Inhaled aerosolization of all-trans-retinoic acid for targeted pulmonary delivery

Cancer Chemotherapy and Pharmacology

Volumn 46, Issue 4, 2000, Pages 313-318

  Brooks, Ari D ^a   Tong, William ^a   Benedetti, Fabio ^a   Kaneda, Yoshikazu ^a   Miller, Vincent ^a   Warrell Jr , Raymond P ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

All trans retinoic acid; Chemoprevention; Inhalers

Indexed keywords

RETINOIC ACID;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG FORMULATION; HUMAN; HYPERCALCEMIA; HYPERLIPIDEMIA; LIVER DYSFUNCTION; LUNG DISEASE; LUNG EMPHYSEMA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETON MALFORMATION;

EID: 0033774621     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800000148     Document Type: Article

References (24)

1. Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin
2. Comparison of low-dose isotretinoin with beta carotene to prevent oral carcinogenesis
3. Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: A randomized trial
4. Acute promyelocytic leukemia
5. All-trans retinoic acid significantly increases 5-year survival in acute promyelocytic leukemia: An updated analysis of the New York study
6. Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck
7. Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia
8. Adjuvant treatment of stage I lung cancer with high-dose vitamin A
9. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats
10. Clinical and laboratory adverse effects associated with long-term, low-dose isotretinoin: Incidence and risk factors
11. Phase I evaluation of all-trans-retinoic acid in adults with solid tumors
12. Phase II study of all-trans-retinoic acid and α-interferon in patients with advanced non-small cell lung cancer
13. 13-cis-retinoic acid and interferon α-2a: Effective combination therapy for advanced squamous cell carcinoma of the skin
14. Initial clinical trial of the retinoid receptor pan agonist 9-cis-retinoic acid
15. Phase I trial of 9-cis-retinoic acid in adults with solid tumors
16. Retinoids in cancer chemoprevention
17. Guidelines for the diagnosis and management of asthma. IV. Overview of approaches to asthma therapy
18. A simplified method for endotracheal intubation in the rat
19. Identification and quantitation of alltrans and 13-cis-retinoic acid and 13-cis-4-oxoretinoic acid in human plasma
20. Retinoid chemoprevention of aerodigestive cancer: From basic research to the clinic
21. Second malignant tumors in head and neck squamous cell carcinoma: The overshadowing threat for patients with early-stage disease
22. Incidence of local recurrence and second primary tumors in resected stage I lung cancer
23. Retinoid-dependent induction of the in vivo and in vitro metabolism of retinoic acid in tissues of the vitamin A-deficient hamster
24. Continuous treatment with all-trans-retinoic acid causes a progressive reduction in plasma drug concentrations: Implications for relapse and retinoid 'resistance' in patients with acute promyelocytic leukemia