Bacterial superantigen TSST-1 attenuates suppressive efficacy of glucocorticoids and calcineurin inhibitors against blastogenesis of peripheral blood mononuclear cells from patients with antineutrophil cytoplasmic antibody-associated vasculitis and nephrosis

International Immunopharmacology

Volumn 6, Issue 6, 2006, Pages 924-934

  Hirano, Toshihiko ^a   Fukushima, Hisayo ^a   Sasaki, Yoshinobu ^a   Yoshikawa, Noriko ^b   Yoshida, Masaharu ^b   Oka, Kitaro ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b TOKYO MEDICAL UNIVERSITY HACHIOJI MEDICAL CENTER   (Japan)

Author keywords

Antineutrophil cytoplasmic antibody associated vasculitis; Bacterial superantigen; Calcineurin inhibitors; Glucocorticoids; Nephrosis; Peripheral blood mononuclear cells

Indexed keywords

BACTERIAL ANTIGEN; CALCINEURIN INHIBITOR; CONCANAVALIN A; CYCLOSPORIN; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; NEUTROPHIL CYTOPLASMIC ANTIBODY; PREDNISONE; SUPERANTIGEN; TACROLIMUS; THYMIDINE; TOXIC SHOCK SYNDROME TOXIN 1; TRITIUM;

ADULT; AGED; ANCA ASSOCIATED VASCULITIS; ARTICLE; CALCULATION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; FEMALE; HUMAN; HUMAN CELL; IC 50; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; LYMPHOCYTE TRANSFORMATION; MALE; NEPHROSIS; NEPHROTIC SYNDROME; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STATISTICAL SIGNIFICANCE;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; BACTERIAL TOXINS; CALCINEURIN; CELL PROLIFERATION; CONCANAVALIN A; CYCLOSPORINE; ENTEROTOXINS; FEMALE; GLUCOCORTICOIDS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INHIBITORY CONCENTRATION 50; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MALE; METHYLPREDNISOLONE; MIDDLE AGED; NEPHROSIS; PREDNISOLONE; SUPERANTIGENS; TACROLIMUS; VASCULITIS;

EID: 33646114513     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2006.01.001     Document Type: Article

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