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Volumn 6, Issue 4, 2007, Pages 348-357

Regulating regulatory T cells to achieve transplant tolerance

Author keywords

Apoptosis; Co stimulation; HDAC inhibitor; Nur77; Regulatory T cells; Transplant tolerance

Indexed keywords

6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; ADENOSINE; BASILIXIMAB; CD134 ANTIGEN; CD27 ANTIGEN; CD30 ANTIGEN; COLECALCIFEROL; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DEXAMETHASONE; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; INTERLEUKIN 10; INTERLEUKIN 2; LACTACYSTIN; MONOCLONAL ANTIBODY; NUCLEAR RECEPTOR NUR77; OX40 L; PC 61; RAPAMYCIN; RETINOIC ACID; THAPSIGARGIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRICHOSTATIN A; UNCLASSIFIED DRUG;

EID: 34548079870     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (21)

References (58)
  • 1
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003;3:199-210.
    • (2003) Nat Rev Immunol , vol.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2
  • 3
    • 33746189406 scopus 로고    scopus 로고
    • FOXP3 and NFAT: Partners in tolerance
    • Rudensky AY, Gavin M, Zheng Y. FOXP3 and NFAT: partners in tolerance. Cell 2006;126:253-256.
    • (2006) Cell , vol.126 , pp. 253-256
    • Rudensky, A.Y.1    Gavin, M.2    Zheng, Y.3
  • 4
    • 27844498708 scopus 로고    scopus 로고
    • Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions
    • Lam AL, Pazin DE, Sullivan BA. Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions. Chromosoma 2005;114:242-251.
    • (2005) Chromosoma , vol.114 , pp. 242-251
    • Lam, A.L.1    Pazin, D.E.2    Sullivan, B.A.3
  • 6
    • 13744260173 scopus 로고    scopus 로고
    • Reversible histone acetylation and deacetylation mediate genome-wide, promoter-dependent and locus-specific changes in gene expression during plant development
    • Tian L, Fong MP, Wang JJ, Wei NE, Jiang H, Doerge RW, et al. Reversible histone acetylation and deacetylation mediate genome-wide, promoter-dependent and locus-specific changes in gene expression during plant development. Genetics 2005;169:337-345.
    • (2005) Genetics , vol.169 , pp. 337-345
    • Tian, L.1    Fong, M.P.2    Wang, J.J.3    Wei, N.E.4    Jiang, H.5    Doerge, R.W.6
  • 7
    • 30944470262 scopus 로고    scopus 로고
    • Histone deacetylases as transcriptional activators? Role reversal in inducible gene regulation
    • Nusinzon I, Horvath CM. Histone deacetylases as transcriptional activators? Role reversal in inducible gene regulation. Sci STKE 2005;2005:re11.
    • (2005) Sci STKE 2005
    • Nusinzon, I.1    Horvath, C.M.2
  • 8
    • 28044471827 scopus 로고    scopus 로고
    • Acetylation and deacetylation of non-histone proteins
    • Glozak MA, Sengupta N, Zhang X, Seto E. Acetylation and deacetylation of non-histone proteins. Gene 2005;363: 15-23.
    • (2005) Gene , vol.363 , pp. 15-23
    • Glozak, M.A.1    Sengupta, N.2    Zhang, X.3    Seto, E.4
  • 9
    • 33750496904 scopus 로고    scopus 로고
    • Targeting histone deacetylases for the treatment of cancer and inflammatory diseases
    • Huang L. Targeting histone deacetylases for the treatment of cancer and inflammatory diseases. J Cell Physiol 2006;209:611-616.
    • (2006) J Cell Physiol , vol.209 , pp. 611-616
    • Huang, L.1
  • 12
    • 0037100384 scopus 로고    scopus 로고
    • Modulation of Fas-dependent apoptosis: A dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells
    • Banz A, Pontoux C, Papiernik M. Modulation of Fas-dependent apoptosis: a dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells. J Immunol. 2002;169:750-757.
    • (2002) J Immunol , vol.169 , pp. 750-757
    • Banz, A.1    Pontoux, C.2    Papiernik, M.3
  • 13
    • 33751175422 scopus 로고    scopus 로고
    • Naive regulatory T cells: A novel subpopulation defined by resistance toward CD95L-mediated cell death
    • Fritzsching B, Oberle N, Pauly E, Geffers R, Buer J, Poschl J, et al. Naive regulatory T cells: a novel subpopulation defined by resistance toward CD95L-mediated cell death. Blood 2006;108:3371-3378.
    • (2006) Blood , vol.108 , pp. 3371-3378
    • Fritzsching, B.1    Oberle, N.2    Pauly, E.3    Geffers, R.4    Buer, J.5    Poschl, J.6
  • 14
    • 0348047537 scopus 로고    scopus 로고
