An importin α/β-recognized bipartite nuclear localization signal mediates targeting of the human herpes simplex virus type 1 DNA polymerase catalytic subunit pUL30 to the nucleus

Biochemistry

Volumn 46, Issue 32, 2007, Pages 9155-9163

  Alvisi, Gualtiero ^a,b   Musiani, Daniele ^a   Jans, David A ^b,c   Ripalti, Alessandro ^d  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b MONASH UNIVERSITY   (Australia)

^c Dipartimento di Patologia Clinica Microbiologia e Medicina Trasfusionale   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CONFOCAL LASER SCANNING MICROSCOPY (CLSM); LOCALIZATION SIGNAL (NLS); POLYMERASE ACCESSORY PROTEIN;

AMINO ACIDS; BINDING ENERGY; CELLS; CONFOCAL MICROSCOPY; DISEASES;

ENZYMES;

AMINO ACID; DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; HETERODIMER; KARYOPHERIN ALPHA; KARYOPHERIN BETA; POLYMERASE ACCESSORY PROTEIN; PROTEIN PUL30; PROTEIN PUL54; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVE SITE; HERPES SIMPLEX VIRUS 1; HOST CELL; HUMAN CYTOMEGALOVIRUS; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; VIRUS CELL INTERACTION; VIRUS REPLICATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ALPHA KARYOPHERINS; AMINO ACID SEQUENCE; ANIMALS; BETA KARYOPHERINS; CATALYTIC DOMAIN; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; DIMERIZATION; DNA-DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASES; GENE TARGETING; HERPESVIRUS 1, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR LOCALIZATION SIGNALS; PROLINE; PROTEIN ISOFORMS; SIGNAL TRANSDUCTION; VERO CELLS; VIRAL PROTEINS;

HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 5;

EID: 34547920745     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7002394     Document Type: Article

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