Diversity of physiological cell reactivity to heat shock protein 60 in different mouse strains

Cell Stress and Chaperones

Volumn 12, Issue 2, 2007, Pages 112-122

  Luna, Ernesto ^a   Postol, Edilberto ^a   Caldas, Cristina ^a   Mundel, Luiz R ^a   Porto, Georgia ^a   Iwai, Leo K ^a   Ho, Paulo Lee ^c   Kalil, Jorge ^a,b   Coelho, Verônica ^a,b,d  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Institute for Investigation in Immunology INCT   (Brazil)

^c INSTITUTO BUTANTAN   (Brazil)

^d Instituto Coração   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HEAT SHOCK PROTEIN 60; INTERLEUKIN 10; ANTIGEN; CHAPERONIN; INTERLEUKIN 4; PEPTIDE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GRAFT REJECTION; IMMUNOTHERAPY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL; TH2 CELL; ANIMAL; BIOSYNTHESIS; C3H MOUSE; C57BL MOUSE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; HUMAN; MOLECULAR GENETICS; MOUSE STRAIN; SPLEEN;

MUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS; CELL PROLIFERATION; CHAPERONIN 60; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-4; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; PEPTIDES; SPLEEN;

EID: 34548036760     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1379/CSC-209R.1     Document Type: Article

References (47)

