Soluble human leukocyte antigen-G5 in septic shock: Marked and persisting elevation as a predictor of survival

Critical Care Medicine

Volumn 35, Issue 8, 2007, Pages 1942-1947

  Monneret, Guillaume ^a   Voirin, Nicolas ^b   Krawice Radanne, Irène ^c   Bohé, Julien ^d   Lepape, Alain ^d   Rouas Freiss, Nathalie ^c   Carosella, Edgardo D ^c  

^a HÔPITAL NEUROLOGIQUE   (France)

^b UNIVERSITÉ LYON 1   (France)

^c Inst Univ d'Hématologie   (France)

^d CENTRE HOSPITALIER LYON SUD   (France)

Author keywords

Human leukocyte antigen DR; Human leukocyte antigen G; Immunosuppression; Monocyte; Septic shock

Indexed keywords

HLA G ANTIGEN; HLA G1 ANTIGEN; HLA G5 ANTIGEN; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIGEN DETECTION; ANTIGEN EXPRESSION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HUMAN; INTENSIVE CARE UNIT; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NEGATIVE FEEDBACK; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; SCORING SYSTEM; SEPTIC SHOCK; SOLUBILITY; SURVIVAL; SURVIVOR; UNIVERSITY HOSPITAL;

AGED; BIOLOGICAL MARKERS; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HLA-DR ANTIGENS; HUMANS; IMMUNOCOMPROMISED HOST; LOGISTIC MODELS; LYMPHOCYTES; MALE; MIDDLE AGED; MONOCYTES; ROC CURVE; SENSITIVITY AND SPECIFICITY; SHOCK, SEPTIC; SURVIVAL ANALYSIS;

EID: 34547652673     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000277039.84372.1C     Document Type: Article

References (34)

1. Hotchkiss RS, Karl IE: The pathophysiology and treatment of sepsis. N Engl J Med 2003; 348:138-150
2. Annane D, Bellissant E, Cavaillon JM: Septic shock. Lancet 2005; 365:63-78
3. Hotchkiss RS, Nicholson DW: Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol 2006; 6:813-822
4. Munford RS, Pugin J: Normal responses to injury prevent systemic inflammation and can be immunosuppressive. Am J Respir Crit Care Med 2001; 163:316-321
5. Reddy RC, Chen GH, Tekchandani PK, et al: Sepsis-induced immunosuppression: From bad to worse. Immunol Res 2001; 24:273-287
6. Monneret G: How to identify systemic sepsis-induced immunoparalysis. Adv Sepsis 2005; 4:42-49
7. Venet F, Pachot A, Debard AL, et al: Increased percentage of CD4+CD25+ regulatory T cells during septic shock is due to the decrease of CD4+CD25-lymphocytes. Crit Care Med 2004; 32:2329-2331
8. Carosella ED, Moreau P, Le Maoult J, et al: HLA-G molecules: From maternal-fetal tolerance to tissue acceptance. Adv Immunol 2003; 81:199-252
9. Bone RC, Balk RA, Cerra FB, et al: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992; 101:1644-1655
10. Monneret G, Lepape A, Voirin N, et al: Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock. Intensive Care Med 2006; 32:1175-1183
11. Le Gall JR, Lemeshow S, Saulnier F: A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 1993; 270:2957-2963
12. Rebmann V, Lemaoult J, Rouas-Freiss N, et al: Report of the Wet Workshop for Quantification of Soluble HLA-G in Essen, 2004. Hum Immunol 2005; 66:853-863
13. Paul P, Rouas-Freiss N, Moreau P, et al: HLA-G, -E, -F preworkshop: tools and protocols for analysis of non-classical class I genes transcription and protein expression. Hum Immunol 2000; 61:1177-1195
14. Menier C, Saez B, Horejsi V, et al: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: New tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol 2003; 64:315-332
15. Le Rond S, Azema C, Krawice-Radanne I, et al: Evidence to support the role of HLA-g5 in allograft acceptance through induction of immunosuppressive/ regulatory T cells. J Immunol 2006; 176:3266-3276
16. Rouas-Freiss N, Moreau P, Ferrone S, et al: HLA-G proteins in cancer: Do they provide tumor cells with an escape mechanism? Cancer Res 2005; 65:10139-10144
17. Rouas-Freiss N, Marchal RE, Kirszenbaum M, et al: The alpha1 domain of HLA-G1 and HLA-G2 inhibits cytotoxicity induced by natural killer cells: Is HLA-G the public ligand for natural killer cell inhibitory receptors? Proc Natl Acad Sci U S A 1997; 94:5249-5254
18. Riteau B, Rouas-Freiss N, Menier C, et al: HLA-G2, -G3, and -G4 isoforms expressed as nonmature cell surface glycoproteins inhibit NK and antigen-specific CTL cytolysis. J Immunol 2001; 166:5018-5026
19. Riteau B, Menier C, Khalil-Daher I, et al: HLA-G inhibits the allogeneic proliferative response. J Reprod Immunol 1999; 43:203-211
20. Lila N, Rouas-Freiss N, Dausset J, et al: Soluble HLA-G protein secreted by allo-specific CD4+ T cells suppresses the allo-proliferative response: A CD4+ T cell regulatory mechanism. Proc Natl Acad Sci U S A 2001; 98:12150-12155
21. Bahri R, Hirsch F, Josse A, et al: Soluble HLA-G inhibits cell cycle progression in human alloreactive T Lymphocytes. J Immunol 2006; 176:1331-1339
22. Liang S, Baibakov B, Horuzsko A: HLA-G inhibits the functions of murine dendritic cells via the PIR-B immune inhibitory receptor. Eur J Immunol 2002; 32:2418-2426
23. LeMaoult J, Krawice-Radanne I, Dausset J, et al: HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4+ T cells. Proc Natl Acad Sci U S A 2004; 101:7064-7069
24. Shiroishi M, Tsumoto K, Amano K, et al: Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc Natl Acad Sci U S A 2003; 100:8856-8861
25. Colonna M, Navarro F, Bellon T, et al: A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J Exp Med 1997; 186:1809-1818
26. Colonna M, Samaridis J, Cella M, et al: Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules. J Immunol 1998; 160:3096-3100
27. Fournel S, Aguerre-Girr M, Huc X, et al: Cutting edge: Soluble HLA-G1 triggers CD95/CD95 ligand-mediated apoptosis in activated CD8+ cells by interacting with CD8. J Immunol 2000; 164:6100-6104
28. Contini P, Ghio M, Poggi A, et al: Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation. Eur J Immunol 2003; 33:125-134
29. Moreau P, Adrian-Cabestre F, Menier C, et al: IL-10 selectively induces HLA-G expression in human trophoblasts and monocytes. Int Immunol 1999; 11:803-811
30. Ibrahim EC, Morange M, Dausset J, et al: Heat shock and arsenite induce expression of the nonclassical class I histocompatibility HLA-G gene in tumor cell lines. Cell Stress Chaperones 2000; 5:207-218
31. Moreau P, Faure O, Lefebvre S, et al: Glucocorticoid hormones upregulate levels of HLA-G transcripts in trophoblasts. Transplant Proc 2001; 33:2277-2280
32. Venet F, Pachot A, Debard AL, et al: Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism. J Immunol 2006; 177:6540-6547
33. Guisset O, Dilhuydy MS, Thiebaut R, et al: Decrease in circulating dendritic cells predicts fatal outcome in septic shock. Intensive Care Med 2006; 33:148-152
34. Ince MN, Harnisch B, Xu Z, et al: Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function. Immunology 2004; 112:531-542