Quantitative determination of apigenin and its metabolism in rat plasma after intravenous bolus administration by HPLC coupled with tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 855, Issue 2 SPEC. ISS., 2007, Pages 286-289

  Wan, Lili ^a   Guo, Cheng ^a   Yu, Qi ^a   Li, Yan ^a   Wang, Xiangwei ^b   Wang, Xiaolin ^b   Chen, Chunlin ^b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Medicilon Inc   (United States)

Author keywords

Apigenin; LC MS MS; Luteolin; Metabolism; Pharmacokinetics

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PHARMACOKINETICS; RATS;

APIGENIN; LUTEOLIN; TANDEM MASS SPECTROMETRY;

KETONES;

ACETONITRILE; APIGENIN; LUTEOLIN; METHANOL; MEVINOLIN; WATER;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; DEVICE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG METABOLISM; DRUG STRUCTURE; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUANTITATIVE ASSAY; RAT; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 34547678022     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.05.007     Document Type: Article

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