Time course effects of adrenalectomy and food intake on cocaine- and amphetamine-regulated transcript expression in the hypothalamus

Brain Research

Volumn 1166, Issue 1, 2007, Pages 55-64

  Germano, Carla M R ^a,b   de Castro, Margaret ^a   Rorato, Rodrigo ^a   Laguna, Maria Teresa C ^a   Antunes Rodrigues, Jose ^a   Elias, Carol F ^a   Elias, Lucila L K ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

Author keywords

Adrenalectomy; CART; Food intake; In situ hybridization; Leptin

Indexed keywords

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; CORTICOSTERONE; CORTICOTROPIN; LEPTIN;

ADRENALECTOMY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BODY WEIGHT; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; FOOD INTAKE; GENE EXPRESSION; HORMONE RELEASE; HYPOTHALAMUS; IN SITU HYBRIDIZATION; ISOTOPE LABELING; MALE; MICROSCOPE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; THALAMUS MIDLINE NUCLEUS;

ADIPOSITY; ADRENAL GLANDS; ADRENALECTOMY; ADRENOCORTICOTROPIC HORMONE; ANIMALS; CORTICOSTERONE; EATING; ENERGY METABOLISM; FEEDING BEHAVIOR; GLUCOCORTICOIDS; HYPOTHALAMUS; LEPTIN; MALE; NERVE TISSUE PROTEINS; RATS; RATS, WISTAR; RNA, MESSENGER; TIME FACTORS;

RATTUS; RATTUS NORVEGICUS;

EID: 34547954723     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.05.077     Document Type: Article

References (58)

