메뉴 건너뛰기




Volumn 59, Issue 8, 2007, Pages 1077-1085

Central nervous system distribution kinetics of indinavir in rats

Author keywords

[No Author keywords available]

Indexed keywords

INDINAVIR;

EID: 34547933529     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.8.0004     Document Type: Article
Times cited : (8)

References (47)
  • 1
    • 0003832280 scopus 로고    scopus 로고
    • Physicochemical factors that influence brain uptake
    • Begley, D. J, Bradbury, M. W, Kreuter, J, eds, Marcel Dekker Inc, New York, pp
    • Abraham, M. H., Platts, J. A. (2000) Physicochemical factors that influence brain uptake. In: Begley, D. J., Bradbury, M. W., Kreuter, J. (eds) Blood-brain barrier and drug delivery to the CNS. Marcel Dekker Inc., New York, pp 9-32
    • (2000) Blood-brain barrier and drug delivery to the CNS , pp. 9-32
    • Abraham, M.H.1    Platts, J.A.2
  • 2
    • 0033001617 scopus 로고    scopus 로고
    • Acosta, E. P., Henry, K., Baken, L., Page, L. M., Fletcher, C. V. (1999) Indinavir concentrations and antiviral effect. Pharmacotherapy 19: 708-712
    • Acosta, E. P., Henry, K., Baken, L., Page, L. M., Fletcher, C. V. (1999) Indinavir concentrations and antiviral effect. Pharmacotherapy 19: 708-712
  • 3
    • 0025267249 scopus 로고
    • Uptake kinetics of 2′,3′-dideoxyinosine into brain and cerebrospinal fluid of rats: Intravenous infusion studies
    • Anderson, B. D., Hoesterey, B. L., Baker, D. C., Galinsky, R. E. (1990) Uptake kinetics of 2′,3′-dideoxyinosine into brain and cerebrospinal fluid of rats: intravenous infusion studies. J. Pharmacol. Exp. Ther. 253: 113-118
    • (1990) J. Pharmacol. Exp. Ther , vol.253 , pp. 113-118
    • Anderson, B.D.1    Hoesterey, B.L.2    Baker, D.C.3    Galinsky, R.E.4
  • 4
    • 0026700230 scopus 로고
    • Technique-dependent variations in cerebral microvessel blood volumes and hematocrits in the rat
    • Bereczki, D., Wei, L., Acuff, V., Gruber, K., Tajima, A., Patlak, C., Fenstermacher, J. (1992) Technique-dependent variations in cerebral microvessel blood volumes and hematocrits in the rat. J. Appl. Physiol. 73: 918-924
    • (1992) J. Appl. Physiol , vol.73 , pp. 918-924
    • Bereczki, D.1    Wei, L.2    Acuff, V.3    Gruber, K.4    Tajima, A.5    Patlak, C.6    Fenstermacher, J.7
  • 5
    • 0030908131 scopus 로고    scopus 로고
    • Hepatic and intestinal metabolism of indinavir, an HIV protease inhibitor, in rat and human microsomes. Major role of CYP3A
    • Chiba, M., Hensleigh, M., Lin, J. H. (1997) Hepatic and intestinal metabolism of indinavir, an HIV protease inhibitor, in rat and human microsomes. Major role of CYP3A. Biochem. Pharmacol. 53: 1187-1195
    • (1997) Biochem. Pharmacol , vol.53 , pp. 1187-1195
    • Chiba, M.1    Hensleigh, M.2    Lin, J.H.3
  • 6
    • 0034001402 scopus 로고    scopus 로고
    • Comparative in vitro metabolism of indinavir in primates - a unique stereoselective hydroxylation in monkey
    • Chiba, M., Nishime, J. A., Neway, Y., Lin, Y., Lin, J. H. (2000) Comparative in vitro metabolism of indinavir in primates - a unique stereoselective hydroxylation in monkey. Xenobiotica 30: 117-129
    • (2000) Xenobiotica , vol.30 , pp. 117-129
    • Chiba, M.1    Nishime, J.A.2    Neway, Y.3    Lin, Y.4    Lin, J.H.5
  • 7
    • 0034121122 scopus 로고    scopus 로고
    • Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testis
