-
1
-
-
0023256456
-
Prevalence of ras gene mutations in human colorectal cancers
-
Bos JL, Fearon ER, Hamilton SR, Verlaan-de Vries M, van Boom JH, van der Eb AJ, Vogelstein B. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987;327:293-7.
-
(1987)
Nature
, vol.327
, pp. 293-297
-
-
Bos, J.L.1
Fearon, E.R.2
Hamilton, S.R.3
Verlaan-de Vries, M.4
van Boom, J.H.5
van der Eb, A.J.6
Vogelstein, B.7
-
2
-
-
0024292722
-
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N, Perucho M. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 1988;53:549-54.
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
Martin, J.4
Arnheim, N.5
Perucho, M.6
-
3
-
-
0027733796
-
K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization
-
Hruban RH, van Mansfeld AD, Offerhaus GJ, van Weering DH, Allison DC, Goodman SN, Kensler TW, Bose KK, Cameron JL, Bos JL. K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization. Am J Pathol 1993;143:545-54.
-
(1993)
Am J Pathol
, vol.143
, pp. 545-554
-
-
Hruban, R.H.1
van Mansfeld, A.D.2
Offerhaus, G.J.3
van Weering, D.H.4
Allison, D.C.5
Goodman, S.N.6
Kensler, T.W.7
Bose, K.K.8
Cameron, J.L.9
Bos, J.L.10
-
4
-
-
0024560104
-
High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis
-
Lemoine NR, Mayall ES, Wyllie FS, Williams ED, Goyns M, Stringer B, Wynford-Thomas D. High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis. Oncogene 1989;4:159-64.
-
(1989)
Oncogene
, vol.4
, pp. 159-164
-
-
Lemoine, N.R.1
Mayall, E.S.2
Wyllie, F.S.3
Williams, E.D.4
Goyns, M.5
Stringer, B.6
Wynford-Thomas, D.7
-
5
-
-
0002616997
-
The molecular genetics of pancreatic adenocarcinoma
-
Neoptolemos JP, Lemoine NR. eds, Oxford: Black well Scientific Publications
-
Schutte M, Kern SE. The molecular genetics of pancreatic adenocarcinoma. In: Neoptolemos JP, Lemoine NR. eds. Pancreatic cancer. Oxford: Black well Scientific Publications, 1996;115-32.
-
(1996)
Pancreatic cancer
, pp. 115-132
-
-
Schutte, M.1
Kern, S.E.2
-
7
-
-
0028156004
-
In vitro reconstruction of tumour initiation in a human epithelium
-
Bond JA, Wyllie FS, Rowson J, Radulescu A, Wynford-Thomas D. In vitro reconstruction of tumour initiation in a human epithelium. Oncogene 1994;9:281-90.
-
(1994)
Oncogene
, vol.9
, pp. 281-290
-
-
Bond, J.A.1
Wyllie, F.S.2
Rowson, J.3
Radulescu, A.4
Wynford-Thomas, D.5
-
8
-
-
0033941559
-
Evidence for a telomere-independent "clock"; limiting RAS oncogene-driven proliferation of human thyroid epithelial cells
-
Jones CJ, Kipling D, Morris M, Hepburn P, Skinner J, Bounacer A, Wyllie FS, Ivan M, Bartek J, Wynford-Thomas D, Bond JA. Evidence for a telomere-independent "clock"; limiting RAS oncogene-driven proliferation of human thyroid epithelial cells. Mol Cell Biol 2000;20:5690-99.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5690-5699
-
-
Jones, C.J.1
Kipling, D.2
Morris, M.3
Hepburn, P.4
Skinner, J.5
Bounacer, A.6
Wyllie, F.S.7
Ivan, M.8
Bartek, J.9
Wynford-Thomas, D.10
Bond, J.A.11
-
9
-
-
0025939859
-
Complexities of the protein kinase C pathway
-
Blumberg M. Complexities of the protein kinase C pathway. Mol Carcinogen 1991;4:339-44.
