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Volumn 7, Issue 4, 2007, Pages 275-281

No evidence for binding of clozapine, olanzapine and/or haloperidol to selected receptors involved in body weight regulation

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; BOMBESIN RECEPTOR; BOMBESIN RECEPTOR 3; BRADYKININ B2 RECEPTOR; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR 1; CHOLECYSTOKININ RECEPTOR; CLOZAPINE; DOPAMINE 1 RECEPTOR; ENDOTHELIN RECEPTOR; GALANIN RECEPTOR 1; HALOPERIDOL; HISTAMINE H1 RECEPTOR; HORMONE RECEPTOR; MELANIN CONCENTRATING HORMONE RECEPTOR; MELANOCORTIN 4 RECEPTOR; MUSCARINIC M1 RECEPTOR; NEUROKININ 1 RECEPTOR; NEUROPEPTIDE Y1 RECEPTOR; NEUROTENSIN RECEPTOR; NEUROTENSIN RECEPTOR 1; NEUROTRANSMITTER; OLANZAPINE; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN 6 RECEPTOR; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1;

EID: 34547646348     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500418     Document Type: Article
Times cited : (35)

References (64)
  • 1
    • 0033060332 scopus 로고    scopus 로고
    • Body weight gain induced by antipsychotic drugs: Mechanisms and management
    • Baptista T. Body weight gain induced by antipsychotic drugs: Mechanisms and management. Acta Psychiatr Scand 1999; 100: 3-16.
    • (1999) Acta Psychiatr Scand , vol.100 , pp. 3-16
    • Baptista, T.1
  • 9
    • 0036276522 scopus 로고    scopus 로고
    • Weight gain associated with increased food intake and low habitual activity levels in male adolescent schizophrenic inpatients treated with olanzapine
    • Gothelf D, Falk B, Singer P, Kairi M, Phillip M, Zigel L et al. Weight gain associated with increased food intake and low habitual activity levels in male adolescent schizophrenic inpatients treated with olanzapine. Am J Psychiatry 2002; 159: 1055-1057.
    • (2002) Am J Psychiatry , vol.159 , pp. 1055-1057
    • Gothelf, D.1    Falk, B.2    Singer, P.3    Kairi, M.4    Phillip, M.5    Zigel, L.6
  • 11
    • 0346731075 scopus 로고    scopus 로고
    • Clozapine's effects on body weight and resting metabolic rate: A case series
    • Procyshyn RM, Chau A, Tse G. Clozapine's effects on body weight and resting metabolic rate: A case series. Schizophr Res 2004; 66 159-162.
    • (2004) Schizophr Res , vol.66 , pp. 159-162
    • Procyshyn, R.M.1    Chau, A.2    Tse, G.3
  • 12
    • 0036221550 scopus 로고    scopus 로고
    • Atypical antipsychotics: Mechanism of action
    • Seeman P. Atypical antipsychotics: Mechanism of action. Can J Psychiatry 2002; 47: 27-38.
    • (2002) Can J Psychiatry , vol.47 , pp. 27-38
    • Seeman, P.1
  • 13
    • 0034785813 scopus 로고    scopus 로고
    • Genetic dissection of atypical antipsychotic-induced weight gain: Novel preliminary data on the pharmacogenetic puzzle
    • Basile VS, Masellis M, McIntyre RS, Meltzer HY, Lieberman JA, Kennedy JL. Genetic dissection of atypical antipsychotic-induced weight gain: novel preliminary data on the pharmacogenetic puzzle. J Clin Psychiatry 2001; 62(Suppl 23): 45-66.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 23 , pp. 45-66
    • Basile, V.S.1    Masellis, M.2    McIntyre, R.S.3    Meltzer, H.Y.4    Lieberman, J.A.5    Kennedy, J.L.6
  • 14
    • 0037202751 scopus 로고    scopus 로고
    • 759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain
    • Basile VS, Masellis M, De-Luca V, Meltzer HY, Kennedy JL. 759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain. Lancet 2002; 360: 1790-1791.