    • Choo, E. F., Leake, B., Wandel, C., Imamura, H., Wood, A. J., Wilkinson, G. R., Kim, R. B. (2000) Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testis. Drug. Metab. Dispos. 28: 655-660
    • (2000) Drug. Metab. Dispos , vol.28 , pp. 655-660
    • Choo, E.F.1    Leake, B.2    Wandel, C.3    Imamura, H.4    Wood, A.J.5    Wilkinson, G.R.6    Kim, R.B.7
  • 8
    • 0013793526 scopus 로고
    • The permeability of brain capillaries to non-electrolytes
    • Crone, C. (1965) The permeability of brain capillaries to non-electrolytes. Acta. Physiol. Scand. 64: 407-417
    • (1965) Acta. Physiol. Scand , vol.64 , pp. 407-417
    • Crone, C.1
  • 9
    • 0000131149 scopus 로고    scopus 로고
    • Protease inhibitors: Resistance, cross-resistance, fitness and the choice of initial and salvage therapies
    • Erickson, J. W., Gulnik, S. V., Markowitz, M. (1999) Protease inhibitors: resistance, cross-resistance, fitness and the choice of initial and salvage therapies. AIDS 13 (Suppl. A): S189-S204
    • (1999) AIDS , vol.13 , Issue.SUPPL. A
    • Erickson, J.W.1    Gulnik, S.V.2    Markowitz, M.3
  • 10
    • 0034456228 scopus 로고    scopus 로고
    • HIV-protease inhibitors
    • Eron, J. J. (2000) HIV-protease inhibitors. Clin. Infect. Dis. 30 (Suppl. 2): S160-S170
    • (2000) Clin. Infect. Dis , vol.30 , Issue.SUPPL. 2
    • Eron, J.J.1
  • 12
    • 0019783061 scopus 로고
    • Methods for quantifying the transport of drugs across brain barrier systems
    • Fenstermacher, J. D., Blasberg, R. G., Patlak, C. S. (1981) Methods for quantifying the transport of drugs across brain barrier systems. Pharmacol. Ther. 14: 217-248
    • (1981) Pharmacol. Ther , vol.14 , pp. 217-248
    • Fenstermacher, J.D.1    Blasberg, R.G.2    Patlak, C.S.3
  • 13
    • 0025140975 scopus 로고
    • Brain and cerebrospinal fluid uptake of zidovudine (AZT) in rats after intravenous injection
    • Galinsky, R. E., Hoesterey, B. L., Anderson, B. D. (1990) Brain and cerebrospinal fluid uptake of zidovudine (AZT) in rats after intravenous injection. Life. Sci. 47: 781-788
    • (1990) Life. Sci , vol.47 , pp. 781-788
    • Galinsky, R.E.1    Hoesterey, B.L.2    Anderson, B.D.3
  • 16
    • 0033981738 scopus 로고    scopus 로고
    • Determination of passive drug entry into central nervous system
    • Habgood, M. D., Begley, D. J., Abbott, N. J. (2000) Determination of passive drug entry into central nervous system. Cell. Mol. Neurobiol. 20: 231-253
    • (2000) Cell. Mol. Neurobiol , vol.20 , pp. 231-253
    • Habgood, M.D.1    Begley, D.J.2    Abbott, N.J.3
  • 17
    • 0027944014 scopus 로고
    • Carotid artery stenosis and tachyarrhythmias: Regional cerebral blood flow during high-rate ventricular pacing after one vessel occlusion in rats
    • Hagendorff, A., Dettmers, C., Danos, P., Wetter, S., Lassau, M., Pizzulli, L., Omran, H., Bauer, T., Hartmann, A., Luderitz, B. (1994) Carotid artery stenosis and tachyarrhythmias: regional cerebral blood flow during high-rate ventricular pacing after one vessel occlusion in rats. J. Clin. Invest. 72: 775-781
    • (1994) J. Clin. Invest , vol.72 , pp. 775-781
    • Hagendorff, A.1    Dettmers, C.2    Danos, P.3    Wetter, S.4    Lassau, M.5    Pizzulli, L.6    Omran, H.7    Bauer, T.8    Hartmann, A.9    Luderitz, B.10
  • 18
    • 33645735401 scopus 로고    scopus 로고
    • Simple and sensitive high-performance liquid chromatography method for the quantitation of indinavir in rat plasma and central nervous system