-
(1991)
Mol Carcinogen
, vol.4
, pp. 339-344
-
-
Blumberg, M.1
-
10
-
-
0026568122
-
Effect of serum growth factors and phorbol ester on growth and survival of human thyroid epithelial cells expressing mutant ras
-
Bond J, Dawson T, Lemoine NR, Wynford-Thomas D. Effect of serum growth factors and phorbol ester on growth and survival of human thyroid epithelial cells expressing mutant ras. Mol Carcinogen 1992;5:129-35.
-
(1992)
Mol Carcinogen
, vol.5
, pp. 129-135
-
-
Bond, J.1
Dawson, T.2
Lemoine, N.R.3
Wynford-Thomas, D.4
-
11
-
-
0027715055
-
Toxicity of phorbol esters for human epithelial ceils expressing a mutant ras oncogene
-
Dawson T, Bond J, Eccles N, Wynford-Thomas D. Toxicity of phorbol esters for human epithelial ceils expressing a mutant ras oncogene. Mol Carcinogen 1993;8:280-9.
-
(1993)
Mol Carcinogen
, vol.8
, pp. 280-289
-
-
Dawson, T.1
Bond, J.2
Eccles, N.3
Wynford-Thomas, D.4
-
12
-
-
0031927057
-
Induction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: A potential therapeutic target
-
Hall-Jackson C, Jones T, Eccles N, Dawson T, Bond J, Gescher A, Wynford-Thomas D. Induction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: a potential therapeutic target. Br J Cancer 1998;78:641-51.
-
(1998)
Br J Cancer
, vol.78
, pp. 641-651
-
-
Hall-Jackson, C.1
Jones, T.2
Eccles, N.3
Dawson, T.4
Bond, J.5
Gescher, A.6
Wynford-Thomas, D.7
-
13
-
-
0028940099
-
Protein kinase C (PKC)-induced PKC degradation: A model for down-regulation
-
Parker PJ, Bosca L, Dekker L, Goode NT, Hajibagheri N, Hansra G. Protein kinase C (PKC)-induced PKC degradation: a model for down-regulation. Biochem Soc Trans 1995;23:153-5.
-
(1995)
Biochem Soc Trans
, vol.23
, pp. 153-155
-
-
Parker, P.J.1
Bosca, L.2
Dekker, L.3
Goode, N.T.4
Hajibagheri, N.5
Hansra, G.6
-
14
-
-
0025752547
-
Phorbol ester-induced tumor promotion by downregulation of protein kinase C
-
Droms KA, Malkinson AM. Phorbol ester-induced tumor promotion by downregulation of protein kinase C. Mol Carcinogen 1991;4:1-2.
-
(1991)
Mol Carcinogen
, vol.4
, pp. 1-2
-
-
Droms, K.A.1
Malkinson, A.M.2
-
15
-
-
0027370407
-
Prognostic indicators for survival after resection of pancreatic adenocarcinoma
-
Geer RJ, Brennan MF. Prognostic indicators for survival after resection of pancreatic adenocarcinoma. Am J Surg 1993;165:68-72.
-
(1993)
Am J Surg
, vol.165
, pp. 68-72
-
-
Geer, R.J.1
Brennan, M.F.2
-
16
-
-
0028962277
-
Dynamics of photoinduced cell plasma membrane injury
-
Thorpe WP, Toner M, Ezzell RM, Tompkins RG, Yarmush ML. Dynamics of photoinduced cell plasma membrane injury. Biophys J 1995;68:2198-206.
-
(1995)
Biophys J
, vol.68
, pp. 2198-2206
-
-
Thorpe, W.P.1
Toner, M.2
Ezzell, R.M.3
Tompkins, R.G.4
Yarmush, M.L.5
-
17
-
-
0034255474
-
Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy
-
Smith PJ, Blunt N, Wiltshire M, Hoy T, Teesdale-Spittle P, Craven MR, Watson JV, Amos WB, Errington RJ, Patterson LH. Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy. Cytometry 2000;40:280-91.