    • (2002) Lancet , vol.360 , pp. 1790-1791
    • Basile, V.S.1    Masellis, M.2    De-Luca, V.3    Meltzer, H.Y.4    Kennedy, J.L.5
  • 15
    • 4344622156 scopus 로고    scopus 로고
    • Pharmacogenetics of antipsychotic-induced weight gain
    • Correll CU, Malhotra AK. Pharmacogenetics of antipsychotic-induced weight gain. Psychopharmacology (Berl) 2004; 174: 477-489.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 477-489
    • Correll, C.U.1    Malhotra, A.K.2
  • 17
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet 2002; 359: 2086-2087.
    • (2002) Lancet , vol.359 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 18
    • 0038474172 scopus 로고    scopus 로고
    • Polymorphism of the promoter region of the serotonin 5-HT(2C) receptor gene and clozapine-induced weight gain
    • Reynolds GP, Zhang ZJ, Zhang XB. Polymorphism of the promoter region of the serotonin 5-HT(2C) receptor gene and clozapine-induced weight gain. Am J Psychiatry 2003; 160: 677-679.
    • (2003) Am J Psychiatry , vol.160 , pp. 677-679
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 19
    • 4644225416 scopus 로고    scopus 로고
    • Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals
    • Theisen FM, Hinney A, Bromel T, Heinzel-Gutenbrunner M, Martin M, Krieg JC et al. Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals. Psychiatr Genet 2004; 14: 139-142.
    • (2004) Psychiatr Genet , vol.14 , pp. 139-142
    • Theisen, F.M.1    Hinney, A.2    Bromel, T.3    Heinzel-Gutenbrunner, M.4    Martin, M.5    Krieg, J.C.6
  • 20
    • 0037202751 scopus 로고    scopus 로고
    • 759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain
    • Tsai SJ, Hong CJ, Yu W, Lin CH. 759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain. Lancet 2002; 360 1790.
    • (2002) Lancet , vol.360 , pp. 1790
    • Tsai, S.J.1    Hong, C.J.2    Yu, W.3    Lin, C.H.4
  • 22
    • 17644394540 scopus 로고    scopus 로고
    • Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis
    • Templeman LA, Reynolds GP, Arranz B, San L. Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. Pharmacogenet Genomics 2005; 15: 195-200.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 195-200
    • Templeman, L.A.1    Reynolds, G.P.2    Arranz, B.3    San, L.4
  • 24
    • 0032983548 scopus 로고    scopus 로고
    • Body weight and leptin plasma levels during treatment with antipsychotic drugs
    • Kraus T, Haack M, Schuld A, Hinze-Selch D, Kuhn M, Uhr M et al. Body weight and leptin plasma levels during treatment with antipsychotic drugs. Am J Psychiatry 1999; 156: 312-314.
    • (1999) Am J Psychiatry , vol.156 , pp. 312-314
    • Kraus, T.1    Haack, M.2    Schuld, A.3    Hinze-Selch, D.4    Kuhn, M.5    Uhr, M.6
  • 25
    • 0036809970 scopus 로고    scopus 로고
    • Are leptin and cytokines involved in body weight gain during treatment with antipsychotic drugs?
    • Baptista T, Beaulieu S. Are leptin and cytokines involved in body weight gain during treatment with antipsychotic drugs? Can J Psychiatry 2002; 47: 742-749.
    • (2002) Can J Psychiatry , vol.47 , pp. 742-749
    • Baptista, T.1    Beaulieu, S.2
  • 26
    • 33645214469 scopus 로고    scopus 로고
    • Early effects of olanzapine on serum levels of ghrelin, adiponectin and leptin in patients with schizophrenia
    • Hosojima H, Togo T, Odawara T, Hasegawa K, Miura S, Kato Y et al. Early effects of olanzapine on serum levels of ghrelin, adiponectin and leptin in patients with schizophrenia. J Psychophormacol 2006; 20: 75-79.
