Staphylococcus aureus-superantigen decreases FKBP51 mRNA expression and cell-response to suppressive efficacy of a glucocorticoid in human peripheral blood mononuclear cells: Possible implication of mitogen-activated protein kinase pathways

European Journal of Pharmacology

Volumn 570, Issue 1-3, 2007, Pages 222-228

  Fukushima, Hisayo ^a   Hirano, Toshihiko ^a   Oka, Kitaro ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

C jun N terminal kinase; Glucocorticoid; Interleukin 2; Superantigens; Toxic shock syndrome toxin 1

Indexed keywords

BACTERIAL ANTIGEN; CONCANAVALIN A; CYTOKINE; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 51; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PREDNISOLONE; STRESS ACTIVATED PROTEIN KINASE; TOXIC SHOCK SYNDROME TOXIN 1; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOMETRY; DRUG EFFICACY; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IC 50; IMMUNOSUPPRESSIVE TREATMENT; MALE; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; STAPHYLOCOCCUS AUREUS; SUPERNATANT;

ADULT; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; CELLS, CULTURED; CYTOKINES; ENTEROTOXINS; FEMALE; GLUCOCORTICOIDS; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PREDNISOLONE; RNA, MESSENGER; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS; TACROLIMUS BINDING PROTEINS;

EID: 34547849661     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.05.021     Document Type: Article

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