Origin of cocaine- and amphetamine-regulated transcript-containing axons innervating hypophysiotropic corticotropin-releasing hormone-synthesizing neurons in the rat

Endocrinology

Volumn 146, Issue 7, 2005, Pages 2985-2991

  Wittmann, Gábor ^a   Liposits, Zsolt ^a   Lechan, Ronald M ^b,c   Fekete, Csaba ^a,b  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b TUFTS MEDICAL CENTER   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; AMPHETAMINE; COCAINE; CORTICOTROPIN RELEASING FACTOR; PHENYLETHANOLAMINE N METHYLTRANSFERASE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ALPHA INTERMEDIN; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; METHYLTRANSFERASE; NERVE PROTEIN; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; NERVE CELL; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; RAT; THALAMUS MIDLINE NUCLEUS; VARICOSIS; ANIMAL; ARCUATE NUCLEUS; BIOSYNTHESIS; CONFOCAL MICROSCOPY; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MEDULLA OBLONGATA; METABOLISM; PHYSIOLOGY; SYNAPTOSOME; TISSUE DISTRIBUTION; WISTAR RAT;

ALPHA-MSH; ANIMALS; ARCUATE NUCLEUS; AXONS; CORTICOTROPIN-RELEASING HORMONE; FLUORESCENT ANTIBODY TECHNIQUE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MEDULLA OBLONGATA; METHYLTRANSFERASES; MICROSCOPY, CONFOCAL; NERVE TISSUE PROTEINS; NEURONS; NEUROTRANSMITTER AGENTS; PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE; PITUITARY-ADRENAL SYSTEM; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 22144437390     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2005-0178     Document Type: Article

References (44)