    • (2006) J Psychophormacol , vol.20 , pp. 75-79
    • Hosojima, H.1    Togo, T.2    Odawara, T.3    Hasegawa, K.4    Miura, S.5    Kato, Y.6
  • 27
    • 33746805519 scopus 로고    scopus 로고
    • Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents
    • Albaugh VL, Henry CR, Bello NT, Hajnal A, Lynch SL, Halle B et al. Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents. Obes Res 2006; 14: 36-51.
    • (2006) Obes Res , vol.14 , pp. 36-51
    • Albaugh, V.L.1    Henry, C.R.2    Bello, N.T.3    Hajnal, A.4    Lynch, S.L.5    Halle, B.6
  • 29
    • 0037837268 scopus 로고    scopus 로고
    • No evidence for a direct effect of clozapine on fat-cell formation and production of leptin and other fat-cell-derived factors
    • Hauner H, Rohrig K, Hebebrand J, Skurk T. No evidence for a direct effect of clozapine on fat-cell formation and production of leptin and other fat-cell-derived factors. Mol Psychiatry 2003; 8: 258-259.
    • (2003) Mol Psychiatry , vol.8 , pp. 258-259
    • Hauner, H.1    Rohrig, K.2    Hebebrand, J.3    Skurk, T.4
  • 30
    • 0029846298 scopus 로고    scopus 로고
    • Effects of clozapine on plasma cytokine and soluble cytokine receptor levels
    • Pollmacher T, Hinze-Selch D, Mullington J. Effects of clozapine on plasma cytokine and soluble cytokine receptor levels. J Clin Psychopharmacol 1996; 16: 403-409.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 403-409
    • Pollmacher, T.1    Hinze-Selch, D.2    Mullington, J.3
  • 31
    • 0035027629 scopus 로고    scopus 로고
    • KO's and organisation of peptidergic feeding behavior mechanisms
    • Beck B. KO's and organisation of peptidergic feeding behavior mechanisms. Neurosci Biobehav Rev 2001; 25: 143-158.
    • (2001) Neurosci Biobehav Rev , vol.25 , pp. 143-158
    • Beck, B.1
  • 32
    • 33645531332 scopus 로고    scopus 로고
    • Central effects of calcitonin receptor-stimulating peptide-1 on energy homeostasis in rats
    • Sawada H, Yamaguchi H, Shimbara T, Toshinai K, Mondal MS, Date Y et al. Central effects of calcitonin receptor-stimulating peptide-1 on energy homeostasis in rats. Endocrinology 2006; 147: 2043-2050.
    • (2006) Endocrinology , vol.147 , pp. 2043-2050
    • Sawada, H.1    Yamaguchi, H.2    Shimbara, T.3    Toshinai, K.4    Mondal, M.S.5    Date, Y.6
  • 33
    • 15444363610 scopus 로고    scopus 로고
    • Cannabinoids and the regulation of ingestive behaviour
    • Vickers SP, Kennett GA. Cannabinoids and the regulation of ingestive behaviour. Curr Drug Targets 2005; 6: 215-223.
    • (2005) Curr Drug Targets , vol.6 , pp. 215-223
    • Vickers, S.P.1    Kennett, G.A.2
  • 34
    • 2442568778 scopus 로고    scopus 로고
    • Bradykinin B2 receptor gene C-58T polymorphism and insulin resistance. A study on obese patients
    • Fallo F, Mulatero P, Vettor R, Scarda A, Della Mea P, Morello F et al. Bradykinin B2 receptor gene C-58T polymorphism and insulin resistance. A study on obese patients. Horm Metab Res 2004; 36 243-246.
    • (2004) Horm Metab Res , vol.36 , pp. 243-246
    • Fallo, F.1    Mulatero, P.2    Vettor, R.3    Scarda, A.4    Della Mea, P.5    Morello, F.6
  • 35
    • 2942692046 scopus 로고    scopus 로고
    • The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion
    • Ewert S, Johansson B, Holm M, Helander HF, Fandriks L. The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion. BMC Physiol 2003; 3: 1.
