Regulated degradation of the HIV-1 Vpu protein through a βTrCP-independent pathway limits the release of viral particles

PLoS Pathogens

Volumn 3, Issue 7, 2007, Pages 0995-1004

  Estrabaud, Emilie ^a,b   Le Rouzic, Erwann ^a,b   Lopez Vergès, Sandra ^a,b   Morel, Marina ^a,b   Belaïdouni, Nadia ^a,b   Benarous, Richard ^a,b   Transy, Catherine ^a,b   Berlioz Torrent, Clarisse ^a,b   Margottin Goguet, Florence ^a,b  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

VPU PROTEIN; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; CDC25A PHOSPHATASE; CELL CYCLE PROTEIN; F BOX PROTEIN; FBXO5 PROTEIN, HUMAN; PROTEIN TYROSINE PHOSPHATASE; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE PROGRESSION; CONTROLLED STUDY; ENZYME SUBSTRATE; GENETIC CONSERVATION; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; VIRION; VIRUS ISOLATION; VIRUS PARTICLE; ANIMAL; CELL LINE; CERCOPITHECUS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; PATHOGENICITY; PHOSPHORYLATION; PHYSIOLOGY; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANIMALS; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; F-BOX PROTEINS; GENE EXPRESSION REGULATION, VIRAL; GENE PRODUCTS, VPU; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; UBIQUITIN; VIRUS REPLICATION;

EID: 34547628246     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0030104     Document Type: Article

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