Acute oral toxicity of colchicine in rats: Effects of gender, vehicle matrix and pre-exposure to lipopolysaccharide

Journal of Applied Toxicology

Volumn 27, Issue 5, 2007, Pages 421-433

  Wiesenfeld, Paddy L ^a,b   Garthoff, Larry H ^a   Sobotka, Thomas J ^a   Suagee, Jessica K ^a   Barton, Curtis N ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b HFS 025 ^*  (United States)

Author keywords

Colchicine; Half and Half cream; Lethality; Lipopolysaccharide; Oral; Rats; Toxicity

Indexed keywords

COLCHICINE; ESTROGEN; LIPOPOLYSACCHARIDE; SODIUM CHLORIDE; TESTOSTERONE;

ANIMAL EXPERIMENT; ANOREXIA; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; FOOD INTAKE; LETHALITY; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; TERATOGENICITY;

ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; COLCHICINE; FEMALE; LETHAL DOSE 50; LIPOPOLYSACCHARIDES; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; VEHICLES;

ANIMALIA; RATTUS;

EID: 34547901755     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1198     Document Type: Article

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