1. Ablamunits V, Elias D, Cohen IR. 1999. The pathogenicity of islet-infiltrating lymphocytes in the nonobese diabetic (NOD)mouse. Clin Exp Immunol 115: 260-267.
2. Abulafia-Lapid R, Elias D, Raz I, Keren-Zur Y, Atlan H, Cohen IR. 1999. T-cell proliferative responses of type 1 diabetes patients and healthy individuals to human Hsp60 and its peptides. J Autoimmun 12: 121-129.
3. Aida Y, Pabst MJ. 1990. Removal of endotoxin from protein solutions by phase separation using Triton X-114. J Immunol Methods 132: 191-195.
4. Birk OS, Elias D, Weiss AS, et al. 1996. NOD mouse diabetes: the ubiquitous mouse Hsp60 is a beta-cell target antigen of autoimmune T-cells. J Autoimmun 9: 159-166.
5. Birk OS, Gur SL, Elias D, et al. 1999. The 60-kDa heat shock protein modulates allograft rejection. Proc Natl Acad Sci U S A 96: 5159-5163.
6. Caldas C, Luna E, Spadafora-Ferreira M, et al. 2006. Cellular autoreactivity against heat shock protein 60 in renal transplant patients: peripheral and graft-infiltrating responses. Clin Exp Immunol 146: 66-75.
7. Chen W, Syldath U, Bellmann K, Burkart V, Kolb H. 1999. Human 60-kDa heat shock protein: a danger signal to the innate immune system. J Immunol 162: 3212-3219.
8. Cohen IR. 2002. Peptide therapy for type I diabetes: the immunological homunculus and the rationale for vaccination. Diabetologia 45: 1468-1474.
9. Cohen IR. 2004. Thoughts on the pathogenesis of type 1 diabetes and on the arrest of autoimmune beta-cell destruction by peptide p277 vaccination. Isr Med Assoc J 6: 260-261.
10. Cohen-Sfady M, Nussbaum G, Pevsner-Fischer M, Mor F, Carmi P, Zanin-Zhorov A, Lider O, Cohen IR. 2005. Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway. J Immunol 175: 3594-3602.
11. de Kleer IM, Kamphuis SM, Rijkers GT, et al. 2003. The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T-cells directed to human heat shock protein 60 capable of producing the regulatory cytokine interleukin-10. Arthritis Rheum 48: 2001-2010.
12. Durai MR, Gupta S, Moudgil KD. 2004. The T-cells specific for the carboxyl-terminal determinants of self (rat) heat shock protein 65 escape tolerance induction and are involved in regulation of autoimmune arthritis. J Immunol 172: 2795-2802.
13. Elias D, Cohen IR. 1994. Peptide therapy for diabetes in NOD mice. Lancet 343: 704-706.
14. Elias D, Markovits D, Reshef T, van der Zee R, Cohen IR. 1990. Induction and therapy of autoimmune diabetes in the nonobese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein. Proc Natl Acad Sci U S A 87: 1576-1580.
15. Elias D, Meilin A, Ablamunits V, et al. 1997. Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens. Diabetes 46: 758-764.
16. Flohe SB, Bruggemann J, Lendemans S, Nikulina M, Meierhoff G, Flohe S, Kolb H. 2003. Human heat shock protein 60 induces maturation of dendritic cells versus a Th1-promoting phenotype. J Immunol 170: 2340-2348.
17. Gao B, Tsan MF. 2004. Induction of cytokines by heat shock proteins and endotoxin in murine macrophages. Biochem Biophys Res Commun 317: 1149-1154.
18. Gaston JS, Life PF, Jenner PJ, Colston MJ, Bacon PA. 1990. Recognition of a mycobacteria-specific epitope in the 65-kD heat shock protein by synovial fluid-derived T-cell clones. J Exp Med 171: 831-841.
19. Habich C, Kempe K, van Der Zee R, et al. 2005. Heat shock protein 60: specific binding of lipopolysaccharide. J Immunol 17: 1298-1305.
20. Hightower LE, Guidon PT Jr. 1989. Selective release from cultured mammalian cells of heat shock (stress) proteins that resemble glia-axon transfer proteins. J Cell Physiol 138: 257-266.
21. Jones DB, Coulson AF, Duff GW. 1993. Sequence homologies between Hsp60 and autoantigens. Immunol Today 14: 115-118.
22. Kamphuis S, Kuis W, de Jager W, et al. 2005. Tolerogenic immune responses to novel T-cell epitopes from heat shock protein 60 in juvenile idiopathic arthritis. Lancet 366: 50-56.
23. Kaufmann SH. 1990. Heat shock proteins and the immune response. Immunol Today 11: 129-136.
24. Kilmartin B, Reen DJ. 2004. Hsp60 induces self-tolerance to repeated Hsp60 stimulation and crosstolerance to other proinflammatory stimuli. Eur J Immunol 34: 2041-2051.
25. Lehner T, Stanford MR, Phipps PA, et al. 2003. Immunopathogenesis and prevention of uveitis with the Behcet's disease-specific peptide linked to cholera toxin B. Adv Exp Med Biol 528: 173-180.
26. Lindquist S, Craig EA. 1988. The heat shock proteins. Annu Rev Genet 22: 631-677.
27. Maron R, Sukhova G, Faria AM, et al. 2002. Mucosal administration of heat shock protein 65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice. Circulation 106: 1708-1715.
28. Matzinger P. 1994. Tolerance, danger, and the extended family. Annu Rev Immunol 12: 991-1045.
29. Moliterno R, Valdivia L, Pan F, Duquesnoy RJ. 1995. Heat shock protein reactivity of lymphocytes isolated from heterotopic rat cardiac allografts. Transplantation 59: 598-604.
30. Moudgil KD, Chang TT, Eradat H, et al. 1997. Diversification of T-cell responses to carboxy-terminal determinants within the 65-kD heat shock protein is involved in regulation of autoimmune arthritis. J Exp Med 185: 1307-1316.
31. Ohashi K, Burkart V, Flohe S, Kolb H. 2000. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 164: 558-561.
32. Paul AG, van Der Zee R, Tams LS, van Eden W. 2000. A self-Hsp60 peptide acts as a partial agonist inducing expression of B7-2 on mycobacterial Hsp60-specific T-cells: a possible mechanism for inhibitory T-cell regulation of adjuvant arthritis? Int Immunol 12: 1041-1050.
33. Paul AG, van Kooten PJ, van Eden W, van Der Zee R. 2000. Highly autoproliferative T-cells specific for 60-kDa heat shock protein produce IL-4/IL-10 and IFN-gamma and are protective in adjuvant arthritis. J Immunol 165: 7270-7277.
34. Pockley AG, Muthana M. 2005. Heat shock proteins and allograft rejection. Contrib Nephrol 148: 122-134.
35. Prohaszka Z, Fust G. 2004. Immunological aspects of heat shock proteins - the optimum stress of life. Mol Immunol 41: 29-44.
36. Puga Yung GL, Le TD, Roord S, Prakken B, Albani S. 2003. Heat shock proteins (Hsp) for immunotherapy of rheumatoid arthritis (RA). Inflamm Res 52: 443-451.
37. Quintana FJ, Carmi P, Mor F, Cohen IR. 2003. DNA fragments of the human 60-kDa heat shock protein (Hsp60) vaccinate against adjuvant arthritis: identification of a regulatory Hsp60 peptide. J Immunol 171: 3533-3541.
38. Raz I, Elias D, Avron A, Tamir M, Metzer M, Cohen IR. 2001. Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat shock protein peptide (DiaPep277): a randomized, double-blind, phase II trial. Lancet 358: 1749-1753.
39. Stanford M, Whittall T, Bregmeier LA, et al. 2004. Oral tolerization with peptide 336-351 linked to cholera toxin B subunit in preventing relapses of uveitis in Behcet's disease. Clin Exp Immunol 137: 201-208.
40. van Eden W. 2006. Immunoregulation of autoimmune diseases. Hum Immunol 67: 446-453.
41. van Eden W, Hauet-Broere F, Berlo S, et al. 2005a. Stress proteins as inducers and targets of regulatory T-cells in arthritis. Int Rev Immunol 24: 181-197.
42. van Eden W, Thole JE, van Der Zee R, et al. 1988. Cloning of the mycobacterial epitope recognized by T-lymphocytes in adjuvant arthritis. Nature 331: 171-173.
43. van Eden W, van der Zee R, Prakken B. 2005b. Heat shock proteins induce T-cell regulation of chronic inflammation. Nat Rev Immunol 5: 318-330.
44. van Roon JA, van Eden W, van Roy JL, Lafeber FJ, Bijlsma JW. 1997. Stimulation of suppressive T-cell responses by human but not bacterial 60-kD heat shock protein in synovial fluid of patients with rheumatoid arthritis. J Clin Invest 100: 459-463.
45. Wellings DA, Atherton E. 1997. Standard Fmoc protocols. Methods Enzymol 289: 44-67.
46. Zanin-Zhorov A, Bruck R, Tal G, et al. 2005. Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines. J Immunol 174: 3227-3336.
47. Zanin-Zhorov A, Nussbaum G, Franitza S, Cohen IR, Lider O. 2003. T-cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors. Faseb J 17: 1567-1569.