J Neurochem 65 (1995) 2185-2193
21. Malmberg A.B., and Yaksh T.L. Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat. J Pharmacol Exp Ther 263 (1992) 136-146
22. Malmberg A.B., and Yaksh T.L. Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats. J Neurosci 15 (1995) 2768-2776
23. Matsumura K., Watanabe Y., Onoe H., and Watanabe Y. Prostacyclin receptor in the brain and central terminals of the primary sensory neurons: an autoradiographic study using a stable prostacyclin analogue [3H]iloprost. Neuroscience 65 (1995) 493-503
24. McAleer S.D., Majid O., Venables E., Polack T., and Sheikh M.S. Pharmacokinetics and safety of ketorolac following single intranasal and intramuscular administration in healthy volunteers. J Clin Pharmacol 47 (2007) 13-18
25. Minami T., Nishihara I., Uda R., Ito S., Hyodo M., and Hayaishi O. Characterization of EP-receptor subtypes involved in allodynia and hyperalgesia induced by intrathecal administration of prostaglandin E2 to mice. Br J Pharmacol 112 (1994) 735-740
26. Neugebauer V., Geisslinger G., Rumenapp P., Weiretter F., Szelenyi I., Brune K., and Schaible H.G. Antinociceptive effects of R(-)- and S(+)-flurbiprofen on rat spinal dorsal horn neurons rendered hyperexcitable by an acute knee joint inflammation. J Pharmacol Exp Ther 275 (1995) 618-628
27. Pasloske K., Renaud R., Burger J., and Conlon P. Pharmacokinetics of ketorolac after intravenous and oral single dose administration in dogs. J Vet Pharmacol Ther 22 (1999) 314-319
28. Pitcher G.M., and Henry J.L. NSAID-induced cyclooxygenase inhibition differentially depresses long- lasting versus brief synaptically-elicited responses of rat spinal dorsal horn neurons in vivo. Pain 82 (1999) 173-186
29. Pitcher G.M., and Henry J.L. Meloxicam selectively depresses the afterdischarge of rat spinal dorsal horn neurones in response to noxious stimulation. Neurosci Lett 305 (2001) 45-48
30. Potrebic S., Ahn A.H., Skinner K., Fields H.L., and Basbaum A.I. Peptidergic nociceptors of both trigeminal and dorsal root ganglia express serotonin 1D receptors: implications for the selective antimigraine action of triptans. J Neurosci 23 (2003) 10988-10997
31. Samad T.A., Moore K.A., Sapirstein A., Billet S., Allchorne A., Poole S., Bonventre J.V., and Woolf C.J. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410 (2001) 471-475
32. Siegel S. Nonparametric statistics for the behavioral sciences (1956), McGraw-Hill Kogakusha, Tokyo
33. Steen K.H., Reeh P.W., Anton F., and Handwerker H.O. Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro. J Neurosci 12 (1992) 86-95
34. Steen K.H., Steen A.E., Kreysel H.W., and Reeh P.W. Inflammatory mediators potentiate pain induced by experimental tissue acidosis. Pain 66 (1996) 163-170
35. Steen K.H., Steen A.E., and Reeh P.W. A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro. J Neurosci 15 (1995) 3982-3989
36. Uda R., Horiguchi S., Ito S., Hyodo M., and Hayaishi O. Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2 alpha to conscious mice. Brain Res 510 (1990) 26-32
37. Vasko M.R. Prostaglandin-induced neuropeptide release from spinal cord. Prog Brain Res 104 (1995) 367-380
38. Watkins L.R., Milligan E.D., and Maier S.F. Glial activation: a driving force for pathological pain. Trends Neurosci 24 (2001) 450-455
39. Watkins L.R., Milligan E.D., and Maier S.F. Spinal cord glia: new players in pain. Pain 93 (2001) 201-205
40. Willingale H.L., Gardiner N.J., McLymont N., Giblett S., and Grubb B.D. Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability. Br J Pharmacol 122 (1997) 1593-1604
41. Yang L.C., Marsala M., and Yaksh T.L. Characterization of time course of spinal amino acids, citrulline and PGE2 release after carrageenan/kaolin-induced knee joint inflammation: a chronic microdialysis study. Pain 67 (1996) 345-354
42. You H.J., Morch C.D., Chen J., and Arendt-Nielsen L. Differential antinociceptive effects induced by a selective cyclooxygenase-2 inhibitor (SC-236) on dorsal horn neurons and spinal withdrawal reflexes in anesthetized spinal rats. Neuroscience 121 (2003) 459-472
43. Zar J.H. Biostatistical analysis (1998), Prentice-Hall, Englewood Cliffs