-
(2000)
Cytometry
, vol.40
, pp. 280-291
-
-
Smith, P.J.1
Blunt, N.2
Wiltshire, M.3
Hoy, T.4
Teesdale-Spittle, P.5
Craven, M.R.6
Watson, J.V.7
Amos, W.B.8
Errington, R.J.9
Patterson, L.H.10
-
18
-
-
0032912802
-
Control of replicattve lifespan in human cells: Barriers to clonal expansion intermediate between M1 senescence and M2 crisis
-
Bond J, Haughton M, Rowson J, Gtre V, Wynford-Thomas D, Wyllie F. Control of replicattve lifespan in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis. Mol Cell Biol 1999;19:3103-14.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3103-3114
-
-
Bond, J.1
Haughton, M.2
Rowson, J.3
Gtre, V.4
Wynford-Thomas, D.5
Wyllie, F.6
-
19
-
-
0034782530
-
Caspase activation during spontaneous and radiation-induced apoptosis in the murine intestine
-
Marshman E, Ottewell PD, Potten CS, Watson AJ. Caspase activation during spontaneous and radiation-induced apoptosis in the murine intestine. J Pathol 2001;195:285-92.
-
(2001)
J Pathol
, vol.195
, pp. 285-292
-
-
Marshman, E.1
Ottewell, P.D.2
Potten, C.S.3
Watson, A.J.4
-
20
-
-
0035207991
-
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4
-
Moore PS, Sipos B, Orlandini S, Sorio C, Real FX, Lemoine NR, Gress T, Bassi C, Kloppel G, Kalthoff H, Ungefroren H, Lohr M, et al. Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch 2001;439:798-802.
-
(2001)
Virchows Arch
, vol.439
, pp. 798-802
-
-
Moore, P.S.1
Sipos, B.2
Orlandini, S.3
Sorio, C.4
Real, F.X.5
Lemoine, N.R.6
Gress, T.7
Bassi, C.8
Kloppel, G.9
Kalthoff, H.10
Ungefroren, H.11
Lohr, M.12
-
21
-
-
0035254966
-
Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping
-
Sirivatanauksorn V, Sirivatanauksom Y, Gorman PA, Davidson JM, Sheer D, Moore PS, Scarpa A, Edwards PAW, Lemoine NR. Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping. Int J Cancer 2001;91:350-8.
-
(2001)
Int J Cancer
, vol.91
, pp. 350-358
-
-
Sirivatanauksorn, V.1
Sirivatanauksom, Y.2
Gorman, P.A.3
Davidson, J.M.4
Sheer, D.5
Moore, P.S.6
Scarpa, A.7
Edwards, P.A.W.8
Lemoine, N.R.9
-
22
-
-
0034697324
-
The lipophilicity of phorbol esters as a critical factor in determining the pattern of translocation of protein kinase C delta fused to green fluorescent protein
-
Wang QJ, Fang TW, Fenick D, Fenick D, Garfield S, Bienfait B, Marquez VE, Blumberg PM. The lipophilicity of phorbol esters as a critical factor in determining the pattern of translocation of protein kinase C delta fused to green fluorescent protein. J Biol Chem 2000;275:12136-46.
-
(2000)
J Biol Chem
, vol.275
, pp. 12136-12146
-
-
Wang, Q.J.1
Fang, T.W.2
Fenick, D.3
Fenick, D.4
Garfield, S.5
Bienfait, B.6
Marquez, V.E.7
Blumberg, P.M.8
-
23
-
-
0023749283
-
Bryostatin 1 activates protein kinase C and induces monocytic differentiation of HL-60 cells
-
Stone RM, Sariban E, Pettit GR, Kufe DW. Bryostatin 1 activates protein kinase C and induces monocytic differentiation of HL-60 cells. Blood 1988;72:208-13.
