Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 830, Issue 2, 2006, Pages 270-277

  Smalley, James ^a   Kadiyala, Pathanjali ^a   Xin, Baomin ^a   Balimane, Praveen ^a   Olah, Timothy ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Caco 2; LC MS MS analysis; On line extraction; Tandem mass spectrometry; Turbulent flow chromatography

Indexed keywords

EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATHEMATICAL MODELS; THROUGHPUT; TURBULENT FLOW;

CACO-2; LC-MS/MS ANALYSIS; ON-LINE EXTRACTION; TANDEM MASS SPECTROMETRY; TURBULENT FLOW CHROMATOGRAPHY;

MASS SPECTROMETRY;

DEXAMETHASONE; ETOPOSIDE; FUROSEMIDE; GLYCOPROTEIN P; METOPROLOL; NADOLOL; PROPRANOLOL; QUINIDINE; RHODAMINE 123; SALAZOSULFAPYRIDINE; VERAPAMIL;

ACCURACY; ARTICLE; CELL ASSAY; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN INTERACTION; RELIABILITY; TANDEM MASS SPECTROMETRY; TURBULENT FLOW; ULTRAVIOLET RADIATION;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEXAMETHASONE; ETOPOSIDE; FUROSEMIDE; HUMANS; METOPROLOL; NADOLOL; PHARMACEUTICAL PREPARATIONS; PROPRANOLOL; QUINIDINE; RHODAMINE 123; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFASALAZINE; VERAPAMIL;

EID: 30444438697     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.11.006     Document Type: Article

References (24)

1. J. Lin Adv. Drug Deliv. Rev. 55 2003 53
2. J. Lin, and M. Yamazaki Clin. Pharmacokinet. 42 2003 59
3. C. Matheny, M. Lamb, K. Brouwer, and G. Pollak Pharmacotherapy 21 2001 778
4. A. Sparreboom, J. Asperen, U. Mayer, A. Schinkel, J. Smit, D. Meijer, P. Borst, W. Nooijen, J. Beijen, and O. Tellingen Proc. Natl. Acad. Sci. U.S.A. 94 1997 2031
5. J. Polli, J. Jerrett, J. Studenberg, J. Humphreys, S. Dennis, K. Brower, and J. Wooley Pharm. Res. 16 1999 1206
6. T. Watanabe, S. Miyauchi, Y. Sawada, T. Iga, M. Hanano, M. Inaba, and Y. Sugiyama J. Hepatol. 16 1992 77
7. E. Leahey, J. Reiffel, R. Drusin, R. Heissenbuttel, W. Lovejoy, and J. Bigger J. Am. Med. Assoc. 240 1978 533
8. M. Markowska, R. Oberle, S. Juzwin, C.-P. Hsu, M. Gryszkiewicz, and A. Streeter J. Pharm. Toxicol. Methods 46 2001 51
9. H.Z. Bu, M. Poglod, R. Micetich, and J. Khan Rapid Commun. Mass Spectrom. 14 2000 523
10. P. Balimane, K. Patel, A. Marino, and S. Chong Eur. J. Pharm. Biopharm. 58 2004 99
11. X. Xu, K. Han, H. Song, and M.-W. Lo J. Chromatogr. B 814 2005 29
12. K. Hakala, L. Laitinen, A. Kaukonen, J. Hirvonen, R. Kostiainen, and T. Kotiaho Anal. Chem. 75 2003 5969
13. Y.J. Xue, K. Turner, J. Meeker, J. Pursley, M. Arnold, and S. Unger J. Chromatogr. B 795 2003 215
14. S. Wu, J. Xing, A. Apedo, D. Wang-Iverson, T. Olah, and A. Tymiak Rapid Commun. Mass Spectrom. 18 2004 2531
15. J. Ayrton, G. Dear, W. Leavens, D. Mallett, and R. Plumb Rapid Commun. Mass Spectrom. 11 1997 1953
16. A. Liesener, and U. Karst J. Sep. Sci. 28 2005 1658
17. S. Zhou, H. Zhou, M. Larson, D. Miller, D. Mao, X. Jiang, and W. Naidong Rapid Commun. Mass Spectrom. 19 2005 2144
18. S. Hsieh, T. Tobien, K. Koch, and J. Dunn Rapid Commun. Mass Spectrom. 18 2004 285
19. R. Grant, C. Cameron, and S. Mackenzie-McMurter Rapid Commun. Mass Spectrom. 16 2002 1785
20. X. Xu, K. Yan, H. Song, and M. Lo J. Chromatogr. B 814 2005 29
21. L. Laitinen, H. Kangas, A. Kaukonen, K. Hakala, T. Kotiaho, R. Kostiainen, and J. Hirvonen Pharm. Res. 20 2003 187
22. C. Tannergren, P. Langguth, and K.J. Hoffmann Pharmazie 56 2001 337
23. Z. Wang, C. Hop, K. Leung, and J. Pang J. Mass Spectrom. 35 2000 71
24. H. Bu, M. Poglod, R. Micetich, and J. Khan Rapid Commun. Mass Spectrom. 14 2000 523