    • Hamidi, M. (2006a) Simple and sensitive high-performance liquid chromatography method for the quantitation of indinavir in rat plasma and central nervous system. J. Sep. Sci. 29: 620-627
    • (2006) J. Sep. Sci , vol.29 , pp. 620-627
    • Hamidi, M.1
  • 19
    • 33745967704 scopus 로고    scopus 로고
    • Role of P-glycoprotein in tissue uptake of indinavir in rat
    • Hamidi, M. (2006b) Role of P-glycoprotein in tissue uptake of indinavir in rat. Life Sci. 79: 991-998
    • (2006) Life Sci , vol.79 , pp. 991-998
    • Hamidi, M.1
  • 20
    • 0024230927 scopus 로고
    • Neutral amino acid transport at the human blood-brain barrier
    • Hargreaves, K. M., Pardridge, W. M. (1988) Neutral amino acid transport at the human blood-brain barrier. J. Biol. Chem. 263: 19 392-19 397
    • (1988) J. Biol. Chem , vol.263
    • Hargreaves, K.M.1    Pardridge, W.M.2
  • 21
    • 0027478603 scopus 로고
    • Localization of immunoreactive glutamyl aminopeptidase in rat brain. II. Distribution and correlation with angiotensin II
    • Healy, D. P., Wilks, S. (1993) Localization of immunoreactive glutamyl aminopeptidase in rat brain. II. Distribution and correlation with angiotensin II. Brain Res. 606: 295-303
    • (1993) Brain Res , vol.606 , pp. 295-303
    • Healy, D.P.1    Wilks, S.2
  • 23
    • 0025126177 scopus 로고
    • A morphometric study on the development of the lateral ventricle choroid plexus, choroid plexus capillaries and ventricular ependyma in the rat
    • Keep, R. F., Jones, H. C. (1990) A morphometric study on the development of the lateral ventricle choroid plexus, choroid plexus capillaries and ventricular ependyma in the rat. Brain Res. Dev. Brain Res. 56: 47-53
    • (1990) Brain Res. Dev. Brain Res , vol.56 , pp. 47-53
    • Keep, R.F.1    Jones, H.C.2
  • 24
    • 0032518290 scopus 로고    scopus 로고
    • The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
    • Kim, R. B., Fromm, M. F., Wandel, C., Leake, B., Wood, A. J., Roden, D. M., Wilkinson, G. R. (1998) The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J. Clin. Invest. 101: 289-294
    • (1998) J. Clin. Invest , vol.101 , pp. 289-294
    • Kim, R.B.1    Fromm, M.F.2    Wandel, C.3    Leake, B.4    Wood, A.J.5    Roden, D.M.6    Wilkinson, G.R.7
  • 27
    • 0029974065 scopus 로고    scopus 로고
    • Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor
    • Lin, J. H., Chiba, M., Balani, S. K., Chen, I. W., Kwei, G. Y., Vastag, K. J., Nishime, J. A. (1996) Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor. Drug. Metab. Dispos. 24: 1111-1120
    • (1996) Drug. Metab. Dispos , vol.24 , pp. 1111-1120
    • Lin, J.H.1    Chiba, M.2    Balani, S.K.3    Chen, I.W.4    Kwei, G.Y.5    Vastag, K.J.6    Nishime, J.A.7
  • 28
    • 0032788076 scopus 로고    scopus 로고
    • Indinavir-based treatment of HIV-1-infected patients: Efficacy in the central nervous system
    • Martin, C., Sonnerborg, A., Svensson, J. O., Stahle, L. (1999) Indinavir-based treatment of HIV-1-infected patients: efficacy in the central nervous system. AIDS 13: 1227-1232
    • (1999) AIDS , vol.13 , pp. 1227-1232
    • Martin, C.1    Sonnerborg, A.2    Svensson, J.O.3    Stahle, L.4
  • 29
    • 0037081556 scopus 로고    scopus 로고
    • A co-culture-based model of human blood-brain barrier: Application to active transport of indinavir and in vivo-in vitro correlation