-
(1988)
Blood
, vol.72
, pp. 208-213
-
-
Stone, R.M.1
Sariban, E.2
Pettit, G.R.3
Kufe, D.W.4
-
24
-
-
0031760304
-
A phase 11 study of bryostatin 1 in metastatic malignant melanoma
-
Propper DJ, Macaulay V, O'Byrne KJ, Braybrooke JP, Wilner SM, Ganesan TS, Talbot DC, Harris AL. A phase 11 study of bryostatin 1 in metastatic malignant melanoma. Br J Cancer 1998;78:1337-41.
-
(1998)
Br J Cancer
, vol.78
, pp. 1337-1341
-
-
Propper, D.J.1
Macaulay, V.2
O'Byrne, K.J.3
Braybrooke, J.P.4
Wilner, S.M.5
Ganesan, T.S.6
Talbot, D.C.7
Harris, A.L.8
-
25
-
-
12944249449
-
Phase II trial of bryostatin 1 in patients with relapsed low-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia
-
Varterasian ML, Mohammad RM, Shurafa MS, Hulburd K, Pemberton PA, Rodriquez DH, Spadoni V, Eilender DS, Murgo A, Wall N, Dan M, Al-Katib AM. Phase II trial of bryostatin 1 in patients with relapsed low-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia. Clin Cancer Res 2000;6:825-8.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 825-828
-
-
Varterasian, M.L.1
Mohammad, R.M.2
Shurafa, M.S.3
Hulburd, K.4
Pemberton, P.A.5
Rodriquez, D.H.6
Spadoni, V.7
Eilender, D.S.8
Murgo, A.9
Wall, N.10
Dan, M.11
Al-Katib, A.M.12
-
26
-
-
0028205593
-
The role of protein kinase C isoenzymes in the growth inhibition caused by bryostatin 1 in human A549 lung and MCF-7 breast carcinoma cells
-
Stanwell C, Gescher A, Bradshaw TD, Pettit GR. The role of protein kinase C isoenzymes in the growth inhibition caused by bryostatin 1 in human A549 lung and MCF-7 breast carcinoma cells. Int J Cancer 1994;56:585-92.
-
(1994)
Int J Cancer
, vol.56
, pp. 585-592
-
-
Stanwell, C.1
Gescher, A.2
Bradshaw, T.D.3
Pettit, G.R.4
-
27
-
-
0024792279
-
Phosphorylation-regulated calmodulin binding to a prominent substrate for protein kinase C
-
Graff JM, Young TN, Johnson JD, Blackshear PJ. Phosphorylation-regulated calmodulin binding to a prominent substrate for protein kinase C. J Biol Chem 1989;264:21818-23.
-
(1989)
J Biol Chem
, vol.264
, pp. 21818-21823
-
-
Graff, J.M.1
Young, T.N.2
Johnson, J.D.3
Blackshear, P.J.4
-
28
-
-
0034776809
-
Protein kinase c isozymes, novel phorbol ester receptors and cancer chemotherapy
-
Barry OP, Kazanietz MG. Protein kinase c isozymes, novel phorbol ester receptors and cancer chemotherapy. Curr Pharm Des 2001;7:1725-44.
-
(2001)
Curr Pharm Des
, vol.7
, pp. 1725-1744
-
-
Barry, O.P.1
Kazanietz, M.G.2
-
29
-
-
0027936580
-
Phorbol esterinduced apoptosis is accompanied by NGFI-A and c-fos activation in androgen-sensitive prostate cancer cells
-
Day ML, Zhao X, Wu S, Swanson PE, Humphrey PA. Phorbol esterinduced apoptosis is accompanied by NGFI-A and c-fos activation in androgen-sensitive prostate cancer cells. Cell Growth Differ 1994;5:735-41.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 735-741
-
-
Day, M.L.1
Zhao, X.2
Wu, S.3
Swanson, P.E.4
Humphrey, P.A.5
-
30
-
-
12144289203
-
Inhibitory effect of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans-retinoic acid on the growth of LNCaP prostate tumours in immunodeficient mice
-
Zheng X, Chang RL, Cui X-X, Avila GE, Lee S, Lu YP, Lou YR, Shih WJ, Lin Y, Reuhl K, Newmark H, Rabson AB, et al. Inhibitory effect of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans-retinoic acid on the growth of LNCaP prostate tumours in immunodeficient mice. Cancer Res 2004;64:1811-20.
