Comparative 1-substituted imidazole inhibition of cytochrome P450 isozyme-selective activities in human and mouse hepatic microsomes

Drug Metabolism Reviews

Volumn 39, Issue 2-3, 2007, Pages 309-322

  Franklin, Michael R ^a   Constance, Jonathan E ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

1 substituted imidazoles; Cytochrome P450(CYP) selective reactions; Human hepatic microsomes; Inhibition; Mouse hepatic microsomes

Indexed keywords

ADAMANTANE DERIVATIVE; BIFONAZOLE; CLOTRIMAZOLE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; ECONAZOLE; IMIDAZOLE; KETOCONAZOLE; MW 236; NAFIMIDONE; NITRAZEPAM; PROPRANOLOL DERIVATIVE; TUBULOZOLE T; UNCLASSIFIED DRUG; ZOXAZOLAMINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG METABOLISM; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; LIVER MICROSOME; MOUSE; NONHUMAN;

ADULT; AGED; ANIMALS; AROCLOR 1254; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FEMALE; HUMANS; IMIDAZOLES; ISOENZYMES; MALE; MICE; MICROSOMES, LIVER; MIDDLE AGED;

EID: 34548446239     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.1080/03602530701498570     Document Type: Article

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