A mechanism underlying the sexually dimorphic ACTH response to lipopolysaccharide in rats: Sex steroid modulation of cytokine binding sites in the hypothalamus

Journal of Physiology

Volumn 547, Issue 1, 2003, Pages 221-232

  Watanobe, Hajime ^a   Yoneda, Masashi ^b  

^a INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^b DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGIPRESSIN; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; CYTOKINE; ESTRADIOL; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; SEX HORMONE; TESTOSTERONE; TUMOR NECROSIS FACTOR ALPHA; PROGESTERONE;

ADENOHYPOPHYSIS; ANIMAL TISSUE; BINDING AFFINITY; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; CORTICOTROPIN RELEASE; FEMALE; GONADECTOMY; HORMONE RESPONSE; HYPOTHALAMUS; MALE; MODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; RAT; REVIEW; SENSITIVITY ANALYSIS; SEX DIFFERENCE; ADULT; ANIMAL EXPERIMENT; ARTICLE; CYTOKINE RESPONSE; HORMONE SUBSTITUTION; MEDIOBASAL HYPOTHALAMUS; TISSUE LEVEL;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ARGININE VASOPRESSIN; CORTICOTROPIN-RELEASING HORMONE; CYTOKINES; ESTROGENS; FEMALE; GONADAL STEROID HORMONES; HYPOTHALAMUS, ANTERIOR; HYPOTHALAMUS, MIDDLE; INTERLEUKIN-1; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; ORCHIECTOMY; OVARIECTOMY; RATS; RATS, WISTAR; SEX CHARACTERISTICS; TESTOSTERONE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037440724     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.032169     Document Type: Review

References (61)