    • The main function of IL-2 is to promote the development of T regulatory cells
    • i
    • Malek TR. The main function of IL-2 is to promote the development of T regulatory cells. J Leukoc Biol 2003;74: 961-965. i
    • (2003) J Leukoc Biol , vol.74 , pp. 961-965
    • Malek, T.R.1
  • 15
    • 23844435586 scopus 로고    scopus 로고
    • + regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: A role for P2X7 receptors
    • + regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors. J Immunol 2005;175:3075-3083.
    • (2005) J Immunol , vol.175 , pp. 3075-3083
    • Aswad, F.1    Kawamura, H.2    Dennert, G.3
  • 17
    • 0028008513 scopus 로고    scopus 로고
    • Woronicz JD, Calnan B, Ngo V, Winoto A. Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature 1994;367:277-281. i
    • Woronicz JD, Calnan B, Ngo V, Winoto A. Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature 1994;367:277-281. i
  • 18
    • 0027976193 scopus 로고    scopus 로고
    • Liu ZG, Smith SW, McLaughlin KA, Schwartz LM, Osborne BA. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature 1994;367:281-284. i
    • Liu ZG, Smith SW, McLaughlin KA, Schwartz LM, Osborne BA. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature 1994;367:281-284. i
  • 19
    • 0028807837 scopus 로고
    • A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection
    • Calnan BJ, Szychowski S, Chan FK, Cado D, Winoto A. A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection. Immunity 1995;3:273-282.
    • (1995) Immunity , vol.3 , pp. 273-282
    • Calnan, B.J.1    Szychowski, S.2    Chan, F.K.3    Cado, D.4    Winoto, A.5
  • 20
    • 0029952319 scopus 로고    scopus 로고
    • Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway
    • Weih F, Ryseck RP, Chen L, Bravo R. Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway. Proc Natl Acad Sci U S A 1996;93:5533-5538.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5533-5538
    • Weih, F.1    Ryseck, R.P.2    Chen, L.3    Bravo, R.4
  • 21
    • 0029914914 scopus 로고    scopus 로고
    • Inhibition of Nur77/ Nurr1 leads to inefficient clonal deletion of self-reactive T cells
    • Zhou T, Cheng J, Yang P, Wang Z, Liu C, Su X, et al. Inhibition of Nur77/ Nurr1 leads to inefficient clonal deletion of self-reactive T cells. J Exp Med 1996;183:1879-1892.
    • (1996) J Exp Med , vol.183 , pp. 1879-1892
    • Zhou, T.1    Cheng, J.2    Yang, P.3    Wang, Z.4    Liu, C.5    Su, X.6
  • 22
    • 0029056318 scopus 로고
    • Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)
    • Lee SL, Wesselschmidt RL, Linette GP, Kanagawa O, Russell JH, Milbrandt J. Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77). Science 1995;269:532-535.
    • (1995) Science , vol.269 , pp. 532-535
    • Lee, S.L.1    Wesselschmidt, R.L.2    Linette, G.P.3    Kanagawa, O.4    Russell, J.H.5    Milbrandt, J.6
  • 24
    • 0034192212 scopus 로고    scopus 로고
    • Retinoic acid and its receptors repress the expression and transactivation functions of Nur77: A possible mechanism for the inhibition of apoptosis by retinoic acid
    • Kang HJ, Song MR, Lee SK, Shin EC, Choi YH, Kim SJ, et al. Retinoic acid and its receptors repress the expression and transactivation functions of Nur77: a possible mechanism for the inhibition of apoptosis by retinoic acid. Exp Cell Res 2000;256:545-554.
    • (2000) Exp Cell Res , vol.256 , pp. 545-554
    • Kang, H.J.1    Song, M.R.2    Lee, S.K.3    Shin, E.C.4    Choi, Y.H.5    Kim, S.J.6
  • 25
    • 0342995776 scopus 로고    scopus 로고
    • Activation-induced apoptosis and cell surface expression of Fas (CD95) ligand are reciprocally regulated by retinoic acid receptor alpha and gamma and involve nur77 in T cells
    • Toth R, Szegezdi E, Reichert U, Bernardon JM, Michel S, Ancian P, et al. Activation-induced apoptosis and cell surface expression of Fas (CD95) ligand are reciprocally regulated by retinoic acid receptor alpha and gamma and involve nur77 in T cells. Eur J Immunol 2001;31:1382-1391.
    • (2001) Eur J Immunol , vol.31 , pp. 1382-1391
    • Toth, R.1    Szegezdi, E.2    Reichert, U.3    Bernardon, J.M.4    Michel, S.5    Ancian, P.6
  • 26
    • 0031830509 scopus 로고    scopus 로고
    • Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines
