Intracerebroventricular but not intravenous interleukin-1β induces widespread vascular-mediated leukocyte infiltration and immune signal mRNA expression followed by brain-wide glial activation

Neuroscience

Volumn 112, Issue 3, 2002, Pages 731-749

  Proescholdt, M G ^a,b   Chakravarty, S ^a   Foster, J A ^a   Foti, S B ^a   Briley, E M ^a   Herkenham, M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b Bezirksklinikum Regensburg   (Germany)

Author keywords

Astrocytosis; Cerebrospinal fluid; Cyclooxygenase 2; Intercellular adhesion molecule 1; Meningitis; Monocyte chemoattractant protein 1; Nuclear factor B

Indexed keywords

CD45 ANTIGEN; CYCLOOXYGENASE 2; I KAPPA B ALPHA; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE SYNTHASE; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; GLIA CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LATERAL BRAIN VENTRICLE; LYMPHOCYTIC INFILTRATION; MALE; MICROGLIA; MONOCYTE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; VASCULAR ENDOTHELIUM;

ANIMALS; BIOLOGICAL MARKERS; BRAIN; CELL MOVEMENT; CEREBROVASCULAR CIRCULATION; CHEMOKINE CCL2; CYCLOOXYGENASE 2; I-KAPPA B PROTEINS; INJECTIONS, INTRAVENOUS; INJECTIONS, INTRAVENTRICULAR; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1; ISOENZYMES; LEUKOCYTES; MALE; NEUROGLIA; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0037025054     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00048-9     Document Type: Short Survey

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