Statin-induced apoptosis linked with membrane farnesylated Ras small G protein depletion, rather than geranylated Rho protein

Journal of Pharmacy and Pharmacology

Volumn 57, Issue 11, 2005, Pages 1475-1484

  Matzno, Sumio ^a   Yasuda, Shinya ^a   Juman, Sachiko ^a   Yamamoto, Yukiko ^a   Nagareya Ishida, Noriko ^a   Tazuya Murayama, Keiko ^b   Nakabayashi, Toshikatsu ^a   Matsuyama, Kenji ^a  

^a MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

^b DAIICHI UNIVERSITY OF PHARMACY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; CASPASE 8; CERIVASTATIN; FLUINDOSTATIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PRAVASTATIN; RAS PROTEIN; RHO FACTOR; SIMVASTATIN; CASP8 PROTEIN, RAT; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INDOLE DERIVATIVE; MEMBRANE LIPID; MONOUNSATURATED FATTY ACID; PYRIDINE DERIVATIVE; PYRROLE DERIVATIVE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; DISEASE COURSE; ENZYME ACTIVITY; FLOW CYTOMETRY; IMMUNOBLOTTING; MOUSE; MYOBLAST; NONHUMAN; RHABDOMYOLYSIS; ANIMAL; CELL LINE; DRUG EFFECT; FLUORESCENCE MICROSCOPY; METABOLISM; PROTEIN PROCESSING; RAT; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; CASPASE 8; CELL LINE; FATTY ACIDS, MONOUNSATURATED; FLOW CYTOMETRY; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INDOLES; MEMBRANE LIPIDS; MICROSCOPY, FLUORESCENCE; MYOBLASTS, SKELETAL; PROTEIN ISOPRENYLATION; PYRIDINES; PYRROLES; RAS PROTEINS; RATS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 34548106601     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.57.11.0014     Document Type: Article

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