Pharmacokinetic and pharmacodynamic studies following percutaneous absorption of erythropoietin micropiles to rats

Journal of Controlled Release

Volumn 121, Issue 3, 2007, Pages 176-180

  Ito, Y ^a   Shiroyama, K ^a   Yoshimitsu, J ^a   Ohashi, Y ^a   Sugioka, N ^a   Takada, K ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Erythropoietin; Micropiles; Percutaneous route; Rats; Reticulocytes

Indexed keywords

ABSORPTION; DRUG DELIVERY; DRUG DOSAGE; HISTOLOGY; RATS;

ERYTHROPOIETIN; MICROPILES; PERCUTANEOUS ROUTE; RETICULOCYTES;

PHARMACOKINETICS;

POLYMER; RECOMBINANT ERYTHROPOIETIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; INJECTION; MALE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT; RETICULOCYTE COUNT; SELF DISSOLVING MICROPILES; STATISTICAL ANALYSIS;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; ERYTHROPOIETIN; INJECTIONS, SUBCUTANEOUS; MALE; RATS; RATS, WISTAR; RETICULOCYTES; SKIN ABSORPTION;

EID: 34547681734     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.05.028     Document Type: Article

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