1. Vale W, Spiess J, Rivier C, Rivier J 1981 Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and β-endorphin. Science 213:1394-1397
2. Lennard DE, Eckert WA, Merchenthaler I 1993 Corticotropin-releasing hormone neurons in the paraventricular nucleus project to the external zone of the median eminence: a study combining retrograde labeling with immunocytochemistry. J Neuroendocrinol 5:175-181
3. Koylu EO, Couceyro PR, Lambert PD, Ling NC, DeSouza EB, Kuhar MJ 1997 Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland. J Neuroendocrinol 9:823-833
4. Koylu EO, Couceyro PR, Lambert PD, Kuhar MJ 1998 Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain. J Comp Neurol 391:115-132
5. Fekete C, Mihaly E, Luo LG, Kelly J, Clausen JT, Mao Q, Rand WM, Moss LG, Kuhar M, Emerson CH, Jackson IM, Lechan RM 2000 Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting. J Neurosci 20:9224-9234
6. Vrang N, Larsen PJ, Kristensen P, Tang-Christensen M 2000 Central administration of cocaine-amphetamine-regulated transcript activates hypothalamic neuroendocrine neurons in the rat. Endocrinology 141:794-801
7. Smith SM, Vaughan JM, Donaldson CJ, Rivier J, Li C, Chen A, Vale WW 2004 Cocaine- and amphetamine-regulated transcript activates the hypothalamic- pituitary-adrenal axis through a corticotropin-releasing factor receptor-dependent mechanism. Endocrinology 145:5202-5209
8. Sarkar S, Wittmann G, Fekete C, Lechan RM 2004 Central administration of cocaine- and amphetamine-regulated transcript increases phosphorylation of cAMP response element binding protein in corticotropin-releasing hormone-producing neurons but not in prothyrotropin-releasing hormone-producing neurons in the hypothalamic paraventricular nucleus. Brain Res 999:181-192
9. Stanley SA, Small CJ, Murphy KG, Rayes E, Abbott CR, Seal LJ, Morgan DG, Sunter D, Dakin CL, Kim MS, Hunter R, Kuhar M, Ghatei MA, Bloom SR 2001 Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats. Brain Res 893:186-194
10. Seasholtz AF, Thompson RC, Douglass JO 1988 Identification of a cyclic adenosine monophosphate-responsive element in the rat corticotropin-releasing hormone gene. Mol Endocrinol 2:1311-1319
11. Fekete C, Wittmann G, Liposits Z, Lechan RM 2004 Origin of cocaine- and amphetamine-regulated transcript (CART)-immunoreactive innervation of the hypothalamic paraventricular nucleus. J Comp Neurol 469:340-350
12. Vrang N, Larsen PJ, Clausen JT, Kristensen P 1999 Neurochemical characterization of hypothalamic cocaine- amphetamine-regulated transcript neurons. J Neurosci 19:RC5
13. Liposits Z, Phelix C, Paull WK 1986 Adrenergic innervation of corticotropin releasing factor (CRF)-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. A combined light and electron microscopic immunocytochemical study. Histochemistry 84:201-205
14. Liposits Z, Sievers L, Paull WK 1988 Neuropeptide-Y and ACTH-immunoreactive innervation of corticotropin releasing factor (CRF)-synthesizing neurons in the hypothalamus of the rat. An immunocytochemical analysis at the light and electron microscopic levels. Histochemistry 88:227-234
15. Paxinos G, Watson C 1998 The rat brain in stereotaxic coordinates. 4th ed. San Diego: Academic Press
16. Bohn MC, Dreyfus CF, Friedman WJ, Markey KA 1987 Glucocorticoid effects on phenylethanolamine N-methyltransferase (PNMT) in explants of embryonic rat medulla oblongata. Brain Res 465:257-266
17. Elias CF, Saper CB, Maratos-Flier E, Tritos NA, Lee C, Kelly J, Tatro JB, Hoffman GE, Ollmann MM, Barsh GS, Sakurai T, Yanagisawa M, Elmquist JK 1998 Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. J Comp Neurol 402:442-459
18. Mihaly E, Fekete C, Lechan RM, Liposits Z 2002 Corticotropin-releasing hormone-synthesizing neurons of the human hypothalamus receive neuropeptide Y-immunoreactive innervation from neurons residing primarily outside the infundibular nucleus. J Comp Neurol 446:235-243
19. Burman KJ, Sartor DM, Verberne AJ, Llewellyn-Smith IJ 2004 Cocaine- and amphetamine-regulated transcript in catecholamine and noncatecholamine presympathetic vasomotor neurons of rat rostral ventrolateral medulla. J Comp Neurol 476:19-31
20. Dun SL, Ng YK, Brailoiu GC, Ling EA, Dun NJ 2002 Cocaine- and amphetamine-regulated transcript peptide-immunoreactivity in adrenergic C1 neurons projecting to the intermediolateral cell column of the rat. J Chem Neuroanat 23:123-132
21. Cole RL, Sawchenko PE 2002 Neurotransmitter regulation of cellular activation and neuropeptide gene expression in the paraventricular nucleus of the hypothalamus. J Neurosci 22:959-969