1. Ahima R.S., Kelly J., Elmquist J.K., and Flier J.S. Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia. Endocrinology 140 (1999) 4923-4931
2. Balkan B., Koylu E.O., Kuhar M.J., and Pogun S. The effect of adrenalectomy on cocaine and amphetamine-regulated transcript (CART) expression in the hypothalamic nuclei of the rat. Brain Res. 917 (2001) 15-20
3. Balkan B., Koylu E., Pogun S., and Kuhar M.J. Effects of adrenalectomy on CART expression in the rat arcuate nucleus. Synapse 50 (2003) 14-19
4. Banks W.A., Kastin A.J., Huang W., Jaspan J.B., and Maness L.M. Leptin enters the brain by a saturable system independent of insulin. Peptides 17 (1996) 305-311
5. Bruce B.K., King B.M., Phelps G.R., and Veitia M.C. Effects of adrenalectomy and corticosterone administration on hypothalamic obesity in rats. Am. J. Physiol. 243 (1982) E152-E157
6. Castro M., Figueiredo F., and Moreira A.C. Time course of hypothalamic CRH and pituitary ACTH contents, and pituitary responsiveness to CRH stimulation after bilateral adrenalectomy. Horm. Metab. Res. 27 (1995) 10-15
7. Couceyro P.R., Koylu E.O., and Kuhar M.J. Further studies on the anatomical distribution of CART by in situ hybridization. J. Chem. Neuroanat. 12 (1997) 229-241
8. Dallman M.F., Strack A.M., Akana S.F., Bradbury M.J., Hanson E.S., Scribner K.A., and Smith M. Feast and famine: critical role of glucocorticoids with insulin in daily energy flow. Front. Neuroendocrinol. 14 (1993) 303-347
9. Denis R.G., Williams G., and Vernon R.G. Regulation of serum leptin and its role in the hyperphagia of lactation in the rat. J. Endocrinol. 176 (2003) 193-203
10. De Kloet E.R., Vreugdenhil E., Oitzl M.S., and Joels M. Brain corticosteroid receptor balance in health and disease. Endocr. Rev. 19 (1998) 269-301
11. Douglass J., McKinzie A.A., and Couceyro P. PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine. J. Neurosci. 15 (1995) 2471-2481
12. Elias C.F., Lee C., Kelly J., Aschkenasi C., Ahima R.S., Couceyro P.R., Kuhar M.J., Saper C.B., and Elmquist J.K. Leptin activates hypothalamic CART neurons projecting to the spinal cord. Neuron 21 (1998) 1375-1385
13. Elias C.F., Kelly J.F., Lee C.E., Ahima R.S., Drucker D.J., Saper C.B., and Elmquist J.K. Chemical characterization of leptin-activated neurons in the rat brain. J. Comp. Neurol. 423 (2000) 261-281
14. Elias C.F., Lee C.E., Kelly J.F., Ahima R.S., Kuhar M., Saper C.B., and Elmquist J.K. Characterization of CART neurons in the rat and human hypothalamus. J. Comp. Neurol. 432 (2001) 1-19
15. Elias L.L., Campos A.D., and Moreira A.C. The opposite effects of short- and long-term salt loading on pituitary adrenal axis activity in rats. Horm. Metab. Res. 34 (2002) 207-211
16. Elmquist J.K., Bjorbaek C., Ahima R.S., Flier J.S., and Saper C.B. Distributions of leptin receptor mRNA isoforms in the rat brain. J. Comp. Neurol. 395 (1998) 535-547
17. Elmquist J.K., Maratos-Flier E., Saper C.B., and Flier J.S. Unraveling the central nervous system pathways underlying responses to leptin. Nat. Neurosci. 1 (1998) 445-450
18. Elmquist J.K., Elias C.F., and Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22 (1999) 221-232
19. Fulton S., Richard D., Woodside B., and Shizgal P. Interaction of CRH and energy balance in the modulation of brain stimulation reward. Behav. Neurosci. 116 (2002) 651-659
20. Gautvik K.M., de Lecea L., Gautvik V.T., Danielson P.E., Tranque P., Dopazo A., Bloom F.E., and Sutcliffe J.G. Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 8733-8738
21. Guillemin R. Hypothalamic hormones a.k.a. hypothalamic releasing factors. J. Endocrinol. 184 (2005) 11-28
22. Hillhouse E.W., and Jones M.T. Effect of bilateral adrenalectomy and corticosteroid therapy on the secretion of corticotrophin-releasing factor activity from the hypothalamus of the rat in vitro. J. Endocrinol. 71 (1976) 21-30
23. Hillhouse E.W., and Grammatopoulos D.K. The molecular mechanisms underlying the regulation of the biological activity of corticotropin-releasing hormone receptors: implications for physiology and pathophysiology. Endocr. Rev. 27 (2006) 260-286
24. Keller P.A., Compan V., Bockaert J., Giacobino J.P., Charnay Y., Bouras C., and Assimacopoulos-Jeannet F. Characterization and localization of cocaine- and amphetamine-regulated transcript (CART) binding sites. Peptides 27 (2006) 1328-1334
25. Koylu E.O., Couceyro P.R., Lambert P.D., Ling N.C., DeSouza E.B., and Kuhar M.J. Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland. J. Neuroendocrinol. 9 (1997) 823-833
26. Koylu E.O., Couceyro P.R., Lambert P.D., and Kuhar M.J. Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain. J. Comp. Neurol. 391 (1998) 115-132
27. Kristensen P., Judge M.E., Thim L., Ribel U., Christjansen K.N., Wulff B.S., Clausen J.T., Jensen P.B., Madsen O.D., Vrang N., Larsen P.J., and Hastrup S. Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393 (1998) 72-76
28. Laferrere B., Abraham C., Awad M., Jean-Baptiste S., Hart A.B., Garcia-Lorda P., Kokkoris P., and Russell C.D. Inhibiting endogenous cortisol blunts the meal-entrained rise in serum leptin. J. Clin. Endocrinol. Metab. 91 (2006) 2232-2238
29. Larsen P.J., Vrang N., Petersen P.C., Kristensen P., Rohner-Jeanrenaud F., Craft L.S., Bridwell J., Suter T.M., Tinsley F.C., Smiley D.L., Burkhart D.R., Statnick M.A., Heiman M.L., Ravussin E., and Caro J.F. Chronic intracerebroventricular administration of recombinant CART(42-89) peptide inhibits and causes weight loss in lean and obese Zucker (fa/fa) rats. Obes. Res. 8 (2000) 590-596