-
(2004)
Cancer Res
, vol.64
, pp. 1811-1820
-
-
Zheng, X.1
Chang, R.L.2
Cui, X.-X.3
Avila, G.E.4
Lee, S.5
Lu, Y.P.6
Lou, Y.R.7
Shih, W.J.8
Lin, Y.9
Reuhl, K.10
Newmark, H.11
Rabson, A.B.12
-
31
-
-
0035349737
-
Protein kinase C activation by PMA rapidly induces apoptosis through caspase-3/CPP32 and serine protease(s) in a gastric cancer cell line
-
Park IC, Park MJ, Rhee CH, Lee JI, Choe TB, Jang JJ, Lee SH, Hong SI. Protein kinase C activation by PMA rapidly induces apoptosis through caspase-3/CPP32 and serine protease(s) in a gastric cancer cell line. Int J Oncol 2001;18:1077-83.
-
(2001)
Int J Oncol
, vol.18
, pp. 1077-1083
-
-
Park, I.C.1
Park, M.J.2
Rhee, C.H.3
Lee, J.I.4
Choe, T.B.5
Jang, J.J.6
Lee, S.H.7
Hong, S.I.8
-
32
-
-
25644458432
-
Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenografts in immunodeficient mice
-
Avila GE, Zheng X, Cui XX, Ryan AD, Hansson A, Suh J, Rabson AB, Chang RL, Shih WJ, Lin Y, Crowell P, Lu YP, et al. Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenografts in immunodeficient mice. J Pharmacol Exp Ther 2005;315:170-87.
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 170-187
-
-
Avila, G.E.1
Zheng, X.2
Cui, X.X.3
Ryan, A.D.4
Hansson, A.5
Suh, J.6
Rabson, A.B.7
Chang, R.L.8
Shih, W.J.9
Lin, Y.10
Crowell, P.11
Lu, Y.P.12
-
33
-
-
33644526581
-
Overexpression of PKCΣ sensitizes LNCaP human prostate cells to induction of apoptosis by bryostatin 1
-
Powell CT, Yin L. Overexpression of PKCΣ sensitizes LNCaP human prostate cells to induction of apoptosis by bryostatin 1. Int J Cancer 2006;118:1572-6.
-
(2006)
Int J Cancer
, vol.118
, pp. 1572-1576
-
-
Powell, C.T.1
Yin, L.2
-
34
-
-
0035282926
-
Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features
-
Engedal N, Saatcioglu F. Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features. Prostate 2001;46:289-97.
-
(2001)
Prostate
, vol.46
, pp. 289-297
-
-
Engedal, N.1
Saatcioglu, F.2
-
35
-
-
0033828604
-
Activation of protein kinase C alpha inhibits growth of pancreatic cancer cells via p 21(cip)-mediated G1 arrest
-
Detjen KM, Brembeck FH, Welzel M, Kaiser A, Haller H, Weidenmann B, Rosewicz S. Activation of protein kinase C alpha inhibits growth of pancreatic cancer cells via p 21(cip)-mediated G1 arrest. J Cell Sci 2000;113:3025-35.
-
(2000)
J Cell Sci
, vol.113
, pp. 3025-3035
-
-
Detjen, K.M.1
Brembeck, F.H.2
Welzel, M.3
Kaiser, A.4
Haller, H.5
Weidenmann, B.6
Rosewicz, S.7
-
36
-
-
0034670173
-
Pharmacology of the receptors for the phorbol ester tumor promoters: Multiple receptors with different biochemical properties
-
Kazanietz MG, Caloca MJ, Eroles P, Fujii T, Garcia-Bermejo ML, Reilly M, Wang H. Pharmacology of the receptors for the phorbol ester tumor promoters: multiple receptors with different biochemical properties. Biochem Pharmacol 2000;60:1417-24.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1417-1424
-
-
Kazanietz, M.G.1
Caloca, M.J.2
Eroles, P.3
Fujii, T.4
Garcia-Bermejo, M.L.5
Reilly, M.6
Wang, H.7
-
37
-
-
29144529161
-
Targeting protein kinase C and "non-kinase" phorbol ester receptors: Emerging concepts and therapeutic implications
-
Kazanietz MG. Targeting protein kinase C and "non-kinase" phorbol ester receptors: emerging concepts and therapeutic implications. Biochim Biophys Acta 2005;1754:296-304.