    • Megard, I., Garrigues, A., Orlowski, S., Jorajuria, S., Clayette, P., Ezan, E., Mabondzo, A. (2002) A co-culture-based model of human blood-brain barrier: application to active transport of indinavir and in vivo-in vitro correlation. Brain. Res. 927: 153-167
    • (2002) Brain. Res , vol.927 , pp. 153-167
    • Megard, I.1    Garrigues, A.2    Orlowski, S.3    Jorajuria, S.4    Clayette, P.5    Ezan, E.6    Mabondzo, A.7
  • 30
    • 0018237164 scopus 로고
    • Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat
    • Ohno, K., Pettigrew, K. D., Rapoport, S. I. (1978) Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am. J. Physiol. 235: H299-H307
    • (1978) Am. J. Physiol , vol.235
    • Ohno, K.1    Pettigrew, K.D.2    Rapoport, S.I.3
  • 31
    • 0025329190 scopus 로고
    • Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier
    • Pardridge, W. M., Triguero, D., Yang, J., Cancilla, P. A. (1990) Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier. J. Pharmacol. Exp. Ther. 253: 884-891
    • (1990) J. Pharmacol. Exp. Ther , vol.253 , pp. 884-891
    • Pardridge, W.M.1    Triguero, D.2    Yang, J.3    Cancilla, P.A.4
  • 32
    • 0030791962 scopus 로고    scopus 로고
    • Central nervous system as a sanctuary for HIV-1 infection despite treatment with zidovudine, lamivudine and indinavir
    • Pialoux, G., Fournier, S., Moulignier, A., Poveda, J. D., Clavel, F., Dupont, B. (1997) Central nervous system as a sanctuary for HIV-1 infection despite treatment with zidovudine, lamivudine and indinavir. AIDS 11: 1302-1303
    • (1997) AIDS , vol.11 , pp. 1302-1303
    • Pialoux, G.1    Fournier, S.2    Moulignier, A.3    Poveda, J.D.4    Clavel, F.5    Dupont, B.6
  • 33
    • 13344292421 scopus 로고
    • Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscle
    • Renkin, E. M. (1959) Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscle. Am. J. Physiol. 197: 1205-1210
    • (1959) Am. J. Physiol , vol.197 , pp. 1205-1210
    • Renkin, E.M.1
  • 34
    • 0022490282 scopus 로고
    • Continuous measurement of cerebral blood volume in rats with the photoelectric technique: Effect of morphine and naloxone
    • Sandor, P., Cox-van Put, J., deJong, W., de Wied, D. (1986) Continuous measurement of cerebral blood volume in rats with the photoelectric technique: effect of morphine and naloxone. Life Sci. 39: 1657-1665
    • (1986) Life Sci , vol.39 , pp. 1657-1665
    • Sandor, P.1    Cox-van Put, J.2    deJong, W.3    de Wied, D.4
  • 36
    • 0023682578 scopus 로고
    • Kinetics and distribution volumes for tracers of different sizes in the brain plasma space
    • Smith, Q. R., Ziylan, Y. Z., Robinson, P. J., Rapoport, S. I. (1988) Kinetics and distribution volumes for tracers of different sizes in the brain plasma space. Brain Res. 462: 1-9
    • (1988) Brain Res , vol.462 , pp. 1-9
    • Smith, Q.R.1    Ziylan, Y.Z.2    Robinson, P.J.3    Rapoport, S.I.4
  • 37
    • 0030954863 scopus 로고    scopus 로고
    • Distributed model analysis of 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine distribution in brain tissue and cerebrospinal fluid
    • Takasawa, K., Terasaki, T., Suzuki, H., Ooie, T., Sugiyama, Y. (1997a) Distributed model analysis of 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine distribution in brain tissue and cerebrospinal fluid. J. Pharmacol. Exp. Ther. 282: 1509-1517
    • (1997) J. Pharmacol. Exp. Ther , vol.282 , pp. 1509-1517
