Pulmonary stem cells and the induction of tissue regeneration in the treatment of emphysema

International Journal of COPD

Volumn 2, Issue 2, 2007, Pages 131-139

  Lenssen, Josephine ^a   Stolk, Jan ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Alveolar growth; Emphysema; Repair

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

BONE PAIN; BRONCHIOLE; BRUSH BORDER; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL LABELING; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CELL SHAPE; CELLULAR DISTRIBUTION; CHAPPED LIPS; CLARA CELL; CLINICAL TRIAL; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRY SKIN; EAR DISEASE; EMPHYSEMA; ENDOTHELIUM CELL; EPITHELIZATION; HEMATOPOIETIC STEM CELL; HUMAN; HYPERLIPIDEMIA; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; MESENCHYMAL STEM CELL; MYALGIA; NEUROSECRETORY CELL; NONHUMAN; PATHOGENESIS; PRURITUS; REVIEW; RISK FACTOR; SIDE EFFECT; STEM CELL; STEM CELL TRANSPLANTATION; TRACHEA MUCOSA;

ANIMALS; EMPHYSEMA; HUMANS; LUNG; RECEPTORS, RETINOIC ACID; REGENERATION; RESPIRATORY SYSTEM AGENTS; STEM CELLS; TREATMENT OUTCOME; TRETINOIN;

EID: 34547625455     PISSN: 11769106     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (42)