1. Ban E, Milon G, Prudhomme N, Fillion G & Haour F (1991). Receptors for interleukin-1 (α and β) in mouse brain: mapping and neuronal localization in hippocampus. Neuroscience 43, 21-30.
2. Bohler HC, Zoeller RT, King JC, Rubin BS, Weber R & Merriam GR (1990). Corticotropin releasing hormone mRNA is elevated on the afternoon of proestrus in the parvocellular paraventricular nuclei of the female rat. Mol Brain Res 8, 259-262.
3. 125I-containing acylating agent. Biochem J 133, 529-539.
4. Broad KD, Keverne EB & Kendrick KM (1995). Corticotropin releasing factor mRNA expression in the sheep brain during pregnancy, parturition and lactation and following exogenous progesterone and oestrogen treatment. Mol Brain Res 29, 310-316.
5. Broadwell RD & Brightman MW (1976). Entry of peroxidase into neurons of the central and peripheral nervous systems from extracerebral and cerebral blood. J Comp Neurol 166, 257-283.
6. Chisari A, Carino M, Perone M, Gaillard RC & Spinedi E (1995). Sex and strain variability in the rat hypothalamo-pituitary-adrenal (HPA) axis function. J Endocrinol Invest 18, 25-33.
7. Corchero J, Manzanares J & Fuentes JA (2001). Role of gonadal steroids in the corticotropin-releasing hormone and proopiomelanocortin gene expression response to Delta (9)-tetrahydrocannabinol in the hypothalamus of the rat. Neuroendocrinology 74, 185-192.
8. Cornfield LJ & Sills MA (1991). High affinity interleukin-6 binding sites in bovine hypothalamus. Eur J Pharmacol 202, 113-115.
9. Cornish-Bowden A & Koshland DE (1975). Diagnostic uses of the Hill (Logit and Nernst) plots. J Mol Biol 95, 201-212.
10. de Vries GJ, Duetz W, Buijs RM, van Heerikhuize J & Vreeburg JT (1986). Effects of androgens and estrogens on the vasopressin and oxytocin innervation of the adult rat brain. Brain Res 399, 296-302.
11. de Vries GJ, Wang Z, Bullock NA & Numan S (1994). Sex differences in the effects of testosterone and its metabolites on vasopressin messenger RNA levels in the bed nucleus of the stria terminalis of rats. J Neurosci 14, 1789-1794.
12. Elisasser TH, Caperna TJ & Fayer R (1991). Tumor necrosis factor-α affects growth hormone secretion by a direct pituitary interaction. Proc Soc Exp Biol Med 198, 547-554.
13. Farrar WL, Kilian PL, Ruff MR, Hill JM & Pert CB (1987). Visualization and characterization of interleukin 1 receptors in brain. J Immunol 139, 459-463.
14. Forsling ML (1993). The influence of gonadal steroids on the release and actions of neurohypophysial hormones. Regul Pept 45, 193-196.
15. Frederic F, Oliver C, Wollman E, Delhaye-Bouchaud N & Mariani J (1993). IL-1 and LPS induce a sexually dimorphic response of the hypothalamo-pituitary-adrenal axis in several mouse strains. Eur Cytokine Netw 4, 321-329.
16. Freeman ME (1988). The ovarian cycle of the rat. In The Physiology of Reproduction, ed. Knobil E & Neill J, pp. 1893-1928. Raven Press, New York.
17. Gadient RA & Otten U (1993). Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus. Neurosci Lett 153, 13-16.
18. Greer ER, Caldwell JD, Johnson MF, Prange AJ & Pedersen CA (1986). Variations in concentration of oxytocin and vasopressin in the paraventricular nucleus of the hypothalamus during the estrous cycle in rats. Life Sci 38, 2311-2318.
19. Haas DA & George S (1988). Gonadal regulation of corticotropin-releasing factor immunoreactivity in hypothalamus. Brain Res Bull 20, 361-367.
20. Hadid R, Spinedi E, Daneva T, Grau G & Gaillard RC (1995). Repeated endotoxin treatment decreases immune and hypothalamo-pituitary-adrenal axis responses: Effects of orchidectomy and testosterone therapy. Neuroendocrinology 62, 348-355.
21. Handa RJ, Burgess LH, Kerr JE & O'Keefe JA (1994). Gonadal steroid hormone receptors and sex differences in the hypothalamo-pituitary-adrenal axis. Horm Behav 28, 464-476.
22. Haour FG, Ban EM, Milon GM, Baran D & Fillion GM (1990). Brain interleukin 1 receptors: characterization and modulation after lipopolysaccharide injection. Prog Neuroendocrinimmunol 3, 196-204.