22. Itoi K, Helmreich DL, Lopez-Figueroa MO, Watson SJ 1999 Differential regulation of corticotropin-releasing hormone and vasopressin gene transcription in the hypothalamus by norepinephrine. J Neurosci 19:5464-5472
23. Kiss A, Aguilera G 2000 Role of α1-adrenergic receptors in the regulation of corticotropin-releasing hormone mRNA in the paraventricular nucleus of the hypothalamus during stress. Cell Mol Neurobiol 20:683-694
24. Itoi K, Suda T, Tozawa F, Dobashi I, Ohmori N, Sakai Y, Abe K, Demura H 1994 Microinjection of norepinephrine into the paraventricular nucleus of the hypothalamus stimulates corticotropin-releasing factor gene expression in conscious rats. Endocrinology 135:2177-2182
25. Day HE, Campeau S, Watson Jr SJ, Akil H 1999 Expression of α(1b) adrenoceptor mRNA in corticotropin-releasing hormone-containing cells of the rat hypothalamus and its regulation by corticosterone. J Neurosci 19:10098-10106
26. Thonberg H, Fredriksson JM, Nedergaard J, Cannon B 2002 A novel pathway for adrenergic stimulation of cAMP-response-element-binding protein (CREB) phosphorylation: mediation via α1-adrenoceptors and protein kinase C activation. Biochem J 364:73-79
27. Ritter S, Watts AG, Dinh TT, Sanchez-Watts G, Pedrow C 2003 Immunotoxin lesion of hypothalamically projecting norepinephrine and epinephrine neurons differentially affects circadian and stressor-stimulated corticosterone secretion. Endocrinology 144:1357-1367
28. Ritter S, Llewellyn-Smith I, Dinh TT 1998 Subgroups of hindbrain catecholamine neurons are selectively activated by 2-deoxy-D-glucose induced metabolic challenge. Brain Res 805:41-54
29. Li AJ, Ritter S 2004 Glucoprivation increases expression of neuropeptide Y mRNA in hindbrain neurons that innervate the hypothalamus. Eur J Neurosci 19:2147-2154
30. Ericsson A, Kovacs KJ, Sawchenko PE 1994 A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons. J Neurosci 14:897-913
31. Buller K, Xu Y, Dayas C, Day T 2001 Dorsal and ventral medullary catecholamine cell groups contribute differentially to systemic interleukin-1β-induced hypothalamic pituitary adrenal axis responses. Neuroendocrinology 73:129- 138
32. Fekete C, Singru PS, Sarkar S, Rand WM, Lechan RM 2005 Ascending brainstem pathways are not involved in lipopolysaccharide-induced suppression of TRH gene expression in the hypothalamic paraventricular nucleus. Endocrinology 146:1357-1363
33. Fekete C, Legradi G, Mihaly E, Tatro JB, Rand WM, Lechan RM 2000 α-Melanocyte stimulating hormone prevents fasting-induced suppression of corticotropin-releasing hormone gene expression in the rat hypothalamic paraventricular nucleus. Neurosci Lett 289:152-156
34. Lu XY, Barsh GS, Akil H, Watson SJ 2003 Interaction between α-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses. J Neurosci 23:7863- 7872
35. Dhillo WS, Small CJ, Seal LJ, Kim MS, Stanley SA, Murphy KG, Ghatei MA, Bloom SR 2002 The hypothalamic melanocortin system stimulates the hypothalamo-pituitary-adrenal axis in vitro and in vivo in male rats. Neuroendocrinology 75:209-216
36. Sarkar S, Legradi G, Lechan RM 2002 Intracerebroventricular administration of α-melanocyte stimulating hormone increases phosphorylation of CREB in TRH- and CRH-producing neurons of the hypothalamic paraventricular nucleus. Brain Res 945:50-59
37. Mizuno TM, Kleopoulos SP, Bergen HT, Roberts JL, Priest CA, Mobbs CV 1998 Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin. Diabetes 47:294-297
38. Kristensen P, Judge ME, Thim L, Ribel U, Christjansen KN, Wulff BS, Clausen JT, Jensen PB, Madsen OD, Vrang N, Larsen PJ, Hastrup S 1998 Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393:72-76
39. Ahima RS, Kelly J, Elmquist JK, Flier JS 1999 Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia. Endocrinology 140:4923-4931
40. Schwartz MW, Seeley RJ 1997 Seminars in medicine of the Beth Israel Deaconess Medical Center. Neuroendocrine responses to starvation and weight loss. N Engl J Med 336:1802-1811
41. Sergeyev V, Broberger C, Hokfelt T 2001 Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus. Brain Res Mol Brain Res 90:93-100
42. Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E 1998 Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396:670-674
43. Loewy AD 1990 Central autonomic pathways. In: Spyer KM, ed. Central regulation of autonomic functions.New York: Oxford University Press; 88-103
44. Raptis S, Fekete C, Sarkar S, Rand WM, Emerson CH, Nagy GM, Lechan RM 2004 Cocaine- and amphetamine-regulated transcript cocontained in thyrotropin-releasing hormone (TRH) neurons of the hypothalamic paraventricular nucleus modulates TRH-induced prolactin secretion. Endocrinology 145:1695-1699