Multiple mechanisms of Erbb2 action after ultraviolet irradiation of the skin

Molecular Carcinogenesis

Volumn 46, Issue 8, 2007, Pages 624-628

  Madson, Justin G ^a   Hansen, Laura A ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Epidermis; Inflammation; Nonmelanoma; Proliferation

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2;

ANGIOGENESIS; APOPTOSIS; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL DIVISION; CELL MIGRATION; CELL PROLIFERATION; CONFERENCE PAPER; GENE EXPRESSION; INFLAMMATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATOR GENE; SIGNAL TRANSDUCTION; SKIN CARCINOGENESIS; SKIN CARCINOMA; ULTRAVIOLET IRRADIATION;

CELL PROLIFERATION; GENE EXPRESSION REGULATION; HUMANS; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; SKIN; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 34547908179     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20335     Document Type: Conference Paper

References (27)

1. Xu Y, Shao Y, Voorhees JJ, Fisher GJ. Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes. J Biol Chem 2006;281:27389-27397.
2. Madson JG, Lynch DT, Tinkum KL, Putta SK, Hansen LA. Erbb2 regulates inflammation and proliferation in the skin following ultraviolet irradiation. Am J Pathol 2006;69:1402-1414.
3. Marchese C, Maresca V, Cardinali G, et al. UVB-induced activation and internalization of keratinocyte growth factor receptor. Oncogene 2003;22:2422-2431.
4. Bender K, Blattner C, Knebel A, Iordanov M, Herrlich P, Rahmsdorf HJ. UV-induced signal transduction. J Photochem Photobiol B 1997;37:1-17.
5. Hansen LA, Alexander N, Hogan ME, et al. Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. Am J Pathol 1997;150:1959-1975.
6. El Abaseri TB, Fuhrman J, Trempus C, Shendrik I, Tennant RW, Hansen LA. Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor. Cancer Res 2005;65:3958-3965.
7. Yu D, Hung MC. Role of erbB2 in breast cancer chemosensitivity. Bioessays 2000;22:673-680.
8. Slamon DJ, Godolphin W, Jones LA, et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989;244:707-712.
9. Beckers J, Herrmann F, Rieger S, et al. Identification and validation of novel ERBB2 (HER2, NEU) targets including genesinvolved in angiogenesis. Int J Cancer 2005;114:590-597.
10. Loureiro RM, Maharaj AS, Dankort D, Muller WJ, D'Amore PA. ErbB2 overexpression in mammary cells upregulates VEGF through the core promoter. Biochem Biophys Res Commun 2005;326:455-465.
11. Roh H, Pippin J, Drebin JA. Down-regulation of HER2/neu expression induces apoptosis in human cancer cells that overexpress HER2/neu. Cancer Res 2000;60:560-565.
12. Tovey SM, Witton CJ, Bartlett JM, Stanton PD, Reeves JR, Cooke TG. Outcome and human epidermal growth factor receptor (HER) 1-4status in invasive breast carcinomas with proliferation indices evaluated by bromodeoxyuridine labelling. Breast Cancer Res 2004;6:R246-251.
13. Joensuu H, Kellokumpu-Lehtinen PL, Bono P, et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N Engl J Med 2006;354:809-820.
14. Ahmed NU, Ueda M, Ichihashi M. Increased level of c-erbB-2/neu/HER-2 protein in cutaneous squamous cell carcinoma. Br J Dermatol 1997;136:908-912.
15. Krahn G, Leiter U, Kaskel P, et al. Coexpression patterns of EGFR, HER2, HER3 and HER4 in non-melanoma skin cancer. Eur J Cancer 2001;37:251-259.
16. De Potter IY, Poumay Y, Squillace KA, Pittelkow MR. Human EGF receptor (HER) family and heregulin members are differentially expressed in epidermal keratinocytes and modulate differentiation. Exp Cell Res 2001;271:315-328.
17. Liu B, Zhang H, Li S, Chen W, Li R. The expression of c-erbB-1 and c-erbB-2 oncogenes in basal cell carcinoma and squamous cell carcinoma of skin. Chin Med Sci J 1996;11:106-109.
18. Marques MM, Martinez N, Rodriguez-Garcia I, Alonso A. EGFR family-mediated signal transduction in the human keratinocyte cell line HaCaT. Exp Cell Res 1999;252:432-438.
19. Roberts RB, Arteaga CL, Threadgill DW. Modeling the cancer patient with genetically engineered mice: Prediction of toxicity from molecule-targeted therapies. Cancer Cell 2004;5:115-120.
20. Kiguchi K, Bol D, Carbajal S, et al. Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development. Oncogene 2000;19:4243-4254.
21. Xie W, Wu X, Chow LT, Chin E, Paterson AJ, Kudlow JE. Targeted expression of activated erbB-2 to the epidermis of transgenic mice elicits striking developmental abnormalities in the epidermis and hair follicles. Cell Growth Differ 1998;9:313-325.
22. Xian W, Rosenberg MP, DiGiovanni J. Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: possible role in mouse skin tumor promotion. Oncogene 1997;14:1435-1444.
23. Tagliabue E, Agresti R, Carcangiu ML, et al. Role of HER2 in wound-induced breast carcinoma proliferation. Lancet 2003;362:527-533.
24. Repertinger SK, Campagnaro E, Fuhrman J, El Abaseri T, Yuspa SH, Hansen LA. EGFR enhances early healing after cutaneous incisional wounding. J Invest Dermatol 2004;123:982-989.
25. Kheradmand F, Werner E, Tremble P, Symons M, Werb Z. Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change. Science 1998;280:898-902.
26. Bol D, Kiguchi K, Beltran L, et al. Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing the neu oncogene under the control of the bovine keratin 5 promoter. Mol Carcinog 1998;21:2-12.
27. Xie W, Chow LT, Paterson AJ, Chin E, Kudlow JE. Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice. Oncogene 1999;18:3593-3607.