23. Kakizaki Y, Watanobe H, Kohsaka A & Suda T (1999). Temporal profiles of interleukin-1β, interleukin-6, and tumor necrosis factor-α in the plasma and hypothalamic paraventricular nucleus after intravenous or intraperitoneal administration of lipopolysaccharide in the rat: Estimation by push-pull perfusion. Endocr J 46, 487-496.
24. Katsuura G, Gottschall PE & Arimura A (1988). Identification of a high-affinity receptor for interleukin-1 beta in rat brain. Biochem Biophys Res Commun 156, 61-67.
25. Kinouchi K, Brown G, Pasternak G & Donner DB (1991). Identification and characterization of receptors for tumor necrosis factor-α in the brain. Biochem Biophys Res Commun 181, 1532-1538.
26. Kuhn C & Francis R (1997). Gender difference in cocaine-induced HPA axis activation. Neuropsychopharmacol 16, 399-407.
27. Marquette C, Van Dan AM, Ban E, Laniece P, Crumeyrolle-Arias M, Fillion G, Berkenbosch F & Haour F (1995). Rat interleukin-1β binding sites in rat hypothalamus and pituitary gland. Neuroendocrinology 62, 362-369.
28. Nappi RE, Bonneau MJ & Rivest S (1997). Influence of the estrous cycle on c-fos and CRH gene transcription in the brain of endotoxin-challenged female rats. Neuroendocrinology 65, 29-46.
29. Ohmichi M, Hirota K, Koike K, Kurachi H, Ohtsuka S, Matsuzaki N, Yamaguchi M, Miyake A & Tanizawa O (1992). Binding sites for interleukin-6 in the anterior pituitary gland. Neuroendocrinology 55, 199-203.
30. Olchovsky D, Song J, Gelato MC, Sherwood J, Spatola E, Bruno JF & Berelowitz M (1993). Pituitary and hypothalamic insulin-like growth factor-I (IGF-I) and IGF-I receptor expression in food-deprived rats. Mol Cell Endocrinol 93, 193-198.
31. Patchev VK & Almeida OF (1996). Gonadal steroids exert facilitating and "buffering" effects on glucocorticoid-mediated transcriptional regulation of corticotropin-releasing hormone and corticosteroid receptor genes in rat brain. J Neurosci 16, 7077-7084.
32. Patchev VK, Hayashi S, Orikasa C & Almeida OF (1995). Implications of estrogen-dependent brain organization for gender differences in hypothalamo-pituitary-adrenal regulation. FASEB J 9, 419-423.
33. Paulmyer-Lacroix O, Hery M, Pugeat M & Grino M (1996). The modulatory role of estrogens on corticotropin-releasing factor gene expression in the hypothalamic paraventricular nucleus of ovariectomized rats: Role of the adrenal gland. J Neuroendocrinol 8, 515-519.
34. Rivier C (1994). Stimulatory effect of interleukin- 1 # on the hypothalamic-pituitary-adrenal axis of the rat: Influence of age, gender and circulating sex steroids. J Endocrinol 140, 365-372.
35. Rivier C (1999). Gender, sex steroids, corticotropin-releasing factor, nitric oxide, and the HPA response to stress. Pharmacol Biochem Behav 64, 739-751.
36. Roy BN, Reid RL & Van Vugt DA (1999). The effects of estrogen and progesterone on corticotropin-releasing hormone and arginine vasopressin messenger ribonucleic acid levels in the paraventricular nucleus and supraoptic nucleus of the rhesus monkey. Endocrinology 140, 2191-2198.
37. Scatchard. G (1949). The attractions of proteins for small molecules and ions. Ann NY Acad Sci 51, 660-672.
38. Schöbitz B, Voorhuis DA & De Kloet ER (1992). Localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain. Neurosci Lett 136, 189-192.
39. Spinedi E, Gaillard RC & Chisari A (2002). Sexual dimorphism of neuroendocrine-immune interactions. In Neuroendocrine-Immune Interactions, ed. Gaillard RC, pp. 91-107. Karger, Basel, Switzerland.
40. Spinedi E, Salas M, Chisari A, Perone M, Carino M & Gaillard RC (1994). Sex differences in the hypothalamo-pituitary-adrenal axis response to inflammatory and neuroendocrine stressors. Neuroendocrinology 60, 609-617.
41. Spinedi E, Suescun MO, Hadid R, Daneva T & Gaillard RC (1992). Effects of gonadectomy and sex hormone therapy on the endotoxin-stimulated hypothalamo-pituitary-adrenal axis: Evidence for a neuroendocrine-immunological sexual dimorphism. Endocrinology 131, 2430-2436.
42. Takenaka A, Takahashi S & Noguchi T (1996). Effect of protein nutrition on insulin-like growth factor-I (IGF-I) receptor in various tissues of rats. J Nutr Sci Vitaminol (Tokyo) 42, 347-357.
43. Turnbull AV & Rivier CL (1999). Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action. Physiol Rev 79, 1-71.