-
(2005)
Biochim Biophys Acta
, vol.1754
, pp. 296-304
-
-
Kazanietz, M.G.1
-
38
-
-
0031784267
-
Regulation of Ras GRP via a phorbol ester-responsive Cl domain
-
Tognon CE, Kirk HE, Passmore LA, Whitehead IP, Der CJ, Kay RJ. Regulation of Ras GRP via a phorbol ester-responsive Cl domain. Mol Cell Biol 1998;18:6995-7008.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6995-7008
-
-
Tognon, C.E.1
Kirk, H.E.2
Passmore, L.A.3
Whitehead, I.P.4
Der, C.J.5
Kay, R.J.6
-
39
-
-
0030611884
-
Beta 2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters
-
Caloca MJ, Fernandez N, Lewin NE, Ching D, Modali R, Blumberg PM, Kazanietz MG. Beta 2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters. J Biol Chem 1997;272:26488-96.
-
(1997)
J Biol Chem
, vol.272
, pp. 26488-26496
-
-
Caloca, M.J.1
Fernandez, N.2
Lewin, N.E.3
Ching, D.4
Modali, R.5
Blumberg, P.M.6
Kazanietz, M.G.7
-
40
-
-
0036905264
-
Move over protein kinase C, you've got company: Alternative cellular effectors of diacylglycerol and phorbol esters
-
Brose N, Rosenmund C. Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters. J Cell Sci 2002;115:4399-411.
-
(2002)
J Cell Sci
, vol.115
, pp. 4399-4411
-
-
Brose, N.1
Rosenmund, C.2
-
41
-
-
0032948523
-
Human munc13 is a diacylglycerol receptor that induces apoptosis and may contribute to renal cell injury in hyperglycemia
-
Song Y, Ailenberg M, Silverman M. Human munc13 is a diacylglycerol receptor that induces apoptosis and may contribute to renal cell injury in hyperglycemia. Mol Biol Cell 1999;10:1609-19.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1609-1619
-
-
Song, Y.1
Ailenberg, M.2
Silverman, M.3
-
42
-
-
0032571139
-
Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells
-
Hamada K, Nakamura H, Oda T, Hirano T, Shimizu N, Utiyama H. Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells. Biochem Biophys Res Commun 1998;244:745-50.
-
(1998)
Biochem Biophys Res Commun
, vol.244
, pp. 745-750
-
-
Hamada, K.1
Nakamura, H.2
Oda, T.3
Hirano, T.4
Shimizu, N.5
Utiyama, H.6
-
43
-
-
0033541446
-
Activation of protein kinase C by phorbol esters modulates alpha 2beta 1 integrin on MCF-7 breast cancer cells
-
Rosfjord EC, Maemura M, Johnson MD, Torri JA, Akiyama SK, Woods VL, Jr, Dickson RB. Activation of protein kinase C by phorbol esters modulates alpha 2beta 1 integrin on MCF-7 breast cancer cells. Exp Cell Res 1999;248:260-71.