    • Li Y, Lin B, Agadir A, Liu R, Dawson MI, Reed JC, et al. Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol 1998;18:4719-4731.
    • (1998) Mol Cell Biol , vol.18 , pp. 4719-4731
    • Li, Y.1    Lin, B.2    Agadir, A.3    Liu, R.4    Dawson, M.I.5    Reed, J.C.6
  • 27
    • 33745415195 scopus 로고    scopus 로고
    • Adenosine A2A receptor-mediated cell death of mouse thymocytes involves adenylate cyclase and Bim and is negatively regulated by Nur77
    • Kiss I, Oskolas H, Toth R, Bouillet P, Toth K, Fulop A, et al. Adenosine A2A receptor-mediated cell death of mouse thymocytes involves adenylate cyclase and Bim and is negatively regulated by Nur77 Eur J Immunol 2006;36:1559-15571.
    • (2006) Eur J Immunol , vol.36 , pp. 1559-15571
    • Kiss, I.1    Oskolas, H.2    Toth, R.3    Bouillet, P.4    Toth, K.5    Fulop, A.6
  • 28
    • 0037094470 scopus 로고    scopus 로고
    • Identification by DNA macroarray of nur77 as a gene induced by di-n-butyltin dichloride: Its role in organotin-induced apoptosis
    • Gennari A, Bleumink R, Viviani B, Galli CL, Marinovich M, Pieters R, et al. Identification by DNA macroarray of nur77 as a gene induced by di-n-butyltin dichloride: its role in organotin-induced apoptosis. Toxicol Appl Pharmacol 2002;181:27-31.
    • (2002) Toxicol Appl Pharmacol , vol.181 , pp. 27-31
    • Gennari, A.1    Bleumink, R.2    Viviani, B.3    Galli, C.L.4    Marinovich, M.5    Pieters, R.6
  • 29
    • 0034970465 scopus 로고    scopus 로고
    • Thapsigargin-induced apoptosis involves Cabin1-MEF2-mediated induction of Nur77
    • Liu W, Youn HD, Liu JO. Thapsigargin-induced apoptosis involves Cabin1-MEF2-mediated induction of Nur77. Eur J Immunol 2001;31:1757-1764.
    • (2001) Eur J Immunol , vol.31 , pp. 1757-1764
    • Liu, W.1    Youn, H.D.2    Liu, J.O.3
  • 31
    • 0035980060 scopus 로고    scopus 로고
    • Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis
    • Masuyama N, Oishi K, Mori Y, Ueno T, Takahama Y, Gotoh Y. Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis. J Biol Chem 2001;276:32799-32805.
    • (2001) J Biol Chem , vol.276 , pp. 32799-32805
    • Masuyama, N.1    Oishi, K.2    Mori, Y.3    Ueno, T.4    Takahama, Y.5    Gotoh, Y.6
  • 33
    • 0028812358 scopus 로고
    • Cyclosporin A blocks apoptosis by inhibiting the DNA binding activity of the transcription factor Nur77
    • Yazdanbakhsh K, Choi JW, Li Y, Lau LF, Choi Y. Cyclosporin A blocks apoptosis by inhibiting the DNA binding activity of the transcription factor Nur77. Proc Natl Acad Sci U S A 1995;92:437-441.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 437-441
    • Yazdanbakhsh, K.1    Choi, J.W.2    Li, Y.3    Lau, L.F.4    Choi, Y.5
  • 35
    • 33745235090 scopus 로고    scopus 로고
    • Transplant tolerance in non-human primates: Progress, current challenges and unmet needs
    • Kean LS, Gangappa S, Pearson TC, Larsen CP. Transplant tolerance in non-human primates: progress, current challenges and unmet needs. Am J Transplant 2006;6:884-893.
    • (2006) Am J Transplant , vol.6 , pp. 884-893
    • Kean, L.S.1    Gangappa, S.2    Pearson, T.C.3    Larsen, C.P.4
  • 37
    • 13944260538 scopus 로고    scopus 로고
    • CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
    • Tai X, Cowan M, Feigenbaum L, Singer A. CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. Nat Immunol 2005;6:152-162.
    • (2005) Nat Immunol , vol.6 , pp. 152-162
    • Tai, X.1    Cowan, M.2    Feigenbaum, L.3    Singer, A.4
  • 39
    • 3142708571 scopus 로고    scopus 로고
    • Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
    • Paust S, Lu L, McCarty N, Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci U S A 2004;101:10398-10403.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10398-10403
    • Paust, S.1    Lu, L.2    McCarty, N.3    Cantor, H.4
  • 40
    • 17644389199 scopus 로고    scopus 로고
    • Watts TH. TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 2005;23:23-68.
    • Watts TH. TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 2005;23:23-68.
  • 43
    • 0345598872 scopus 로고    scopus 로고
    • Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells
    • Tone M, Tone Y, Adams E, Yates SF, Frewin MR, Cobbold SP, et al. Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc Natl Acad Sci U S A 2003;100:15059-15064
