Requirement of the tumour suppressor APC for the clustering of PSD-95 and AMPA receptors in hippocampal neurons

European Journal of Neuroscience

Volumn 26, Issue 4, 2007, Pages 903-912

  Shimomura, Atsushi ^a,b   Ohkuma, Mahito ^a   Iizuka Kogo, Akiko ^a   Kohu, Kazuyoshi ^c,d   Nomura, Ryuji ^a   Miyachi, Ei Ichi ^a   Akiyama, Tetsu ^c   Senda, Takao ^a  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOHOKU UNIVERSITY   (Japan)

Author keywords

Glutamatergic synapse; NMDA receptor

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; APC PROTEIN; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POSTSYNAPTIC DENSITY PROTEIN 95; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; FEMALE; GENE CLUSTER; GENE CONSTRUCT; GENE EXPRESSION; GENE INTERACTION; GENE OVEREXPRESSION; HIPPOCAMPUS; HUMAN; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTOGENESIS; TUMOR SUPPRESSOR GENE;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; BLOTTING, WESTERN; CERCOPITHECUS AETHIOPS; CLUSTER ANALYSIS; COS CELLS; EXCITATORY AMINO ACID AGONISTS; FLUORESCENT DYES; FURA-2; GENES, APC; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE; NERVE TISSUE PROTEINS; PLASMIDS; RECEPTORS, AMPA; RNA, SMALL INTERFERING; SYNAPSES; TRANSFECTION;

EID: 34547977405     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05723.x     Document Type: Article

References (32)

