Developing a high-throughput system for the screening of cytochrome P450 1A1 - Inhibitory polyphenols

Toxicology in Vitro

Volumn 21, Issue 6, 2007, Pages 996-1002

  Leung, Hau Yi ^a   Wang, Yun ^a   Chan, Ho Yee ^a   Leung, Lai K ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

CYP1A1; EROD; Stable transfection

Indexed keywords

2 HYDROXYCHALCONE; 2' HYDROXYCHALCONE; 4 HYDROXYCHALCONE; BAICALEIN; BIOCHANIN A; BUTEIN; CHALCONE DERIVATIVE; CYTOCHROME P450 1A1; CYTOCHROME P450 INHIBITOR; DAIDZEIN; EPIGALLOCATECHIN GALLATE; EQUOL; ETHOXYRESORUFIN DEETHYLASE; GENISTEIN; ISOLIQUIRITIGENIN; KAEMPFEROL; LUTEOLIN; NARINGENIN; POLYPHENOL; QUERCETIN; RECOMBINANT PROTEIN; RESVERATROL; THEAFLAVIN; THEAFLAVIN 1; THEAFLAVIN 3,3' DIGALLATE; THEAFLAVINE 3' GALLATE; UNCLASSIFIED DRUG;

CONTROLLED STUDY; DRUG SCREENING; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REVIEW;

CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; FLAVONOIDS; HUMANS; MICROSOMES; RECOMBINANT PROTEINS; STILBENES; TOXICITY TESTS; TRANSFECTION;

EID: 34547809372     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.04.005     Document Type: Review

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