Adenosine stimulates the basolateral 50 pS K channels in the thick ascending limb of the rat kidney

American Journal of Physiology - Renal Physiology

Volumn 293, Issue 1, 2007, Pages

  Gu, Ruimin ^a   Wang, Jing ^a   Zhang, Yunhong ^a   Li, Wennan ^a   Xu, Ying ^a   Shan, Hongli ^a   Wang, Wen Hui ^b   Yang, Baofeng ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Adenosine receptor; Epithelial transport; Protein kinase A; Renal K channel

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 8 (3 CHLOROSTYRYL)CAFFEINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; CYCLIC AMP DEPENDENT PROTEIN KINASE; POTASSIUM CHANNEL; 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE; 8-(3-CHLOROSTYRYL)CAFFEINE; ADENOSINE A2 RECEPTOR; ADENYLATE CYCLASE; BUCLADESINE; CAFFEINE; DRUG DERIVATIVE; N(6) CYCLOHEXYLADENOSINE; N(6)-CYCLOHEXYLADENOSINE; PHENETHYLAMINE DERIVATIVE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; FEMALE; HYPERPOLARIZATION; KIDNEY; MALE; MEMBRANE PERMEABILITY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; ALGORITHM; ANIMAL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; METABOLISM; SPRAGUE DAWLEY RAT; STIMULATION;

ADENOSINE; ADENYLATE CYCLASE; ALGORITHMS; ANIMALS; BUCLADESINE; CAFFEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; KIDNEY; MALE; PATCH-CLAMP TECHNIQUES; PHENETHYLAMINES; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADENOSINE A2; STIMULATION, CHEMICAL; XANTHINES;

EID: 34548034458     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00008.2007     Document Type: Article

References (30)