    • (2003) BMC Physiol , vol.3 , pp. 1
    • Ewert, S.1    Johansson, B.2    Holm, M.3    Helander, H.F.4    Fandriks, L.5
  • 36
    • 11144330035 scopus 로고    scopus 로고
    • Effect of bosentan (ETA/ETB receptor antagonist) on metabolic changes during stress and diabetes
    • Said SA, Ammar el SM, Suddek GM. Effect of bosentan (ETA/ETB receptor antagonist) on metabolic changes during stress and diabetes. Pharmacol Res 2005; 51: 107-115.
    • (2005) Pharmacol Res , vol.51 , pp. 107-115
    • Said, S.A.1    Ammar el, S.M.2    Suddek, G.M.3
  • 38
    • 0031936197 scopus 로고    scopus 로고
    • Secretin and vasoactive intestinal peptide receptors: Members of a unique family of G protein-coupled receptors
    • Ulrich II CD, Holtmann M, Miller LJ. Secretin and vasoactive intestinal peptide receptors: Members of a unique family of G protein-coupled receptors. Gastroenterology 1998; 114. 382-397.
    • (1998) Gastroenterology , vol.114 , pp. 382-397
    • Ulrich II, C.D.1    Holtmann, M.2    Miller, L.J.3
  • 39
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (150) of an enzymatic reaction
    • Cheng Y, Prusoff WH. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (150) of an enzymatic reaction. Biochem Pharmacol 1973; 22: 3099-3108.
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 40
    • 34547619332 scopus 로고    scopus 로고
    • http://www.gpcr.org/7tm/htmls/consortium.html.
  • 41
    • 0028077439 scopus 로고
    • Intermediate affinity and potency of clozapine and low affinity of other neuroleptics and of antidepressants at H3 receptors
    • Kathmann M, Schlicker E, Gothert M. Intermediate affinity and potency of clozapine and low affinity of other neuroleptics and of antidepressants at H3 receptors. Psychopharmacology (Berl) 1994; 116: 464-468.
    • (1994) Psychopharmacology (Berl) , vol.116 , pp. 464-468
    • Kathmann, M.1    Schlicker, E.2    Gothert, M.3
  • 45
    • 13344275875 scopus 로고    scopus 로고
    • Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor
    • Kohen R, Metcalf MA, Khan N, Druck T, Huebner K, Lachowicz JE et al. Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. J Neurochem 1996; 66: 47-56.
    • (1996) J Neurochem , vol.66 , pp. 47-56
    • Kohen, R.1    Metcalf, M.A.2    Khan, N.3    Druck, T.4    Huebner, K.5    Lachowicz, J.E.6
  • 46
    • 8244235137 scopus 로고    scopus 로고
    • Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity
    • Schoemaker H, Claustre Y, Fage D, Rouquier L, Chergui K, Curet O et al. Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther 1997; 280: 83-97.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 83-97
    • Schoemaker, H.1    Claustre, Y.2    Fage, D.3    Rouquier, L.4    Chergui, K.5    Curet, O.6
  • 47
    • 0032007608 scopus 로고    scopus 로고
    • Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
    • Arnt J, Skarsfeldt T. Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence. Neuropsychopharmacology 1998; 18: 63-101.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 63-101
    • Arnt, J.1    Skarsfeldt, T.2
  • 49
    • 34547625672 scopus 로고    scopus 로고
    • Milian MJ, Schreiber R, Dekeyne A, Rivet JM, Bervoets K, Mavridis M et al. S 16924
    • Milian MJ, Schreiber R, Dekeyne A, Rivet JM, Bervoets K, Mavridis M et al. S 16924
  • 51
    • 0033625757 scopus 로고    scopus 로고
    • 5-ht6 receptors as emerging targets for drug discovery
    • Branchek TA, Blackburn TP. 5-ht6 receptors as emerging targets for drug discovery. Annu Rev Pharmacol Toxicol 2000; 40: 319-334.
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 319-334
    • Branchek, T.A.1    Blackburn, T.P.2
  • 53
    • 0034711425 scopus 로고    scopus 로고
    • Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds
    • Richelson E, Souder T. Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci 2000; 68: 29-39.