30. Larsen P.J., Seier V., Fink-Jensen A., Holst J.J., Warberg J., and Vrang N.J. Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit. J. Neuroendocrinol. 15 (2003) 219-226
31. Leibowitz S.F., and Wortley K.E. Hypothalamic control of energy balance: different peptides, different functions. Peptides 25 (2004) 473-504
32. Marks D.L., Wiemann J.N., Burton K.A., Lent K.L., Clifton D.K., and Steiner R.A. Simultaneous visualization of two cellular mRNA species in individual neurons by use of a new double in situ hybridization method. Mol. Cell. Neurosci. 3 (1992) 395-405
33. McAlister E.D., and Van Vugt D.A. Effect of leptin administration versus re-feeding on hypothalamic neuropeptide gene expression in fasted male rats. Can. J. Physiol. Pharmacol. 82 (2004) 1128-1134
34. Murphy K.G., Abbott C.R., Mahmoudi M., Hunter R., Gardiner J.V., Rossi M., Stanley S.A., Ghatei M.A., Kuhar M.J., and Bloom S.R. Quantification and synthesis of cocaine- and amphetamine-regulated transcript peptide (79-102)-like immunoreactivity and mRNA in rat tissues. J. Endocrinol. 166 (2000) 659-668
35. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1998), Academic Press, Sydney
36. Peters J.H., McKay B.M., Simasko S.M., and Ritter R.C. Leptin-induced satiation mediated by abdominal vagal afferents. Am. J. Physiol.: Regul. Integr. Comp. Physiol. 288 (2005) R879-R884
37. Rohner-Jeanrenaud F., Craft L.S., Bridwell J., Suter T.M., Tinsley F.C., Smiley D.L., Burkhart D.R., Statnick M.A., Heiman M.L., Ravussin E., and Caro J.F. Chronic central infusion of cocaine- and amphetamine-regulated transcript (CART 55-102): effects on body weight homeostasis in lean and high-fat-fed obese rats. Int. J. Obes. Relat. Metab. Disord. 26 (2002) 143-149
38. Saladin R., De Vos P., Guerre-Millo M., Leturque A., Girard J., Staels B., and Auwerx J. Transient increase in obese gene expression after food intake or insulin administration. Nature 377 (1995) 527-529
39. Saper C.B., Chou T.C., and Elmquist J.K. The need to feed: homeostatic and hedonic control of eating. Neuron 36 (2002) 199-211
40. Savontaus E., Conwell I.M., and Wardlaw S.L. Effects of adrenalectomy on AGRP, POMC, NPY and CART gene expression in the basal hypothalamus of fed and fasted rats. Brain Res. 958 (2002) 130-138
41. Scarpace P.J., Nicolson M., and Matheny M. JUCP2, UCP3 and leptin gene expression: modulation by food restriction and leptin. J. Endocrinol. 159 (1998) 349-357
42. Schwartz M.W., Woods S.C., Porte Jr. D., Seeley R.J., and Baskin D.G. Central nervous system control of food intake. Nature 404 (2000) 661-671
43. Simmons D.M., Arriza J.L., and Swanson L.W. A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabelled single stranded RNA probes. J. Histotechnol. 12 (1989) 169-181
44. Stanley S.A., Small C.J., Murphy K.G., Rayes E., Abbott C.R., Seal L.J., Morgan D.G., Sunter D., Dakin C.L., Kim M.S., Hunter R., Kuhar M., Ghatei M.A., and Bloom S.R. Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats. Brain Res. 893 (2001) 186-194
45. Tempel D.L., and Leibowitz S.F. Glucocorticoid receptors in PVN: interactions with NE, NPY, and Gal in relation to feeding. Am. J. Physiol. 265 (1993) E794-E800
46. Trayhurn P., Thomas M.E., Duncan J.S., and Rayner D.V. Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (ob/ob) mice. FEBS Lett. 368 (1995) 488-490
47. Vicentic A., Dominguez G., Hunter R.G., Philpot K., Wilson M., and Kuhar M.J. Cocaine- and amphetamine-regulated transcript peptide levels in blood exhibit a diurnal rhythm: regulation by glucocorticoids. Endocrinology 145 (2004) 4119-4124
48. Vrang N., Larsen P.J., Clausen J.T., and Kristensen P. Neurochemical characterization of hypothalamic cocaine-amphetamine-regulated transcript neurons. J. Neurosci. 19 (1999) RC5
49. Vrang N., Larsen P.J., Kristensen P., and Tang-Christensen M. Central administration of cocaine-amphetamine-regulated transcript activates hypothalamic neuroendocrine neurons in the rat. Endocrinology 141 (2000) 794-801
50. Vrang N., Larsen P.J., Tang-Christensen M., Larsen L.K., and Kristensen P. Hypothalamic cocaine-amphetamine regulated transcript (CART) is regulated by glucocorticoids. Brain Res. 965 (2003) 45-50
51. Wabitsch M., Jensen P.B., Blum W.F., Christoffersen C.T., Englaro P., Heinze E., Rascher W., Teller W., Tornqvist H., and Hauner H. Insulin and cortisol promote leptin production in cultured human fat cells. Diabetes 45 (1996) 1435-1438
52. Wierup N., Richards W.G., Bannon A.W., Kuhar M.J., Ahren B., and Sundler F. CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight. Regul. Pept. 129 (2005) 203-211
53. Wynne K., Stanley S., McGowan B., and Bloom S. Appetite control. J. Endocrinol. 184 (2005) 291-318
54. Wittmann G., Liposits Z., Lechan R.M., and Fekete C. Origin of cocaine- and amphetamine-regulated transcript-containing axons innervating hypophysiotropic corticotropin-releasing hormone-synthesizing neurons in the rat. Endocrinology 146 (2005) 2985-2991
55. Yilmaz A., Suleyman H., Umudum Z., and Sahin Y.N. The effect of adrenalectomy on leptin levels and some metabolic parameters in rats with diet-induced obesity. Biol. Pharm. Bull. 25 (2002) 580-583
56. Yukimura Y., and Bray G.A. Effects of adrenalectomy on body weight and the size and number of fat cells in the Zucker (fatty) rat. Endocr. Res. Commun. 5 (1978) 189-198
57. Zakrzewska K.E., Sainsbury A., Cusin I., Rouru J., Jeanrenaud B., and Rohner-Jeanrenaud F. Selective dependence of intracerebroventricular neuropeptide Y-elicited effects on central glucocorticoids. Endocrinology 140 (1999) 3183-3187
58. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., and Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature 372 (1994) 425-432