    • Takasawa, K.1    Terasaki, T.2    Suzuki, H.3    Ooie, T.4    Sugiyama, Y.5
  • 38
    • 0030977086 scopus 로고    scopus 로고
    • In vivo evidence for carrier-mediated efflux transport of 3′-azido-3′- deoxythymidine and 2′,3′-dideoxyinosine across the blood-brain barrier via a probenecid-sensitive transport system
    • Takasawa, K., Terasaki, T., Suzuki, H., Sugiyama, Y. (1997b) In vivo evidence for carrier-mediated efflux transport of 3′-azido-3′- deoxythymidine and 2′,3′-dideoxyinosine across the blood-brain barrier via a probenecid-sensitive transport system. J. Pharmacol. Exp. Ther. 281: 369-375
    • (1997) J. Pharmacol. Exp. Ther , vol.281 , pp. 369-375
    • Takasawa, K.1    Terasaki, T.2    Suzuki, H.3    Sugiyama, Y.4
  • 39
  • 40
    • 0026774071 scopus 로고
    • Cerebral blood flow, blood volume, and brain tissue hematocrit during isovolemic hemodilution with hetastarch in rats
    • Todd, M. M., Weeks, J. B., Warner, D. S. (1992) Cerebral blood flow, blood volume, and brain tissue hematocrit during isovolemic hemodilution with hetastarch in rats. Am. J. Physiol. 263: H75-H82
    • (1992) Am. J. Physiol , vol.263
    • Todd, M.M.1    Weeks, J.B.2    Warner, D.S.3
  • 41
    • 0009149229 scopus 로고    scopus 로고
    • Specific mechanisms for transporting drugs into brain
    • Begley, D. J, Bradbury, M. W, Kreuter, J, eds, Marcel Dekker Inc, New York, pp
    • Tsuji, A. (2000) Specific mechanisms for transporting drugs into brain. In: Begley, D. J., Bradbury, M. W., Kreuter, J. (eds) Blood-brain barrier and drug delivery to the CNS. Marcel Dekker Inc., New York, pp 121-144
    • (2000) Blood-brain barrier and drug delivery to the CNS , pp. 121-144
    • Tsuji, A.1
  • 42
    • 0035831246 scopus 로고    scopus 로고
    • Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood-brain barrier
    • van der Sandt, I. C., Vos, C. M., Nabulsi, L., Blom-Roosemalen, M. C., Voorwinden, H. H., de Boer, A. G., Breimer, D. D. (2001) Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood-brain barrier. AIDS 15: 483-491
    • (2001) AIDS , vol.15 , pp. 483-491
    • van der Sandt, I.C.1    Vos, C.M.2    Nabulsi, L.3    Blom-Roosemalen, M.C.4    Voorwinden, H.H.5    de Boer, A.G.6    Breimer, D.D.7
  • 43
    • 0029013672 scopus 로고
    • Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion
    • Wang, Y., Sawchuk, R. J. (1995) Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion. J. Pharm. Sci. 84: 871-876
    • (1995) J. Pharm. Sci , vol.84 , pp. 871-876
    • Wang, Y.1    Sawchuk, R.J.2
  • 46
    • 0000969952 scopus 로고
    • Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients
    • Wiley, C. A., Schrier, R. D., Nelson, J. A., Lampert, P. W., Old-stone, M. B. (1986) Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc. Natl. Acad. Sci. USA 83: 7089-7093
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 7089-7093
    • Wiley, C.A.1    Schrier, R.D.2    Nelson, J.A.3    Lampert, P.W.4    Old-stone, M.B.5
  • 47
    • 0032571761 scopus 로고    scopus 로고
    • Low blood-brain barrier permeability to azidothymidine (AZT), 3TC, and thymidine in the rat
    • Wu, D., Clement, J. G., Pardridge, W. M. (1998) Low blood-brain barrier permeability to azidothymidine (AZT), 3TC, and thymidine in the rat. Brain. Res. 791: 313-316
    • (1998) Brain. Res , vol.791 , pp. 313-316
    • Wu, D.1    Clement, J.G.2    Pardridge, W.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.