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15059-15064
    • Tone, M.1    Tone, Y.2    Adams, E.3    Yates, S.F.4    Frewin, M.R.5    Cobbold, S.P.6
  • 44
    • 2442429448 scopus 로고    scopus 로고
    • Cutting edge: The natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression
    • Ji HB, Liao G, Faubion WA, Abadia-Molina AC, Cozzo C, Laroux FS, et al. Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression. J Immunol 2004; 172:5823-5827.
    • (2004) J Immunol , vol.172 , pp. 5823-5827
    • Ji, H.B.1    Liao, G.2    Faubion, W.A.3    Abadia-Molina, A.C.4    Cozzo, C.5    Laroux, F.S.6
  • 49
    • 19944433635 scopus 로고    scopus 로고
    • B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator
    • Sedy JR, Gavrieli M, Potter KG, Hurchla MA, Lindsley RC, Hildner K, et al. B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator. Nat Immunol 2005;6:90-98.
    • (2005) Nat Immunol , vol.6 , pp. 90-98
    • Sedy, J.R.1    Gavrieli, M.2    Potter, K.G.3    Hurchla, M.A.4    Lindsley, R.C.5    Hildner, K.6
  • 50
    • 19544383401 scopus 로고    scopus 로고
    • The evolving crosstalk between co-stimulatory and co-inhibitory receptors: HVEM-BTLA
    • Croft M. The evolving crosstalk between co-stimulatory and co-inhibitory receptors: HVEM-BTLA. Trends Immunol 2005;26:292-294.
    • (2005) Trends Immunol , vol.26 , pp. 292-294
    • Croft, M.1
  • 51
    • 24944486256 scopus 로고    scopus 로고
    • Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway
    • Cheung TC, Humphreys IR, Potter KG, Norris PS, Shumway HM, Tran BR, et al. Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway. Proc Natl Acad Sci U S A 2005;102:13218-13223.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13218-13223
    • Cheung, T.C.1    Humphreys, I.R.2    Potter, K.G.3    Norris, P.S.4    Shumway, H.M.5    Tran, B.R.6
  • 52
    • 12844268068 scopus 로고    scopus 로고
    • A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator
    • Gonzalez LC, Loyet KM, Calemine-Fenaux J, Chauhan V, Wranik B, Ouyang W, et al. A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator. Proc Natl Acad Sci U S A 2005;102:1116-1121.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 1116-1121
    • Gonzalez, L.C.1    Loyet, K.M.2    Calemine-Fenaux, J.3    Chauhan, V.4    Wranik, B.5    Ouyang, W.6
  • 54
    • 20044389839 scopus 로고    scopus 로고
    • The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses
    • Wang Y, Subudhi SK, Anders RA, Lo J, Sun Y, Blink S, et al. The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses. J Clin Invest 2005; 115:711-717.
    • (2005) J Clin Invest , vol.115 , pp. 711-717
    • Wang, Y.1    Subudhi, S.K.2    Anders, R.A.3    Lo, J.4    Sun, Y.5    Blink, S.6
  • 55
    • 33646050660 scopus 로고    scopus 로고
    • Cutting edge: B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation
    • Deppong C, Juehne TI, Hurchla M, Friend LD, Shah DD, Rose CM, et al. Cutting edge: B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation. J Immunol 2004;176:3909-3913.
    • (2004) J Immunol , vol.176 , pp. 3909-3913
    • Deppong, C.1    Juehne, T.I.2    Hurchla, M.3    Friend, L.D.4    Shah, D.D.5    Rose, C.M.6
  • 56
    • 0037810670 scopus 로고    scopus 로고
    • Watanabe N, Gavrieli M, Sedy JR, Yang J, Fallarino F, Loftin SK, et al. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Na Immunol 2003; 4:670-679.
    • Watanabe N, Gavrieli M, Sedy JR, Yang J, Fallarino F, Loftin SK, et al. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Na Immunol 2003; 4:670-679.
  • 57
    • 27144557202 scopus 로고    scopus 로고
    • Differential effects of B and T lymphocyte attenuator and programmed death-1 on acceptance of partially versus fully MHC-mismatched cardiac allografts
    • Tao R, Wang L, Han R, Wang T, Ye Qi Honjo T, et al. Differential effects of B and T lymphocyte attenuator and programmed death-1 on acceptance of partially versus fully MHC-mismatched cardiac allografts. J Immunol 2005;175:5774-5782.
    • (2005) J Immunol , vol.175 , pp. 5774-5782
    • Tao, R.1    Wang, L.2    Han, R.3    Wang, T.4    Ye, Q.5    Honjo, T.6


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