1. Bhat, R.V., Baraban, J.M., Johnson, R.C., Eipper, B.A. Mains, R.E. (1994) High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system. J. Neurosci., 14, 3059 3071.
2. Bredt, D.S. Nicoll, R.A. (2003) AMPA receptor trafficking at excitatory synapses Neuron, 40, pp. 361 379.
3. Brenman, J.E., Chao, D.S., Gee, S.H., McGee, A.W., Craven, S.E., Santillano, D.R., Wu, Z., Huang, F., Xia, H., Peters, M.F., Froehner, S.C. Bredt, D.S. (1996) Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains. Cell, 84, 757 767.
4. Cai, C., Li, H., Rivera, C. Keinanen, K. (2006) Interaction between SAP97 and PSD-95, two Maguk proteins involved in synaptic trafficking of AMPA receptors. J. Biol. Chem., 281, 4267 4273.
5. Colledge, M., Snyder, E.M., Crozier, R.A., Soderling, J.A., Jin, Y., Langeberg, L.K., Lu, H., Bear, M.F. Scott, J.D. (2003) Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron, 40, 595 607.
6. Craven, S.E., El-Husseini, A.E. Bredt, D.S. (1999) Synaptic targeting of the postsynaptic density protein PSD-95 mediated by lipid and protein motifs. Neuron, 22, 497 509.
7. Dobashi, Y., Katayama, K., Kawai, M., Akiyama, T. Kameya, T. (2000) APC protein is required for initiation of neuronal differentiation in rat pheochromocytoma PC12 cells. Biochem. Biophys. Res. Commun., 279, 685 691.
8. El-Husseini Ael, D., Schnell, E., Dakoji, S., Sweeney, N., Zhou, Q., Prange, O., Gauthier-Campbell, C., Aguilera-Moreno, A., Nicoll, R.A. Bredt, D.S. (2002) Synaptic strength regulated by palmitate cycling on PSD-95. Cell, 108, 849 863.
9. El-Husseini, A.E., Schnell, E., Chetkovich, D.M., Nicoll, R.A. Bredt, D.S. (2000) PSD-95 involvement in maturation of excitatory synapses. Science, 290, 1364 1368.
10. Groden, J., Thliveris, A., Samowitz, W., Carlson, M., Gelbert, L., Albertsen, H., Joslyn, G., Stevens, J., Spirio, L., Robertson, M., Sargeant, L., Krapcho, K., Wolff, E., Burt, R., Hughes, J.P., Warrington, J., McPherson, J., Wasmuth, J., Le Paslier, D., Abderrahim, H., Cohen, D., Leppert, M. White, R. (1991) Identification and characterization of the familial adenomatous polyposis coli gene. Cell, 66, 589 600.
11. Jimbo, T., Kawasaki, Y., Koyama, R., Sato, R., Takada, S., Haraguchi, K. Akiyama, T. (2002) Identification of a link between the tumour suppressor APC and the kinesin superfamily. Nature Cell Biol., 4, 323 327.
12. Kim, E., Niethammer, M., Rothschild, A., Jan, Y.N. Sheng, M. (1995) Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases. Nature, 378, 85 88.
13. Kim, E. Sheng, M. (2004) PDZ domain proteins of synapses. Nature Rev. Neurosci., 5, 771 781.
14. Kinzler, K.W., Nilbert, M.C., Su, L.K., Vogelstein, B., Bryan, T.M., Levy, D.B., Smith, K.J., Preisinger, A.C., Hedge, P., McKechnie, D., Finniear, R., Markham, A., Groffen, J., Boguski, M.S., Altschul, S.F., Horii, A., Ando, H., Miyoshi, Y., Miki, Y., Nishisho, I. Nakamura, Y. (1991) Identification of FAP locus genes from chromosome 5q21. Science, 253, 661 665.
15. Kornau, H.C., Schenker, L.T., Kennedy, M.B. Seeburg, P.H. (1995) Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science, 269, 1737 1740.
16. Leonard, A.S., Davare, M.A., Horne, M.C., Garner, C.C. Hell, J.W. (1998) SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit. J. Biol. Chem., 273, 19518 19524.
17. Li, Z. Sheng, M. (2003) Some assembly required: the development of neuronal synapses. Nature Rev. Mol. Cell Biol., 4, 833 841.
18. Munemitsu, S., Souza, B., Muller, O., Albert, I., Rubinfeld, B. Polakis, P. (1994) The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res., 54, 3676 3681.
19. Nishisho, I., Nakamura, Y., Miyoshi, Y., Miki, Y., Ando, H., Horii, A., Koyama, K., Utsunomiya, J., Baba, S. Hedge, P. (1991) Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science, 253, 665 669.
20. Ohkuma, M., Kawai, F. Miyachi, E. (2002) Direct suppression by odorants of ionotropic glutamate receptors in newt retinal neurons. J. Neural Transm., 109, 1365 1371.
21. Palay, S.L. (1958) The morphology of synapses in the central nervous system. Exp. Cell Res., 14, 275 293.
22. Powell, S.M., Zilz, N., Beazer-Barclay, Y., Bryan, T.M., Hamilton, S.R., Thibodeau, S.N., Vogelstein, B. Kinzler, K.W. (1992) APC mutations occur early during colorectal tumorigenesis. Nature, 359, 235 237.
23. Rao, A., Kim, E., Sheng, M. Craig, A.M. (1998) Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture. J. Neurosci., 18, 1217 1229.
24. Senda, T., Iino, S., Matsushita, K., Matsumine, A., Kobayashi, S. Akiyama, T. (1998) Localization of the adenomatous polyposis coli tumour suppressor protein in the mouse central nervous system. Neuroscience, 83, 857 866.
25. Shimomura, A., Kohu, K., Akiyama, T. Senda, T. (2005) Subcellular localization of the tumor suppressor protein APC in developing cultured neurons. Neurosci. Lett., 375, 81 86.
26. Takamori, N., Shimomura, A. Senda, T. (2006) Microtubule-bundling activity of APC is stimulated by interaction with PSD-95. Neurosci. Lett., 403, 68 72.
27. Temburni, M.K., Rosenberg, M.M., Pathak, N., McConnell, R. Jacob, M.H. (2004) Neuronal nicotinic synapse assembly requires the adenomatous polyposis coli tumor suppressor protein. J. Neurosci., 24, 6776 6784.
28. Votin, V., Nelson, W.J. Barth, A.I. (2005) Neurite outgrowth involves adenomatous polyposis coli protein and beta-catenin. J. Cell Sci., 118, 5699 5708.
29. Wang, J., Jing, Z., Zhang, L., Zhou, G., Braun, J., Yao, Y. Wang, Z.Z. (2003) Regulation of acetylcholine receptor clustering by the tumor suppressor APC. Nature Neurosci., 6, 1017 1018.
30. Yanai, H., Satoh, K., Matsumine, A. Akiyama, T. (2000) The colorectal tumour suppressor APC is present in the NMDA-receptor-PSD-95 complex in the brain. Genes Cells, 5, 815 822.
31. Zhou, F.Q., Zhou, J., Dedhar, S., Wu, Y.H. Snider, W.D. (2004) NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC. Neuron, 42, 897 912.
32. Zumbrunn, J., Kinoshita, K., Hyman, A.A. Nathke, I.S. (2001) Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr. Biol., 11, 44 49.