    • (2000) Life Sci , vol.68 , pp. 29-39
    • Richelson, E.1    Souder, T.2
  • 54
    • 0037122780 scopus 로고    scopus 로고
    • Pyrrolo [1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies
    • Campiani G, Butini S, Gemma S, Nacci V, Fattorusso C, Catalanotti B. Pyrrolo [1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies. J Med Chem 2002; 45: 344-359.
    • (2002) J Med Chem , vol.45 , pp. 344-359
    • Campiani, G.1    Butini, S.2    Gemma, S.3    Nacci, V.4    Fattorusso, C.5    Catalanotti, B.6
  • 55
    • 34547617436 scopus 로고    scopus 로고
    • http://www.gpcr-org/7tm/ligand/Seeman/index.html.
  • 56
    • 34547620611 scopus 로고    scopus 로고
    • http://www.gpcr.org/7tm/ligand/Organon/index.html.
  • 57
    • 34547616737 scopus 로고    scopus 로고
    • http://www.emea.eu.int/humandocs/PDFs/EPAR/Zyprexa/H-115-Pl-en.pdf.
  • 58
    • 22944438384 scopus 로고    scopus 로고
    • Silvestre JS, Prous J. Research on adverse drug events. J. Muscarinic M3 receptor binding affinity could predict the risk of antipsychotics to induce type 2 diabetes. Methods Find Exp Clin Pharmacol 2005; 27: 289-304.
    • Silvestre JS, Prous J. Research on adverse drug events. J. Muscarinic M3 receptor binding affinity could predict the risk of antipsychotics to induce type 2 diabetes. Methods Find Exp Clin Pharmacol 2005; 27: 289-304.
  • 60
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
    • Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 1999; 20: 68-100.
    • (1999) Endocr Rev , vol.20 , pp. 68-100
    • Kalra, S.P.1    Dube, M.G.2    Pu, S.3    Xu, B.4    Horvath, T.L.5    Kalra, P.S.6
  • 61
    • 0031696573 scopus 로고    scopus 로고
    • Neuropharmacology of obesity: My receptors made me eat it
    • Stahl SM. Neuropharmacology of obesity: My receptors made me eat it. J Clin Psychiatry 1998; 59: 447-448.
    • (1998) J Clin Psychiatry , vol.59 , pp. 447-448
    • Stahl, S.M.1
  • 62
    • 0031724295 scopus 로고    scopus 로고
    • How to appease the appetite of psychotropic drugs
    • Stahl SM. How to appease the appetite of psychotropic drugs. J Clin Psychiatry 1998; 59: 500-501.
    • (1998) J Clin Psychiatry , vol.59 , pp. 500-501
    • Stahl, S.M.1
  • 63
    • 0035052252 scopus 로고    scopus 로고
    • Genetic variants of the serotonin system and weight change during clozapine treatment
    • Hong CJ, Lin CH, Yu YW, Yang KH, Tsai SJ. Genetic variants of the serotonin system and weight change during clozapine treatment. Pharmocagenetics 2001; 11: 265-268.
    • (2001) Pharmocagenetics , vol.11 , pp. 265-268
    • Hong, C.J.1    Lin, C.H.2    Yu, Y.W.3    Yang, K.H.4    Tsai, S.J.5
  • 64
    • 14844322355 scopus 로고    scopus 로고
    • Low gene expression conferred by association of an allele of the 5-HT2C receptor gene with antipsychotic-induced weight gain
    • Buckland PR, Hoogendoom B, Guy CA, Smith SK, Coleman SL, O'Donovan MC. Low gene expression conferred by association of an allele of the 5-HT2C receptor gene with antipsychotic-induced weight gain. Am J Psychiatry 2005; 162: 613-615.
    • (2005) Am J Psychiatry , vol.162 , pp. 613-615
    • Buckland, P.R.1    Hoogendoom, B.2    Guy, C.A.3    Smith, S.K.4    Coleman, S.L.5    O'Donovan, M.C.6


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