The Human Immunodeficiency Virus Type 1 Vpu Protein Inhibits NF-κB Activation by Interfering with βTrCP-mediated Degradation of IκB

Journal of Biological Chemistry

Volumn 276, Issue 19, 2001, Pages 15920-15928

  Bour, Stephan ^b   Perrin, Christèle ^b   Akari, Hirofumi ^b   Strebel, Klaus ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CELLS; MUTAGENESIS; PROTEINS;

CYTOKINES;

VIRUSES;

CD4 ANTIGEN; CYTOKINE; I KAPPA B; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEASOME; PROTEIN BETA TRCP; PROTEIN TRCP; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; VPU PROTEIN; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; BTRC PROTEIN, HUMAN; CARRIER PROTEIN; CYSTEINE PROTEINASE; DNA BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; MULTIENZYME COMPLEX; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; TETRACYCLINE;

ARTICLE; ENZYME ACTIVATION; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; BIOLOGICAL MODEL; CD4+ T LYMPHOCYTE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; KINETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROMOTER REGION; REGULATOR GENE; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

ANTIGENS, CD4; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CARRIER PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; GENE PRODUCTS, VPU; GENES, VPU; GTP-BINDING PROTEINS; HELA CELLS; HIV-1; HUMANS; I-KAPPA B PROTEINS; KINETICS; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINANT FUSION PROTEINS; TETRACYCLINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035844173     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010533200     Document Type: Article

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