1. Burnatowska-Hledin MA, Spielman WS. Effects of adenosine on cAMP production and cytosolic Ca in cultured rabbit medullary thick ascending limb cells. Am J Physiol Cell Physiol 260: C143-C150, 1991.
2. Cheng MK, Doumad AB, Jiang H, Falck JR, McGiff JC, Carroll MA. Epoxyeicosatrienoic acids mediate adenosine-induced vasodilation in rat preglomerular microvessels via A2a receptor. Br J Pharmacol 141: 441-448, 2004.
3. Conde SV, Obeso A, Vicario I, Rigual R, Rocher A, Conzalez C. Caffeine inhibition of rat carratid body chemoreceptors is mediated by A2A and A2B adenosine receptors. J Neurochem 98: 616-628, 2006.
4. Feoktistov I, Biaggioni I. Pharmacological characterization of adenosine A2B receptors studies in human mast cells co-expressing A2A and A2B adenosine receptor subtypes. Biochem Pharmacol 55: 627-633, 1998.
5. Fiebich BL, Biber K, Gyufko K, Berger M, Bauer J, van Calker D. Adenosine A2b receptors mediate an increase in interleukin (IL)-6 mRNA and IL-6 protein synthesis in human astroglioma cells. J Neurochem 66: 1426-1431, 1996.
6. Giebisch G. Renal potassium transport:mechanisms and regulation. Am J Physiol Renal Physiol 274: F817-F833, 1998.
7. Greger R. Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron. Physiol Rev 65: 760-797, 1985.
8. Gu RM, Wang WH. Arachidonic acid inhibits K channels in basolateral membrane of the thick ascending limb. Am J Physiol Renal Physiol 283: F407-F414, 2002.
9. Hansen PB, Schnermann J. Vasoconstrictor and vasodilator effects of adenosine in the kidney. Am J Physiol Renal Physiol 285: F590-F599, 2003.
10. Hebert SC. Roles of Na-K-2Cl and Na-Cl cotransporters and ROMK potassium channels in urinary concentrating mechanism. Am J Physiol Renal Physiol 275: F325-F327, 1998.
11. Hebert SC, Desir G, Giebisch G, Wang W. Molecular diversity and regulation of renal potassium channels. Physiol Rev 85: 319-371, 2005.
12. Jackson EK, Dubey RK. Role of the extracellular cAMP-adenosine pathway in renal physiology. Am J Physiol Renal Physiol 281: F597-F612, 2001.
13. Jacobson KA, Nikodijevic O, Padgett WL, Gallo-Rodriguez C, Maillard M, Daly JW. 8-(3-Chlorostyryl)caffeine (CSC) is a selective A2-adenosine antagonist in vitro and in vivo. FEBS Lett 323: 141-144, 1993.
14. Kim SM, Mizel D, Huang YG, Briggs JP, Schnermann J. Adenosine as a mediator of macula densa-dependent inhibition of renin secretion. Am J Physiol Renal Physiol 290: F1016-F1023, 2006.
15. Li D, Wei Y, Wang WH. Dietary K intake regulates the response of apical K channels to adenosine in the thick ascending limb. Am J Physiol Renal Physiol 287: F954-F959, 2004.
16. Macala LJ, Hayslett JP. Basolateral and apical A1 adenosine receptors mediate sodium transport in cultured renal epithelial (A6) cells. Am J Physiol Renal Physiol 283: F1216-F1225, 2002.
17. Munger KA, Jackson EK. Effects of selective A1 receptor blockade on glomerular hemodynamics: involvement of renin-angiotensin system. Am J Physiol Renal Fluid Electrolyte Physiol 267: F783-F790, 1994.
18. Okusa MD. A2A adenosine receptor: a novel therapeutic target in renal disease. Am J Physiol Renal Physiol 282: F10-F18, 2002.
19. Paulais M, Lourdel S, Teulon J. Properties of an inwardly rectifying K channel in the basolateral membrane of mouse TAL. Am J Physiol Renal Physiol 282: F866-F876, 2002.
20. Schnermann J, Levine DZ. Paracrine factor in tubuloglomerular feedback: adenosine, ATP, and nitric oxide. Annu Rev Physiol 65: 501-529, 2003.
21. Schulte G, Fredholm BB. Signalling from adenosine receptors to mitogen-activated protein kinases. Cell Signal 15: 813-827, 2003.
22. + channel, ROMK. Nat Genet 14: 152-156, 1996.
23. Siragy HM, Linden J. Sodium intake markedly alters renal interstitial fluid adenosine. Hypertension 27: 404-407, 1996.
24. Sole FD, Cerull R, Babich V, Quinones H, Gisler SM, Biber J, Murer H, Burckhardt G, Helmle-Kolb C, Woe OS. Acute regulation of NaH exchanger NHE3 by adenosine A1 receptor is mediated by calcineurin homologous protein. J Biol Chem 279: 2962-2974, 2004.
25. Spielman WS, Arend LJ. Adenosine receptors and signalin in the kidney. Hypertension 17: 117-130, 1991.
26. Sun P, Lin DH, Wang T, Babilonia E, Wang ZJ, Jin Y, Kemp R, Nasjletti A, Wang WH. Low Na intake suppresses the expression of CYP2C23 and the arachidonic acid-induced inhibition of ENaC. Am J Physiol Renal Physiol 291: F1192-F1200, 2006.
27. 3- cotransport in rabbit proximal convoluted tubule via adenosine A1 receptor. Am J Physiol Renal Fluid Electrolyte Physiol 265: F511-F519, 1993.
28. Vitzthum H, Weiss B, Bachleitner W, Krämer BK, Kurtz A. Gene expression of adenosine receptors along the nephron. Kidney Int 65: 1180-1190, 2004.
29. Wei Y, Sun P, Wang ZJ, Yang BF, Wang WH. Adenosine inhibits epithelial Na channels (ENaC) by cytochrome-P450 (CYP)- epoxygenasedependent metabolites of arachidonic acid. Am J Physiol Renal Physiol 290: F1163-F1168, 2006.
30. Yamaguchi S, Umemura S, Tamura K, Iwamoto T, Nyui N, Ishgami T, Ishii M. Adenosine A1 receptor mRNA in microdissected rat nephron segments. Hypertension 26: 1181-1185, 1995.