1. Aliotta JM, Keane P, Passero M, et al. 2006. Bone marrow production of lung cells: The impact of G-CSF, cardiotoxin, graded doses of irradiation, and subpopulation phenotype. Exp Hematol, 34:230-41.
2. Aoshiba K, Yokohori N, Nagai A. 2003. Alveolar wall apoptosis causes lung destruction and emphysematous changes. Am J Respir Cell Mol Biol, 28:555-62.
3. Avril-Delplanque A, Casal I, Castillon N, et al. 2005. Aquaporin-3 Expression in Human Fetal Airway Epithelial Progenitor Cells. Stem Cells, 23:992-1001.
4. 2 does not enhance development of airway epithelium from bone marrow. Mol Ther, 12:680-6.
5. Belloni PN, Garvin L, Mao CP, et al. 2000. Effects of all-trans-retinoic acid in promoting alveolar repair. Chest, 117(Suppl 1):235S-41S.
6. Bender Kim CF, Jackson EL, Woolfenden AE, et al. 2005. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell, 121:823-35.
7. Berne RM, Levy MN, Koeppen BM, et al. 2004. Physiology. 5th ed. p. 453.
8. Borthwick DW, Shahbazian M, Krantz QT, et al. 2001. Evidence for stem-cell niches in the tracheal epithelium. Am J Respir Cell Mol Biol, 24:662-70.
9. Brooks AD, Tong W, Benedetti F, et al. 2000. Inhaled aerosolization of all-trans-retinoic acid for targeted pulmonary delivery. Cancer Chemother Pharmacol, 46:313-18.
10. Buckpitt A, Chang AM, Weir A, et al. 1995. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. IV. Metabolism of naphthalene and naphthalene oxide in microdissected airways from mice, rats, and hamsters. Mol Pharmacol, 47:74-81.
11. Cardoso WV, Williams MC, Mitsialis SA, et al. 1995. Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro. Am J Respir Cell Mol Biol, 12:464-76.
12. Chambon. 1996. A decade of molecular biology of retinoic acid receptors. FASEB J, 10:940-54.
13. Churg A, Wang RD, Tai H, et al. 2004. Tumor necrosis factor-α drives 70% of cigarette smoke-induced emphysema in the mouse. Am J Respir Crit Care Med, 170:492-8.
14. Coller HA, Khrapko K, Herrero-Jimenez P, et al. 2005. Clustering of mutant mitochondrial DNA copies suggests stem cells are common in human bronchial epithelium. Mutat Res, 578:256-71.
15. Dahlin K, Mager EM, Allen L, et al. 2004. Identification of genes differentially expressed in rat alveolar type I cells. Am J Respir Cell Mol Biol, 31: 309-16.
16. Ding Q, Jia XS, Zhou Y. 2004. Study of tracheal regeneration after injury induced by 5-fluorouracil in rats. Zhonghua Bing Li Xue Za Zhi, 33:143-5.
17. Dupuit F, Gaillard D, Hinnrasky J, et al. 2000. Differentiated and functional human airway epithelium regeneration in tracheal xenografts. Am J Physiol Lung Cell Mol Physiol, 278:L165-76.
18. Foliguet B, Grignon G. 1980. Type III pneumocyte. The alveolar brush-border cell in rat lung. Study by transmission electron microscopy (author's transl). Poumon Coeur, 36:149-53.
19. Fujita M, Ye Q, Ouchi H, et al. 2004. Retinoic acid fails to reverse emphysema in adult mouse models. Thorax, 59:224-30.
20. Gibbs DF, Warner RL, Weiss SJ, et al. 1999. Characterization of matrix metalloproteinases produced by rat alveolar macrophages. Am J Respir Cell Mol Biol, 20:1136-44.
21. Gomperts BN, Belperio JA, Rao PN, et al. 2006. Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury. J Immunol, 176:1916-27.
22. Hind M, Maden M. 2004. Retinoic acid induces alveolar regeneration in the adult mouse lung. Eur Respir J, 23:20-7.
23. Hong KU, Reynolds SD, Watkins S, et al. 2004a. In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am J Physiol Lung Cell Mol Physiol, 286:L643-9.
24. Hong KU, Reynolds SD, Watkins S, et al. 2004b. Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol, 164:577-88.
25. da Hora K, Valenca SS, Porto LC. 2005. Immunohistochemical study of tumor necrosis factor-alpha, matrix metalloproteinase-12, and tissue inhibitor of metalloproteinase-2 on alveolar macrophages of BALB/c mice exposed to short-term cigarette smoke. Exp Lung Res, 31:759-70.
26. Ishizawa K, Kubo H, Yamada M, et al. 2004. Bone marrow-derived cells contribute to lung regeneration after elastase-induced pulmonary emphysema. FEBS Lett, 556:249-52.
27. Kumar P, Clark M. 2002. Clinical Medicine; Respiratory Disease. p. 863.
28. Liang SX, Summer R, Sun X, Fine A. 2005. Gene expression profiling and localization of Hoechst-effluxing CD45- and CD45+ cells in the embryonic mouse lung. Physiol Genomics, 23:172-81.
29. Liu JY, Nettesheim P, Randell SH. 1994, Growth and differentiation of tracheal epithelial progenitor cells. Am J Physiol, 266:L296-307.
30. Massaro GD, Massaro D. 1997. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat Med, 3:675-7.
31. Massaro GD, Massaro D, Chambon P. 2003. Retinoic acid receptor-alpha regulates pulmonary alveolus formation in mice after, but not during, perinatal period. Am J Physiol Lung Cell Mol Physiol, 284:L431-3.
32. Majka SM, Beutz MA, Hagen M, et al. 2005. Identification of novel resident pulmonary stem cells: form and function of the lung side population. Stem Cells, 23:1073-81.
33. Mao JT, Goldin JG, Dermand J, et al. 2002. A pilot study of All-trans-Retinoic Acid for the treatment of human emphysema, Am J Respir Crit Care Med, 165:718-23.
34. McGowan S, Jackson SK, Jenkins-Moore M, et al. 2000. Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers. Am J Respir Cell Mol Biol, 23:162-7.
35. 2. Expir Mol Pathol, 22:142-150.
36. Nabeyrat E, Corroyer S, Epaud R, et al. 2000. Retinoic acid-induced proliferation of lung alveolar epithelial cells is linked to p21CIP1 downregulation. Am J Physiol Lung Cell Mol Physiol, 278:LA2-L50.
37. Nakajoh M, Fukushima T, Suzuki T, et al. 2003. Retinoic acid inhibits elastase-induced injury in human lung epithelial cell lines. Am J Respir Cell Mol Biol, 28:296-304.
38. Snyder JM, Jenkins-Moore M, Jackson SK, et al. 2005. Alveolarization in retinoic acid receptor-beta-deficient mice. Pediatr Res, 57:384-91.
39. Summer R, Kotton DN, Sun X, et al. 2003. Side population cells and Bcrpl expression in lung. Am J Physiol Lung Cell Mol Physiol, 285: L97-104.
40. Tepper J, Pfeiffer J, Aldrich M. 2000. Can retinoic acid ameliorate the physiologic and morphologic effects of elastase instillation in the rat? Chest, 117:242S-4S.
41. Theise ND, Henegariu O, Grove J, et al. 2002. Radiation pneumonitis in mice: a severe injury model for pneumocyte engraftment from bone marrow. Exp Hematol, 30:1333-8.
42. Witherden IR, vanden Bon EJ, Goldstraw P, et al. 2004. Primary human alveolar type II epithelial cell chemokine release: effects of cigarette smoke and neutrophil elastase. Am J Respir Cell Mol Biol, 30:500-9.