-
(1999)
Exp Cell Res
, vol.248
, pp. 260-271
-
-
Rosfjord, E.C.1
Maemura, M.2
Johnson, M.D.3
Torri, J.A.4
Akiyama, S.K.5
Woods Jr, V.L.6
Dickson, R.B.7
-
44
-
-
0036023408
-
Administration of a phorbol ester to patients with hematological malignancies: Preliminary results from a phase I clinical trial of 12-O-tetradecanoylphorbol-13-acetate
-
Strair RK, Schaar D, Goodell L, Aisner J, Chin KV, Eid J, Senzan R, Cui XX, Han ZT, Knox B, Rabson AB, Chang R, et al. Administration of a phorbol ester to patients with hematological malignancies: preliminary results from a phase I clinical trial of 12-O-tetradecanoylphorbol-13-acetate. Clin Cancer Res 2002;8:2512-18.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2512-2518
-
-
Strair, R.K.1
Schaar, D.2
Goodell, L.3
Aisner, J.4
Chin, K.V.5
Eid, J.6
Senzan, R.7
Cui, X.X.8
Han, Z.T.9
Knox, B.10
Rabson, A.B.11
Chang, R.12
-
45
-
-
0002997163
-
12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced increase in depressed white blood cell counts in patients treated with cytotoxic cancer chemotherapeutic drugs
-
Han ZT, Tong YK, He LM, Zhang Y, Sun JZ, Wang TY, Zhang H, Cui YL, Newmark HL, Conney AH, Chang RL. 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced increase in depressed white blood cell counts in patients treated with cytotoxic cancer chemotherapeutic drugs. Proc Natl Acad of Sci USA 1998a;95:5362-5.
-
(1998)
Proc Natl Acad of Sci USA
, vol.95
, pp. 5362-5365
-
-
Han, Z.T.1
Tong, Y.K.2
He, L.M.3
Zhang, Y.4
Sun, J.Z.5
Wang, T.Y.6
Zhang, H.7
Cui, Y.L.8
Newmark, H.L.9
Conney, A.H.10
Chang, R.L.11
-
46
-
-
0000356405
-
Effect of intravenous infusions of 12- O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: Preliminary studies on therapeutic efficacy and toxicity
-
Han ZT, Zhu XX, Yang RY, Sun JZ, Tian GF, Liu XJ, Cao GS, Newmark HL, Conney AH, Chang RL. Effect of intravenous infusions of 12- O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: preliminary studies on therapeutic efficacy and toxicity. Proc Natl Acad of Sci USA 1998b;95:5357-61.
-
(1998)
Proc Natl Acad of Sci USA
, vol.95
, pp. 5357-5361
-
-
Han, Z.T.1
Zhu, X.X.2
Yang, R.Y.3
Sun, J.Z.4
Tian, G.F.5
Liu, X.J.6
Cao, G.S.7
Newmark, H.L.8
Conney, A.H.9
Chang, R.L.10
-
47
-
-
0042229371
-
A sensitive bioassay for measuring blood levels of 12-O-Tetradecanoylphorbol-13- acetate(TPA) in patients: Preliminary pharmacokinetic studies
-
Cui XX, Chang RL, Zheng X, Woodward D, Strair R, Conney AH. A sensitive bioassay for measuring blood levels of 12-O-Tetradecanoylphorbol-13- acetate(TPA) in patients: preliminary pharmacokinetic studies. Oncol Res 2002;13:169-74.
-
(2002)
Oncol Res
, vol.13
, pp. 169-174
-
-
Cui, X.X.1
Chang, R.L.2
Zheng, X.3
Woodward, D.4
Strair, R.5
Conney, A.H.6
-
48
-
-
33645731655
-
A phase 1 clinical trial of 12 O-tetradecanoylphorbol-13-acetate for patients with relapsed/refractory malignancies
-
Schaar D, Goodell L, Aisner J, Cui XX, Han ZT, Chang R, Martin J, Grospe S, Dudek L, Riley J, Manago J, Lin Y, et al. A phase 1 clinical trial of 12 O-tetradecanoylphorbol-13-acetate for patients with relapsed/refractory malignancies. Cancer Chemother Pharmacol 2006;57:789-95.
-
(2006)
Cancer Chemother Pharmacol
, vol.57
, pp. 789-795
-
-
Schaar, D.1
Goodell, L.2
Aisner, J.3
Cui, X.X.4
Han, Z.T.5
Chang, R.6
Martin, J.7
Grospe, S.8
Dudek, L.9
Riley, J.10
Manago, J.11
Lin, Y.12
|