Database of somatic mutations in EGFR with analyses revealing indel hotspots but no smoking-associated signature

Human Mutation

Volumn 28, Issue 8, 2007, Pages 760-770

  Gu, Dongqing ^a   Scaringe, William A ^a   Li, Kai ^a,b   Saldivar, Juan Sebastian ^a   Hill, Kathleen A ^a,c   Chen, Zhenbin ^a   Gonzalez, Kelly D ^a   Sommer, Steve S ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF SOUTH CHINA   (China)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

EGFR; Epidermal growth factor receptor; Erlotinib; Gefitinib; Mutation database; Non small cell lung cancer; Smoking; TKI; Tyrosine kinase inhibitor

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; PROTEIN TYROSINE KINASE INHIBITOR;

ARTICLE; DRUG MECHANISM; EXON; GENE DELETION; HUMAN; LUNG NON SMALL CELL CANCER; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SMOKING; SOMATIC MUTATION;

ADULT; AGED; BASE SEQUENCE; CLUSTER ANALYSIS; DATABASES, GENETIC; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, SECONDARY; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SEQUENCE DELETION; SMOKING;

EID: 34548052247     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.20512     Document Type: Article

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