The Nramp1 antimicrobial resistance gene segregates independently of resistance to virulent Mycobacterium tuberculosis

Immunology

Volumn 88, Issue 4, 1996, Pages 479-481

  Medina, E ^a   Rogerson, B J ^a   North, R J ^a  

^a TRUDEAU INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE SEGREGATION; HOST RESISTANCE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VIRULENCE;

EID: 0030016591     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-700.x     Document Type: Article

References (11)

1. SKAMENE E., GROS P., FORGET A., KONGSHAVN P.A.L., CHARLES C.S. & TAYLOR B.A. (1982) Genetic regulation of resistance to intracellular pathogens. Nature 297, 506.
2. MALO D., VOGAN K., VIDAL S. et al. (1994) Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites. Genomics 23, 51.
3. SAMBROOK J., FRITSCH E.F. & MANIATIS T. (1989) Molecular Cloning. In: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
4. GOVONI G., VIDAL S., CELLIER M., LEPAGE P., MALO D, & GROS P. (1995) Genomic structure, promoter sequence, and induction of expression of the mouse Nramp1 gene in macrophages. Genomics 27, 9.
5. PIERCE C.H., DUBOS R.J. & SCHAEFER W.B. (1953) Multiplication and survival of tubercle bacilli in the organs of mice. J Exp Med 97, 189.
6. HOPEWELL P.C. (1994) Overview of clinical tuberculosis. In: Tuberculosis: Pathogenesis, Protection and Control (ed. B.R. Bloom), p. 25, ASM Press, Washington, DC.
7. DUNN P.L. & NORTH R.J. (1995) Virulence ranking of some Mycobacterium tuberculosis and Mycobacterium bovis strains according to their ability to multiply in the lungs, induce lung pathology, and cause mortality in mice. Infect Immun 63, 3428.
8. MEDINA E. & NORTH R.J. (1996) Evidence inconsistent with a role for the Bcg gene (Nramp1) in resistance of mice to infection with virulent Mycobacterium tuberculosis. J Exp Med 183, 1045.
9. Wu D.Y., UGOZZOLI L., PAL B.K. & WALLACE R.B. (1989) Allele-specific enzymatic amplification of β-globin genomic DNA for diagnosis of sickle cell anemia. Proc Natl Acad Sci USA 86, 2757.
10. ERLICH H.A., GELFAND D. & SNINSKY J.J. (1991) Recent advances in the polymerase chain reaction. Science 252, 1643.
11. HS107 genes is not associated with gene conversion among family members. Int Immunol 7, 1225.