44. Vamvakopoulos NC & Chrousos GP (1993). Evidence of direct estrogenic regulation of human corticotropin-releasing hormone gene expression. Potential implications for the sexual dimorphism of the stress response and immune/inflammatory reaction. J Clin Invest 92, 1896-1902.
45. van Leeuwen FW, Caffe AR & De Vries GJ (1985). Vasopressin cells in the bed nucleus of the stria terminalis of the rat: sex differences and the influence of androgens. Brain Res 325, 391-394.
46. Van Tol HH, Bolwerk EL, Liu B & Burbach JP (1988). Oxytocin and vasopressin gene expression in the hypothalamo-neurohypophyseal system of the rat during the estrous cycle, pregnancy, and lactation. Endocrinology 122, 945-951.
47. Viau V, Chu A, Soriano L & Dallman MF (1999). Independent and overlapping effects of corticosterone and testosterone on corticotropin-releasing hormone and arginine vasopressin mRNA expression in the paraventricular nucleus of the hypothalamus and stress-induced adrenocorticotropic hormone release. J Neurosci 19, 6684-6693.
48. Viau V & Meaney MJ (1996). The inhibitory effect of testosterone on hypothalamic-pituitary-adrenal responses to stress is mediated by the medial preoptic area. J Neurosci 16, 1866-1876.
49. Wang Z & De Vries GL (1995). Androgen and estrogen effects on vasopressin messenger RNA expression in the medial amygdaloid nucleus in male and female rats. J Neuroendocrinol 7, 827-831.
50. Watanobe H (2002). Sexual dimorphism in the pituitary-adrenal response to tumor necrosis factor-α, but not to interleukin-6, in the rat. Brain Res Bull 57, 151-155.
51. Watanobe H, Anzai J, Nigawara T, Habu S & Takebe K (1996). Effects of gender and gonadectomy on ACTH response to interleukin-1β in the rat: Comparison with the modulation of ACTH response to immobilization stress. Neuroimmunomodulation 3, 254-258.
52. Watanobe H, Sasaki S & Takebe K (1991). Evidence that intravenous administration of interleukin-1 stimulates corticotropin-releasing hormone secretion in the median eminence of freely moving rats: Estimation by push-pull perfusion. Neurosci Lett 133, 7-10.
53. Watanobe H & Schiöth HB (2002). Postnatal profile of plasma leptin concentrations in male and female rats: Relation with the maturation of the pituitary-gonadal axis. Regul Pept 105, 23-28.
54. Watanobe H & Takebe K (1987a). Role of postnatal gonadal function in the determination of thyrotropin (TSH) releasing hormone-induced TSH response in adult male and female rats. Endocrinology 120, 1711-1718.
55. Watanobe H & Takebe K (1987b). Involvement of postnatal gonads in the maturation of dopaminergic regulation of prolactin secretion in male rats. Endocrinology 120, 2205-2211.
56. Watanobe H & Takebe K (1987c). Involvement of postnatal gonads in the maturation of dopaminergic regulation of prolactin secretion in female rats. Endocrinology 120, 2212-2219.
57. Watanobe H & Takebe K (1992). Intravenous administration of tumor necrosis factor-α stimulates corticotropin releasing hormone secretion in the push-pull cannulated median eminence of freely moving rats. Neuropeptides 22, 81-84.
58. Watanobe H & Takebe K (1993). Intrahypothalamic perfusion with interleukin-1-beta stimulates the local release of corticotropin-releasing hormone and arginine vasopressin and the plasma adrenocorticotropin in freely moving rats: A comparative perfusion of the paraventricular nucleus and the median eminence. Neuroendocrinology 57, 593-599.
59. Watanobe H & Takebe K (1994). Effects of intravenous administration of interleukin-1-beta on the release of prostaglandin E2, corticotropin-releasing factor, and arginine vasopressin in several hypothalamic areas of freely moving rats: Estimation by push-pull perfusion. Neuroendocrinology 60, 8-15.
60. Wolvers DA, Marquette C, Berkenbosch F & Haour F (1993). Tumor necrosis factor-α: specific binding sites in rodent brain and pituitary gland. Eur Cytokine Netw 4, 377-381.
61. Yabuuchi K, Minami M, Katsumata S & Satoh M (1994). Localization of type I interleukin-1 receptor mRNA in the rat brain. Mol Brain Res 27, 27-36.